FITOFARMAKA: Jurnal Ilmiah Farmasi
Vol 13, No 2 (2023): FITOFARMAKA: Jurnal Ilmiah Farmasi

Potential of Malang Robusta Coffee Beans as Anti-breast Cancer In-Vitro

Utami, Novi Fajar (Unknown)
Elya, Berna (Unknown)
Hayun, Hayun (Unknown)
Kusmardi, Kusmardi (Unknown)
Nur, Syamsu (Unknown)
Fajriati, Annisa (Unknown)



Article Info

Publish Date
02 Jan 2024

Abstract

Robusta coffee from Malang Regency, East Java is one of the superior products of the largest coffee-producing region in Indonesia. The coffee has high antioxidants. The component that acts as an antioxidant is the tannin content, and these tannins are also anti-cancer. Using the UV-Vis spectrophotometry method the tannin content in Malang Robusta coffee beans is known and then to measure its ability as an anticancer in-vitro against breast cancer cells using MCF-7.  The results showed that the tannin contained in Malang Robusta coffee bean extract was 2.81 % and inhibited MCF-7 at 400 µg/mL, it has potential as an anticancer with an inhibition value of 68.88 %. Therefore, the use of Robusta coffee from Malang at this concentration can be used as an anti-breast cancer agent.

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Journal Info

Abbrev

fitofarmaka

Publisher

Subject

Chemistry Medicine & Pharmacology

Description

FITOFARMAKA mempublikasikan artikel yang berkaitan dengan farmasi, Kimia Farmasi, dan bidang Fitokimia serta akan dipublikasikan secara online. Publikasi secara elektronik akan menambah kekayaan informasi dan pengetahuan ilmiah terutama dari penelitian. Jurnal ini diterbitkan dua kali setahun, ...