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All Journal Syifa' MEDIKA: Jurnal Kedokteran dan Kesehatan
Islami, Arya Putera
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Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology Public Health

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Effectiveness of Anthocyanins on Kidney Fibrosis; A Systemic Literature Review Lusiana, Evi; Azizah, Aida Nur; Islami, Arya Putera
Syifa'Medika Vol 15, No 1 (2024): Syifa' MEDIKA: Jurnal Kedokteran dan Kesehatan
Publisher : Faculty of Medicine

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32502/sm.v15i1.7932

Abstract

Renal fibrosis refers to the abnormal accumulation of extracellular matrix during the process of tissue repair. Kidney fibrosis is mostly caused by chronic inflammation, which leads to tissue remodeling and subsequently impairs kidney function, resulting in a reduction in the glomerular filtration rate (GFR). Reduced glomerular filtration rate (GFR) can elevate blood concentrations of urea and creatinine. The chemicals known as anthocyanins possess anti-inflammatory and antioxidant characteristics, hence potentially enhancing renal function. This study was conducted based on a literature review approach, utilizing journal papers published over the past decade (2015-2024) obtained from Pubmed, Science Direct, and Google Scholar. This article aims to represent the diverse scientific investigations made on the efficacy of anthocyanins in enhancing renal function in cases with renal fibrosis. The present study indicates that anthocyanins have a positive impact on kidney function by effectively lowering urea and creatinine levels in individuals with renal fibrosis.
Co-Authors Azizah, Aida Nur Evi Lusiana