Jurnal Indah Sains dan Klinis
Vol 2 No 3 (2021): Jurnal Indah Sains dan Klinis

Efek Antihiperlipidemia Kombucha Daun Kari (Murraya koenigii (L.) Spreng) pada Tikus Putih Jantan (Rattus norvegicus) yang Diinduksi Dengan High Fat dan PTU

Hardyanto Napitupulu, (Unknown)
Muharni Saputri (Unknown)
Salmah Handayani Lubis (Unknown)
Muflihah Fujiko (Unknown)
Ernawaty Ginting (Unknown)



Article Info

Publish Date
31 Dec 2021

Abstract

Curry leaves (Murraya koenigii (L.) Spreng) is a plant that is often used in cooking spices that are high in fat because curry leaves contain secondary metabolite compounds such asalkaloids, glycosides, and flavonoids that serve to inhibit the growth of free radicals and lower cholesterol levels. Generally curry leaves are processed traditionally in a simple form, while research will process curry leaves in the form of fermented beverages in the form of kombucha tea. This study aims to explore the process of making curry leaf kombucha tea and know the antihiperlipidemia effect. This research is descriptive and experimental, including material collection, simplisia making, phytochemical screening, fermentation of curry leaf kombucha, evaluation of dosage quality, testing of triglyceride levels in rats with Electrode-Based Biosensor technique. The mice used in this study were 25 and divided into 5 test groups. K1 (negative blank), K2 (Simvastatin), K3 (dose 100 ml), K4 (dose 150 ml), K5 (dose 200 ml) induced using 80% egg yolk and PTU 0.2%. The results showed that the quality evaluation of kombucha tea gave good results to pH 3.08-3.44 and did not experience changes in taste and smell. In the group of 5 doses of 200 ml with kombucha tea administration on the 7th to 15th day, it was shown that cholesterol levels decreased from 253.0 mg/dL to 92.2 ml/dL where these results were close to comparing (simvastatin) from 247.8 mg/dL to 79.2 mg/dL

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Journal Info

Abbrev

jisk

Publisher

Subject

Dentistry Health Professions Medicine & Pharmacology Nursing

Description

The Jurnal Indah Sains dan Klinis (JISK) is a journal about health which contains scientific and clinical issues published by the Yayasan Penelitian dan Inovasi Sumatera (YPIS) which includes studies on Pharmacy, Medicine, Nursing, Midwifery, Chemistry, Biology, Microbiology, Tissue Culture and ...