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All Journal SAINS MEDIKA : JURNAL KEDOKTERAN DAN KESEHATAN Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universitas Sriwijaya Biomedical Journal of Indonesia Syifa' MEDIKA: Jurnal Kedokteran dan Kesehatan Journal of Islamic Nursing Jurnal Kreativitas PKM SRIWIJAYA JOURNAL OF MEDICINE Jurnal Kesehatan Medica Hospitalia Indonesian Journal of Clinical Pathology and Medical Laboratory (IJCPML) Jurnal Pengabdian Masyarakat: Humanity and Medicine Indonesian Community Empowerment Journal International Archives of Medical Sciences and Public Health International Journal of Islamic and Complementary Medicine Journal of Child, Family, and Consumer Studies Mega Buana Journal of Innovation and Community Service (JICS) Jurnal Profesi Guru Indonesia
Evi Lusiana
Department Of Pharmacology, Faculty Of Medicine, Sriwijaya University, Palembang, Indonesia
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Computer Science & IT Dentistry Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Mathematics Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Other

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THE POTENTIAL OF BAY LEAVE (SYZYGIUM POLYANTHUM) AS AN ANTI-DIABETIC AGENT Wildan Dwi Putra Widodo; Nita Parisa; Nia Savitri Tamzil; Evi Lusiana; Nafrah Ardita; Amira Azra Arisa Putri; Sindy Bintang Permata; Aisyah Fristania Ditamor
International Journal of Islamic and Complementary Medicine Vol. 4 No. 2 (2023): International Journal of Islamic and Complementary Medicine
Publisher : International Islamic Medicine Forum

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55116/IJICM.V4I2.60

Abstract

Non-communicable disease prevalence continues to increase in Indonesia. One of the top 10 causes of death is non-communicable disease, and diabetes mellitus is on the list. Genetics, advanced age, obesity, stress, hypertension, smoking, and physical inactivity are risk factors that might result in diabetes mellitus. Despite advancements in mainstream anti-diabetic treatment, traditional medical practices continue to exist in several nations. Syzygium polyanthum is the herb that diabetic patients most frequently utilize in the traditional therapy of their illness, according to research on diabetic patients at the Health Community Center in Sering, Medan, Indonesia. The research team was interested in figuring out whether bay leaves showed any potential as an anti-diabetic agent based on the previous description. In this study, secondary literature from research publications is used in a literature review with a descriptive method. Several studies have suggested that bay leaves could potentially be used for the prevention and treatment of diabetes mellitus.
Risk Factors of Scabies In Students Of Aulia Cendikia Islamic Boarding School, Palembang Fifa Argentina; Debby Handayati Harahap; Evi Lusiana
Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universitas Sriwijaya Vol. 6 No. 3 (2019): Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universi
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/jkk.v6i3.121

Abstract

Scabies is a skin disease caused by infestation and sensitization of Sarcoptes scabiei var. hominis. Scabies can infect everyone at all ages, races, genders and social economic levels. This disease is usually found in places such as dormitories, orphanages, prisons, islamic boarding schools that lack personal hygiene. Observational analytic research with cross sectional design has been carried out at boarding school Aulia Cendikia in Palembang from June to December 2017. There were 199 samples of students of Aulia Cendikia boarding school in Palembang city that met the inclusion criteria. In this study, there were no age differences between students with or without scabies (p = 0.374; p> 0.05). This study showed that the number of people per room was the factor that most contributed to the incidence of scabies (PR = 2.746, p = 0.002) followed by personal hygiene (PR = 2.333, p = 0.007) and gender (PR = 2.068, p = 0.019). Number of people in the room, personal hygiene and gender are risk factors for scabies at the Aulia Cendikiaislamic boarding school in Palembang.
Optimalisasi Pengetahuan Tokoh Masyarakat Mengenai Penyakit Asam Urat Melalui Sosialisasi Kesehatan Evi Lusiana; Nia Savitri Tamzil; Nita Parisa; Desi Oktariana; Gita Dwi Prasasty; Indri Seta Septadina
Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universitas Sriwijaya Vol. 9 No. 1 (2022): Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universi
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/jkk.v9i1.209

