Jurnal Medika Veterinaria
Vol 17, No 1 (2023): J.Med.Vet

Efficacy of Jatropha (Jatropha curcas L.) Sap Cream on Total Differential Leucocytes in Inflammatory Phase of Wound Healing on Mice Skin (Mus musculus) : A Review

Aufira Fildza Bahittah (Program Studi Pendidikan Dokter Hewan Fakultas Kedokteran Hewan Universitas Syiah Kuala)
M. Nur Salim (Laboratorium Patologi Fakultas Kedokteran Hewan Universitas Syiah Kuala, Banda Aceh)
Triva Murtina Lubis (Laboratorium Fisiologi Fakultas Kedokteran Hewan Universitas Syiah Kuala, Banda Aceh)
T. Zahrial Helmi (Laboratorium Biokimia Fakultas Kedokteran Hewan Universitas Syiah Kuala, Banda Aceh)
Abdul Harris (Laboratorium Farmakologi Fakultas Kedokteran Hewan Universitas Syiah Kuala, Banda Aceh)
Wahyu Eka Sari (Laboratorium Riset Veteriner Fakultas Kedokteran Hewan Universitas Syiah Kuala, Banda Aceh)



Article Info

Publish Date
14 Jun 2023

Abstract

A wound is a damage to the integrity of the epithelium of the skin. There are three phases of wound healing process, the first phase is inflammatory phase, the second phase is fibroplasia phase, and the third is maturation phase. Inflammation that occurs during the wound healing process should be limited because it would cause the wound to undergo an abnormal healing process and pathological inflammation if it persists. The aim of this study was to determine the efficacy of jatropha (Jatropha curcas L.) sap cream on total differential leucocytes in inflammatory phase of wound healing on mice skin. The method used was literature study using qualitatSive methods. Data used in this study refers to the result of studies which have been conducted and published in national and international online journal. Result of data analysis showed that Jatropha sap cream was effectively limiting and  inhibiting the leucocytes accumulation in inflammatory area and stimulated new blood vessels formation (angiogenesis) in inflammatory phase of wound healing in mice skin. Based on the result of this study, it can be concluded that the Jatropha sap cream could reduce the number of differential leucocytes in inflammatory phase of wound healing on mice skin.

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Journal Info

Abbrev

JMV

Publisher

Subject

Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology Veterinary

Description

Jurnal Medika Veterinaria is published biannually in February and August. The scope of this journal includes Veterinary Medicine, Animal Science, Science, and Medicine. The journal accepts original research papers, case study, and review article. All submissions are evaluated by peer reviewers who ...