Article Per Year (5 Year)
p-Index From 2020 - 2025
2.986
P-Index
This Author published in this journals
All Journal Dentika Dental Journal Majalah Obat Tradisional Dental Journal (Majalah Kedokteran Gigi) Viva Medika: Jurnal Kesehatan, Kebidanan dan Keperawatan Indonesian Journal of Pharmaceutical and Clinical Research IJOEP : International Journal of Ecophysiology International Journal Of Science, Technology & Management (IJSTM) Indonesian Journal of Applied Research (IJAR) Proceeding ISETH (International Summit on Science, Technology, and Humanity) Jurnal ABDIMAS MUTIARA
Denny Satria, Denny
Unknown Affiliation
Aerospace Engineering Agriculture, Biological Sciences & Forestry Automotive Engineering Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Control & Systems Engineering Decision Sciences, Operations Research & Management Dentistry Earth & Planetary Sciences Education Electrical & Electronics Engineering Energy Engineering Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Mechanical Engineering Medicine & Pharmacology Nursing Public Health Social Sciences Transportation Other

Published : 19 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 19 Documents
Search

 1   2 
Hyaluronic Acid And Its Role In Periodontal Healing: Asam Hialuronat dan Peranannya Dalam Penyembuhan Periodontal Wulandari, Pitu; Amalia, Martina; Budi; Simanjuntak, Rio; Satria, Denny
Dentika: Dental Journal Vol. 25 No. 1 (2022): Dentika Dental Journal
Publisher : TALENTA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/dentika.v25i1.6811

Abstract

Hyaluronic acid is known as hyaluronan or hyaluronate, which has the function of increasing the mediator of periodontal regeneration. Hyaluronate acid has many roles in the early stages of inflammation, such as providing a structural framework through the interaction of hyaluronate with fibrin clots that modulate host inflammation and infiltration of the extracellular matrix of cells at the wound site so that this material becomes a therapeutic material used in various fields, especially in the field of periodontics. All periodontal tissues have shown the presence of hyaluronate, which is specifically concentrated in non-mineral tissues such as gingiva and periodontal ligament, which affects the growth, development, and repair of tissues in periodontal disease. The role of hyaluronic acid in periodontal healing will be discussed in this article.
Antioxidant activity of 1.3-bis(p-hydroxyphenyl)urea by CUPRAC and FRAP methods Satria, Denny; Rifda Amaliya Ma’ruf; Syukur Berkat Waruwu; Urip Harahap; Hari Purnomo4
Indonesian Journal of Pharmaceutical and Clinical Research Vol. 6 No. 1 (2023): Indonesian Journal of Pharmaceutical and Clinical Research
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/idjpcr.v6i1.17768

Abstract

An imbalance in the number of free radicals produced in the body can result in oxidative stress. Excessive oxidative stress can lead to chronic inflammation, which in turn can lead to most chronic diseases. Inflammation is related to oxidation through increased reactive oxidative stress, which can target modulators associated with inflammation, such as inflammatory cytokines. Antioxidants can inhibit or stop oxidation by protecting the body and neutralizing free radicals. 1.3-bis(p-hydroxyphenyl)urea is a modification of p-aminophenol and has hepatotoxic side effects such as those caused by acetaminophen. This compound can relieve pain, is anti-inflammatory, and has fewer side effects. This research was conducted to evaluate the antioxidant activity of 1.3-bis(p-hydroxyphenyl)urea using the CUPRAC (Cupric Ion Reducing Antioxidant Capacity) method and the FRAP (Ferric Reducing Antioxidant Power) method. The results of the CUPRAC method research show that the 1.3-bis(p-hydroxyphenyl)urea compound has an IC50 value of 4.40 ± 0.07 μg/mL. Meanwhile, the FRAP method was 29.36 ± 1.20 μg/mL. Apart from suppressing inflammation, this compound has the potential to be an antioxidant compound.
Immunomodulator Activity Test of Curucuminoid Extract Derived from Turmeric Rhizome (Curcuma domestica Val.) In VCO On Rats Injected with Staphylococcus aureus Against an Increase in The Concentration of Leucocyte and Its Components. Pratiwi, Indah; Yuandani; Putra, Effendy De Lux; Satria, Denny
International Journal of Science, Technology & Management Vol. 4 No. 4 (2023): July 2023
Publisher : Publisher Cv. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

