Journal of Scientific Research, Education, and Technology
Vol. 3 No. 2 (2024): Vol. 3 No. 2 2024

Effect Of Anting-Anting Leaf Extract (Acalypha Indica L.) On Lowering Blood Glucose Rats (Rattus Norvegicus) Induced By Sukrosa

solihah, Riyadatus (Unknown)
Umar Rahmadani, Rizal (Unknown)
Kristina, Metta (Unknown)



Article Info

Publish Date
26 May 2024

Abstract

Anting-anting leaves (Acalypha indica L.) are weeds that have various properties, one of which is as a lowering blood glucose levels. The chemical content contained in the form of flavonoids that function as inhibitors of α-glucosidase, maltase, α-amylase enzymes, tannin substances are also known to function as astrigents that can inhibit glucose intake is not excessive. The purpose of this study is to determine whether there is an effect of anting-anting leaf extract (Acalypha indica L.) on reducing blood glucose levels in rats (Rattus norvegicus) induced by sucrose. This research used 20 rats (Rattus norvegicus) as test animals which were divided into 5 groups. The group consisted of negative control group, positive control and 3 dose groups. The doses used were 500 mg/kgBB, 1000 mg/kgBB and 1200 mg/kgBB. Mice were made hyperglycemia with sucrose induction which was then given anting-anting leaf extract (Acalypha indica L.) according to lower glucose levels in mice. The results obtained were continued with the two-way ANOVA test and obtained significant results indicated by p < 0.05 (0.005) which showed there was a significant effect of anting-anting leaf extract (Acalypha indica L.) on reducing blood glucose levels in sucrose-induced rats (Rattus norvegicus). Significant results were continued with the post hoc test and obtained significant results.

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Journal Info

Abbrev

jrest

Publisher

Subject

Computer Science & IT Economics, Econometrics & Finance Education Engineering Social Sciences

Description

FOCUS AND SCOPE JSRET (Journal of Scientific Research, Education, and Technology) encourages scientific and technological research, particularly with regard to Indonesia, but not just in terms of authorship or regional coverage of current issues. Scientists, instructors, senior researchers, project ...