Abstract

Penyakit asam urat merupakan dalah satu penyakit yang banyak diderita masyarakat yang ditandai dengan rasa nyeri pada persendian yang disebabkan endapan kristal monosodium urat pada sendi. Sosialisasi kesehatan merupakan upaya perubahan perilaku manusia yang dilakukan melalui pendekatan edukatif. Tujuan enelitian ini mengetahui pengaruh sosialisasi kesehatan mengenai penyakit asam urat terhadap peningkatan pengetahuan pada tokoh masyarakat. Desain penelitian adalah pra eksperimental one group pra test post test design. Sampel yang diambil sebanyak 70 responden yang berasal dari tokoh masyarakat di Kelurahan Kutobatu Palembang, Sumatera Selatan. Data penelitian ini di ambil dengan menggunakan kuesioner. Data dianalisis dengan mengunakan uji wilcoxon dengan tingkat kemaknaan 0,05. Hasil penelitian menunjukan tingkat pengetahuan sebelum intervensi berada pada kategori kurang dengan persentase 75% dan sesudah intervensi berada pada kategori baik dengan persentase 90%. Hasil uji statistic wilcoxon dimana p-value=0,02 < α=0,05. Dapat disimpulkan terdapat pengaruh sosialisasi kesehatan terhadap peningkatan pengetahuan tokoh masyarakat di Kelurahan Kutobatu Palembang, Sumatera Selatan.
EPIDEMIOLOGICAL AND ETIOPATHOGENESIS ASPECTS OF LEPROSY Desi Oktariana; Fifa Argentina; Kemas Ya’kub Rahadiyanto; Phey Liana; Evi Lusiana; Nia Savitri Tamzil; Gita Dwi Prasasty
Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universitas Sriwijaya Vol. 11 No. 1 (2024): Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Univers
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/jkk.v11i1.369

Abstract

Leprosy is an infectious disease caused by the acid-fast bacillus, namely Mycobacterium lepra. The entry of Mycobacterium leprae into the body can trigger various immune responses. in some individuals, an adequate immune response can prevent the development of this disease, but in other individuals it can develop into a severe form that can result in disability. Leprosy is widespread throughout the world, especially in tropical/subtropical areas. The highest incidence rates are in India, Brazil and India. Eradicating this disease is still a challenge, especially in endemic areas like Indonesia. Therefore, this article aims to review the basic concepts of leprosy, especially in the epidemiological and etiopathogenesis aspects of leprosy, so that it can be used as a reference for further research.
Pendampingan pemanfaatan tanaman herbal pada pasien hipertensi dan diabetes melitus sebagai upaya pencegahan penyakit gagal ginjal di Puskesmas Gandus Palembang Lusiana, Evi; Kurniati, Ardesy Melizah; Harahap, Debby Handayati; Tamzil, Nia Savitri; Parisa, Nita; Adenina,  Masayu Syarinta; Rosdah, Ayesha Augusta; Oktariana, Desi; Pariyana, Pariyana; Azizah, Aida Nur; Islami, Arya Putera
Jurnal Pengabdian Masyarakat: Humanity and Medicine Vol 5 No 1 (2024): Jurnal Pengabdian Masyarakat: Humanity and Medicine
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/Hummed.V5I1.138

Abstract

Hypertension and diabetes mellitus are risk factors for chronic kidney disease. A person diagnosed with hypertension and diabetes mellitus is required to regularly take medication for life, which can lead to side effects of drugs (ESO). This triggers the search for more effective and safer drugs, so many people start to turn to traditional medicine. The main objective of this community service is to increase community knowledge and skills through assistance in cultivating herbal plants such as Sambiloto, Celery, and Ginger. The method of service carried out in this activity is by giving questionnaires before and after the delivery of material with the community in the working area of the Gandus Palembang Health Center. The targets of community service activities are hypertension and diabetes mellitus patients and the community registered in the working area of the Gandus Palembang Health Center as many as 30 participants. The results of the counseling showed that there was an increase in the results of participants who fell into the good category, according to the variables of knowledge, attitude and action respectively 56.7%, 23.3% and 40%.
Pemanfaatan ekstrak air daun karamunting sebagai terapi tambahan pada penderita diabetes mellitus tipe II: edukasi dan pembuatan infusa/ekstrak air karamunting skala rumah tangga Saleh, Muhammad Irsan; Lusiana, Evi; Rofflin, Eddy
Jurnal Pengabdian Masyarakat: Humanity and Medicine Vol 5 No 2 (2024): Jurnal Pengabdian Masyarakat: Humanity and Medicine
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/Hummed.V5I2.139

