Syifa' MEDIKA: Jurnal Kedokteran dan Kesehatan
Vol 15, No 1 (2024): Syifa' MEDIKA: Jurnal Kedokteran dan Kesehatan

Effectiveness of Anthocyanins on Kidney Fibrosis; A Systemic Literature Review

Lusiana, Evi (Unknown)
Azizah, Aida Nur (Unknown)
Islami, Arya Putera (Unknown)



Article Info

Publish Date
30 Sep 2024

Abstract

Renal fibrosis refers to the abnormal accumulation of extracellular matrix during the process of tissue repair. Kidney fibrosis is mostly caused by chronic inflammation, which leads to tissue remodeling and subsequently impairs kidney function, resulting in a reduction in the glomerular filtration rate (GFR). Reduced glomerular filtration rate (GFR) can elevate blood concentrations of urea and creatinine. The chemicals known as anthocyanins possess anti-inflammatory and antioxidant characteristics, hence potentially enhancing renal function. This study was conducted based on a literature review approach, utilizing journal papers published over the past decade (2015-2024) obtained from Pubmed, Science Direct, and Google Scholar. This article aims to represent the diverse scientific investigations made on the efficacy of anthocyanins in enhancing renal function in cases with renal fibrosis. The present study indicates that anthocyanins have a positive impact on kidney function by effectively lowering urea and creatinine levels in individuals with renal fibrosis.

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Journal Info

Abbrev

syifamedika

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology Public Health

Description

Syifa MEDIKA published by Faculty of Medicine, University of Muhammadiyah Palembang is a peer-reviewed journal that published two times a year: September and March. Syifa MEDIKA is a national peer-reviewed and open access journal. We accept original article, case report, and literature review from ...