ad-Dawaa : Journal of Pharmaceutical Sciences
Vol 5 No 2 (2022)

Antioxidant Activity Study of Zingiber Zerumbet Rhizome Extract and Fraction

Haeria Doloking (Universitas Islam Negeri Alauddin Makassar)
Mukhriani (UIN Alauddin Makassar)
Rima Amalia (UIN Alauddin Makassar)
Andri Anugrah Pratama (UIN Alauddin Makassar)



Article Info

Publish Date
30 Dec 2022

Abstract

Zingiber zerumbet is a member of the Zingiberaceae family with known pharmacological potentials. This study aims to characterize the phytochemical elements and evaluate the antioxidant potential of the methanol extract, soluble ethyl acetate, and n-hexane-soluble fractions of Zingiber zerumbet rhizome. Identify secondary metabolites for the alkaloids, saponins, flavonoids, polyphenols, tannins, and steroids/triterpenoids using the chemical reaction method in test tubes. Antioxidant activity was determined based on DPPH absorbance measurements using UV-Vis Spectrophotometry. The methanolic extract contained alkaloids, flavonoids, polyphenols/tannins, steroids, and triterpenoids. The ethyl acetate soluble fraction contained flavonoids and polyphenols/tannins, and the n-hexane soluble fraction contained alkaloids and flavonoids. The free radical scavenging activities of ascorbic acid, methanol extract, ethyl acetate, and the n-hexane soluble fraction were 7.79; 100,956; 69,476, and 77,780 ppm, respectively. The findings indicated that the methanolic extract, ethyl acetate, and n-hexane soluble fraction were suitable sources of natural antioxidants.

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Journal Info

Abbrev

addawaa

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology

Description

ad-Dawaa Journal of Pharmaceutical Sciences (DJPS) merupakan jurnal yang terbit dua kali dalam setahun, yaitu setiap Juni dan Desember. Jurnal ini fokus pada seluruh bidang terkait ilmu farmasi, termasuk biologi farmasi, farmakokimia, farmakologi, farmasi klinik dan teknologi farmasi. Jurnal ini ...