Abstract

Utilisation of aqueous extract of karamunting leaves as adjunctive therapy in patients with type II diabetes mellitus: education and household-scale production of karamunting water infusion/extracts Diabetes mellitus (DM) is a chronic condition caused by high blood glucose levels due to insulin deficiency or the body's inability to use insulin properly. This community service aims to increase knowledge about Diabetes mellitus and the utilization of herbal plants Karamunting leaves to lower blood sugar. The target of the activity is the community in the working area of the Gandus Palembang Health Center, totaling 30 participants. The method in this service is in the form of socialization of herbal plants of Karamunting leaves to lower blood sugar. The results of this community service are an increase in knowledge and application of herbal plants of Karamunting leaves to reduce blood sugar in the community. The method used was counseling about diabetes mellitus and the benefits of Karamunting leaves, demonstration and assistance in making Karamunting leaf infusion, and evaluation. The results of this community service activity are knowledge about diabetes mellitus increased marked by the activeness of answering questions given and the independent use of Karamunting leaves in handling diabetes mellitus.
Effectiveness of Anthocyanins on Kidney Fibrosis; A Systemic Literature Review Lusiana, Evi; Azizah, Aida Nur; Islami, Arya Putera
Syifa'Medika Vol 15, No 1 (2024): Syifa' MEDIKA: Jurnal Kedokteran dan Kesehatan
Publisher : Faculty of Medicine

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32502/sm.v15i1.7932

Abstract

Renal fibrosis refers to the abnormal accumulation of extracellular matrix during the process of tissue repair. Kidney fibrosis is mostly caused by chronic inflammation, which leads to tissue remodeling and subsequently impairs kidney function, resulting in a reduction in the glomerular filtration rate (GFR). Reduced glomerular filtration rate (GFR) can elevate blood concentrations of urea and creatinine. The chemicals known as anthocyanins possess anti-inflammatory and antioxidant characteristics, hence potentially enhancing renal function. This study was conducted based on a literature review approach, utilizing journal papers published over the past decade (2015-2024) obtained from Pubmed, Science Direct, and Google Scholar. This article aims to represent the diverse scientific investigations made on the efficacy of anthocyanins in enhancing renal function in cases with renal fibrosis. The present study indicates that anthocyanins have a positive impact on kidney function by effectively lowering urea and creatinine levels in individuals with renal fibrosis.
Potential therapy of umbilical cord mesenchymal stem cells (UC-MSC) in renal fibrosis Lusiana, Evi; Legiran, Legiran
Sains Medika: Jurnal Kedokteran dan Kesehatan Vol 14, No 1 (2023): June 2023
Publisher : Faculty of Medicine, Universitas Islam Sultan Agung (UNISSULA), Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/sainsmed.v14i1.22458

Abstract

Renal fibrosis (RF) is a severe kidney pathology defined by myofibroblast anomalies that create extracellular material on the interstitial and glomerular surfaces. The current therapy for treating renal disease has not achieved excellent results. A new theory about applying umbilical cord mesenchymal stem cells (UC-MSC) to treat renal fibrosis and other fibrosis-affected organs has been developed. This review aims to elucidate the role of UC-MSC in the therapy of renal fibrosis and summarize the numerous biological mechanisms involved. A search was undertaken using PubMed and Google Scholar from 2003 to 2021 to gather information regarding the Potential therapy with UC-MSC in renal fibrosis. Multiple studies on rat models of renal fibrosis have demonstrated a considerable improvement in fibrotic kidneys following UC-MSC treatment. It can transfer functional proteins and genetic information to recipient cells that suppress the fibrosis process. UC-MSC is considered a superior approach to MSC for therapeutic purposes due to its straightforward collection, minimum immunogenicity, and solid paracrine potency. The UC-MSC cellular treatment for renal impairment is a feasible option in the future.
Nephrotoxicity and Kidney Fibrosis Due to Gentamicin in Wistar Rats Lusiana, Evi; Saleh, Irsan; Sinaga, Ernawati; Hafy, Zen
Medica Hospitalia : Journal of Clinical Medicine Vol. 10 No. 2 (2023): Med Hosp
Publisher : RSUP Dr. Kariadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36408/mhjcm.v10i2.909

Abstract

Background : Gentamicin is an aminoglycoside used as a treatment for various infections. One of the side effects reported on the use of gentamicin is nephrotoxic. However, there are still many uses of gentamicin that have not been precisely indicated. Objective : To analyze the nephrotoxic effects leading to renal fibrosis due to gentamicin induction in Wistar rats. Methods : This research is an in vivo experimental study, pre- and post-test control group design, conducted in September and October 2022 at the Animal House Laboratory of the Faculty of Medicine, Sriwijaya University, and the Palembang Health Laboratory Center. There were 4 treatment groups: Group I, placebo; Group II, gentamicin-induced (GIG I) at 80 mg/kgBW; Group III, gentamicin-induced (GIG II) at 120 mg/kgBW; and Group IV, gentamicin-induced (GIG III) at 240 mg/kgBW. Gentamicin was administered intraperitoneally for 7 days, to 8 Wistar rats per group. Blood was taken from all Wistar rats in each group on days 0, 3, 7, and 14. The results of the study were tested for normality with the Shapiro-Wilk test and homogeneity with the Levene's test. The ANOVA test and the Post-Hoc test were used to conduct the analysis. Results :  Induction of gentamicin in the GIG I and GIG II groups was significant in increasing the mean creatinine and urea levels on day 0 and day 14 of treatment (p<0.05). In the GIG III group there was a 50% mortality in experimental animals showing a Lethal dose of 50 (LD50) at that dose. Conclusion : GIG I and GIG II have significant nephrotoxic effects in increasing creatinine and urea levels which lead to renal fibrosi.
The Relationship of Knowledge and Attitude to The Behavior of Using Celery as An Antihypercholesterolemia at The Gandus Health Center in Palembang Nia Savitri Tamzil; Debby Handayati Harahap; Evi Lusiana; Nita Parisa; Ayeshah Augusta Rosdah; Syarinta Adenina; Desi Oktariana
Sriwijaya Journal of Medicine Vol. 7 No. 2 (2024): Vol 7, No 2, 2024
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/sjm.v7i2.230

