<![CDATA[Anemia is currently still a problem and suffered by many adolescent girls, especially in developing countries. The prevalence of anemia in adolescent girls in Indonesia based on Riskesdas 2018 data is 32%, which means that 3-4 out of 10 adolescent girls experience anemia. In some parts of Indonesia the prevalence of anemia reaches 60%. This study aimed to determine the difference in iron supplementation in adolescent girls with intermittent anemia compared to routine supplementation against the increase in hemoglobin levels and side effects caused. Research methods used quasi experiment with control group. Sampling used by stratified random sampling technique. Data collection was carried out by measuring hemoglobin levels of adolescent girls before and after intervention in both groups. The independent t-test showed that the significance value in the intermittent group and routine group was 0.334, which means that the variation in both groups was the same (>0.05). The results of the t test obtained a p value of 0.379 which means that between giving iron supplementation both intermittently and routinely did not provide a difference in the results of hemoglobin levels in adolescent girls. This shows that intermittent iron supplementation can still increase hemoglobin levels. Giving iron supplementation can be given intermittently or routinely both can increase hemoglobin levels in adolescent girls with anemia. Consideration of giving iron supplementation can be considered on the side effects that may be caused so that intermittent administration can be an alternative to continue to increase hemoglobin levels with fewer side effects felt.]]>
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