Biology, Medicine, & Natural Product Chemistry
Vol 12, No 2 (2023)

In vivo Alpha-amylase and Alpha-glucosidase Inhibitory Potentials of Panicum maximum Jacq. (Guinea grass) Leaf Extract on Wister Rats

Enin, Godwin Ndarake (Unknown)
Okokon, Jude Efiom (Unknown)
David, Enobong Mfon (Unknown)
Emmanuel, Saviour Elisha (Unknown)
Ekanem, Esther Michael (Unknown)
Antia, Bassey Sunday (Unknown)

Article Info

Publish Date
14 Mar 2024

Abstract

Panicum maximum Jacq. (Guinea grass) a medicinal plant used traditionally in the treatment of diseases including diabetes was evaluated for its effect on alpha amylase and alpha glucosidase enzymes in vivo. The crude ethanol extracts (150, 300 and 450 mg/kg) of P. maximum were investigated using starch, sucrose, glucose and maltose as substrates and acarbose as reference drug. The leaf extract caused significant (p<0.05) reduction in blood glucose levels of the treated rats with the four substrates used. The findings show that the leaf extract of Panicum maximum has the potentials to inhibit alpha amylase and alpha glucosidase in rats.

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Journal Info
Biology, Medicine, & Natural Product Chemistry
Website

Abbrev

BIOMEDICH

Publisher

Universitas Islam Negeri Sunan Kalijaga Yogyakarta

Subject

Biochemistry, Genetics & Molecular Biology Medicine & Pharmacology Public Health

Description

BIOLOGY, MEDICINE, & NATURAL PRODUCT CHEMISTRY, this journal is published to attract and disseminate innovative and expert findings in the fields of plant, animal, and microorganism secondary metabolite, and also the effect of natural product on biological system as a reference source for ...