Abstract

Efforts to lower cholesterol levels can be made using traditional medicine. The better a person's knowledge and attitude towards traditional medicine will influence his actions in choosing medicine. This study aims to determine the relationship between knowledge and attitudes regarding traditional medicine on the behavior/actions of choosing celery to treat hypercholesterolemia in the community around the Gandus Health Center, Palembang. Analytical observational research with a cross-sectional design has been carried out at the Gandus Palembang Health Center from 13 to 20 September 2023. 30 respondents met the inclusion criteria. There are still many (43.3%) respondents who have poor knowledge about the use of herbs as anti-hypercholesterolemia, especially celery, while 30% of respondents with a negative attitude towards choosing traditional medicine were found. Based on statistical analysis, the results showed that there was an insignificant relationship between knowledge and behavior (PR = 1.500 (IK95% 0.325 – 6.918); p = 0.896). However, there is a significant relationship between attitudes and behavior (PR = 21.00 (95% CI 2.868 – 153.754); p = 0.002). A person's attitude towards traditional medicine is related to their behavior/actions in choosing celery for the treatment of hypercholesterolemia.
Co-Authors Abda Arif Aisyah Fristania Ditamor Amanda Putri, Khairunnisa Rizqika Amira Azra Arisa Putri Andriani, R.A. Linda Ardesy Melizah Kurniati Aseptianova Aseptianova Ayeshah A Rosdah Az Zahra, Zaviera Azizah, Aida Nur Banun, Syahri Debby Handayati Harahap Debby Handayati Harahap Debby Handayati Harahap Debby Handayati Harahap Desi Oktariana Desi Oktariana Desi Oktariana Eny Rahmawati, Eny Ernawati Sinaga Eskalatin, Khaira Farida Fatmawati, Fatmawati Fifa Argentina Fifa Argentina Fifa Argentina Gita angrini Gita Dwi Prasasty Gita Dwi Prasasty Gita Dwi Prasasty Hafizzanovian, Hafizzanovian Indri Seta Septadina Islami, Arya Putera Ismail, Hidayati Julianus Ake Kemas Ya’kub Rahadiyanto Kessyy Widowati Khairunnisa Rizqika Amanda Putri Komar, Muhammad Hafidh Legiran Legiran Lorenza, Geofanny Luthfiah, Qonita M. T. Kamaluddin Manawan, Efman E.U. Maria Sidabutar, Carolina Mgs. Irsan Saleh, Mgs. Irsan Mikawati Mikawati, Mikawati Muaningsih Muaningsih, Muaningsih Muh. Zukri Malik Muhammad Irsan Saleh Muhammad Reagan Muhammad, Fadhil Nafrah Ardita Nashif, Arkan Abdullah Nia Savitri Tamzil Nia Savitri Tamzil Nita Parisa Nita Parisa Nita Parisa Oktariana, Desi pariyana, Pariyana Phey Liana Phey Liana Pratiwi, Rizky Qonitah, Zahrah Aliyah Rahadiyanto, Kemas Ya’kub Rahardiyanto, Kemas Ya’kub RATNA SARI Resty Ryadinency Ricardo Simanjuntak Rivani, Erizka Rizky Pratiwi Rofflin, Eddy Rosdah, Ayesha Augusta Sabrina, Tia Saleh, M. Irsan Saleh, Muhammad Irsan Sindy Bintang Permata Smaradhna, Safira Sudarto Sudarto Suriyani Suriyani, Suriyani Sutandar, Vivi Hendra Syarinta Adenina Theodorus Theodorus Theodorus Theodorus Theodorus Turridho, Aisya Veny Larasati Wicaksono, Bonanza Abi Wildan Dwi Putra Widodo Zanaria, Rima Zen Hafy