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All Journal Jurnal Medika Veterinaria
Aufira Fildza Bahittah
Program Studi Pendidikan Dokter Hewan Fakultas Kedokteran Hewan Universitas Syiah Kuala
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology Veterinary

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Efficacy of Jatropha (Jatropha curcas L.) Sap Cream on Total Differential Leucocytes in Inflammatory Phase of Wound Healing on Mice Skin (Mus musculus) : A Review Aufira Fildza Bahittah; M. Nur Salim; Triva Murtina Lubis; T. Zahrial Helmi; Abdul Harris; Wahyu Eka Sari
Jurnal Medika Veterinaria Vol 17, No 1 (2023): J.Med.Vet
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.med.vet..v17i1.23542

Abstract

A wound is a damage to the integrity of the epithelium of the skin. There are three phases of wound healing process, the first phase is inflammatory phase, the second phase is fibroplasia phase, and the third is maturation phase. Inflammation that occurs during the wound healing process should be limited because it would cause the wound to undergo an abnormal healing process and pathological inflammation if it persists. The aim of this study was to determine the efficacy of jatropha (Jatropha curcas L.) sap cream on total differential leucocytes in inflammatory phase of wound healing on mice skin. The method used was literature study using qualitatSive methods. Data used in this study refers to the result of studies which have been conducted and published in national and international online journal. Result of data analysis showed that Jatropha sap cream was effectively limiting and  inhibiting the leucocytes accumulation in inflammatory area and stimulated new blood vessels formation (angiogenesis) in inflammatory phase of wound healing in mice skin. Based on the result of this study, it can be concluded that the Jatropha sap cream could reduce the number of differential leucocytes in inflammatory phase of wound healing on mice skin.
Co-Authors Abdul Harris M Nur Salim T. Zahrial Helmi Triva Murtina Lubis