Irradiation on Extramedullary Plasmacytoma of Vulva : A case report

Tirawan Sutedja (Departemen Radioterapi RSUPN dr. Cipto Mangunkusumo, Fakultas Kedokteran Universitas Indonesia)
Nana Supriana
Angela Giselvania
Henry Kodrat

Radioterapi & Onkologi Indonesia
Vol 13, No 1 (2022): Volume 13 No.1 January 2022

Plasma cell neoplasm is a clonal plasma cell malignancy which is the result of B cell differentiation with special characteristics the presence of immunoglobulin secretion. The clinical presentation varies from monoclonal gammopathy to plasma cell leukemia. Only five to six percent of plasma cell neoplasms manifest as plasmacytoma.Solitary extramedullary plasmacytoma (EMP) in the vulva region is a rare case. The current study presents a recurrence case of EMP in left labia minora-vulva in 61-years-old patients who have undergone surgery with a complete response. Radiotherapy was given with a total dose of External Beam Radiotherapy (EBRT) 50.4 Gy and continued with brachytherapy cylinder intravagina five Gy in three fractions. Six months after complete radiation, there was no recurrence, metastasis or progression at follow-up.