Jurnal Biosains Pascasarjana
Vol. 26 No. 1 (2024): JURNAL BIOSAINS PASCASARJANA

DIFFERENCES IN INTERFERON GAMMA LEVELS IN TREATMENT OF TUBERCULOSIS IN INTENSIVE PHASE AND ADVANCED PHASE

Kuncara, Rachmad Bayu (Unknown)
SY. Didik Widiyanto (Unknown)
Ririh Jatmi Wikandari (Unknown)
Wiwit Sulistyasmi (Unknown)



Article Info

Publish Date
01 Jul 2024

Abstract

Tuberculosis (TB) is a chronic infectious disease caused by Mycobacterium tuberculosis complex (MTBC). Anti-tuberculosis drugs given to active TB sufferers consist of 3 or 4 combinations. Tuberculosis treatment is divided into intensive phase treatment (2 weeks) and continuation phase (16 weeks / 4 months). Interferon gamma (IFN γ) is a protein belonging to the cytokine family which plays a role in eliminating MTB bacteria through a cell-mediated immunity mechanism. The aim of this study was to analyze differences in gamma interferon levels in the intensive phase and advanced phase of tuberculosis treatment. This research method is an analytical observational study with a cross-sectional design (cross sectional study). The research design used was a randomized post test only control group design. Data were analyzed using the Kruskal Wallis test with statistical test results obtained with a p value of 0.033 (> 0.05), meaning there was a difference in IFN γ levels in the intensive phase and advanced phase of tuberculosis treatment.

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Journal Info

Abbrev

BIOPASCA

Publisher

Subject

Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Immunology & microbiology

Description

Jurnal Biosains Pascasarjana is published not only for the publication of research results from graduates, as one of the graduation requirements but also for public that contains a discussion of the natural content, responses of living things, and their ...