IJOEP : International Journal of Ecophysiology
Vol. 6 No. 2 (2024): International Journal of Ecophysiology

Hepatoprotective effects of ethanol extract of mobe leaves/eeml (artocarpus lacucha buch-ham.) against carbon tetrachloride induced hepatotoxicity in rats: English

Lubis, Meiva Amelia (Unknown)
Dalimunthe, Aminah (Unknown)
Sitorus, Panal (Unknown)
Satria, Denny (Unknown)



Article Info

Publish Date
29 Sep 2024

Abstract

This study evaluates the protective effects of ethanol extract of mobe leaves (Artocarpus lacucha Buch-Ham.) on ALT, AST, and bilirubin levels in rats induced with carbon tetrachloride (CCl4) on Liver. The ethanol extract was prepared by maceration using 96% ethanol. Results showed that administering 400 mg/kg BW of the extract significantly reduced total bilirubin, ALT, and AST levels in CCl4-induced rats. Phytochemical screening revealed bioactive compounds like flavonoids, alkaloids, tannins, saponins, triterpenoids, and glycosides, which are potential antioxidants and hepatoprotective agents. The study concludes that mobe leaf extract has potential as a therapeutic agent to protect the liver from toxic damage. The significant contribution of this research is providing a scientific basis for using mobe leaf extract as a natural hepatoprotective agent, highlighting its potential for safe and effective herbal medicine. Further research and clinical trials are recommended.

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Journal Info

Abbrev

ijoep

Publisher

Subject

Agriculture, Biological Sciences & Forestry

Description

International Journal of Ecophysiology (IJOEP) is a peer-reviewed biannual journal (February and July) published by TALENTA Publisher and organized by Faculty of Mathematics and Natural Sciences, Universitas Sumatera Utara (USU) as an open-access journal. It welcomes full research articles in the ...