One of the medicinal Zingiberaceae plants which is regularly used by the society as a traditional remedy is turmeric rhizome. The pharmacological properties of turmeric rhizome include anti-inflammatory, anti-immunodeficiency, anti-viral. Anti-bacterial, anti-fungal, anti-oxidant, anti-carcinogenic, and anti-infectious. This study aimed to identify the immunomodulator activity of curcuminoid extract of turmeric rhizome against the increase of leucocyte and its components, lymphocyte and neutrophil in white Galur Wistar rats that had been injected with Staphylococcus aureus. These test animals were given curcuminoid extract in VCO 100 mg/ml on a dosage of 1 ml, 0,5 ml, 0,25 ml curcuminoid powder 200 mg/kg body weight. Curcuminoid was suspended in Na CMC0,5%, Levamisole 25 mg/kg of body weight suspended in Na CMC 0,5%, VCO 1 ml. For the negative control, merely Na CMC 0,5% was given. The extract was orally given daily for 14 days. On the 4th day, Staphylococcus aureus was injected intra-peritoneally. The rats’ blood was then drawn from the heart and was observed to calculate the volume of the leucocytes, lymphocyte, and neutrophil which was conducted using flow cytometry.The findings suggested that there was a significant difference between the immunomodulatory activity of the curcuminoid extract in VCO at the doses of 1 ml, 0,5 ml, 0,25 ml on the increase in leucocyte, lymphocyte, and neutrophil compared to that of the negative control.Therefore, the findings of this study indicated that the extracts of curcuminoid in VCO could increase the number of leucocytes, lymphocytes, and neutrophils. Thus, the curcuminoid extract of turmeric rhizome in VCO potentially possessed immunomodulatory activity.
Antioxidant Activity of Hydroalcoholic Extract of Puguntano Herbs and Andaliman Fruits by Cuprac Methods Satria, Denny; Dalimunthe, Aminah; Sitorus, Panal; Waruwu, Syukur Berkat; Vadhila, Mumtaz; Wahyu, Muhammad
Majalah Obat Tradisional Vol 29, No 2 (2024)
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/mot.90337

Abstract

Free radical damage to the body can be prevented and repaired using antioxidants. Various natural ingredients native to Indonesia contain antioxidants, which are needed to improve people's health at an affordable cost. Puguntano (Picria fel-terrae) and Andaliman (Zanthoxylum acanthopodium DC.) are natural ingredients that can be used as antioxidants. This research determined the antioxidant activity and differences in IC50 values of hydroalcoholic extracts from Puguntano (Picria fel-terrae Lour) herbs and Andaliman (Zanthoxylum acanthopodium Fruits). Hydroalcoholic extracts were prepared by maceration using 90%, 80%, 70%, 60% and 50% ethanol. Antioxidant capacity was measured using the CUPRAC method, and quercetin was used as a positive control. The results were showed that the IC50 value for hydroalcoholic extracts of Puguntano herbs (27.02 ± 0.15 µg/mL, 25.94 ± 0.22 µg/mL, 25.12 ±0.15 µg/mL, 22.07 ± 0.23 µg/mL, and 23.86 ±0.18 µg/mL) and for Andaliman fruits (41.65 ± 0.30 µg/mL, 36.59 ± 0.40 µg/mL, 34.13 ± 0.44 µg/mL, 25.46 ± 0.30 µg/mL, 25.39 ± 0.30 µg/mL) respectively and quercetin 2.21 ± 0.02 µg/mL. Hydroalcoholic extracts of Puguntano herbs and Andaliman fruits have antioxidant activity, with each concentration having an IC50 of less than 50 µg/mL. The test sample's antioxidant activity is indicated by its lower IC50 value.
Hepatoprotective effects of ethanol extract of mobe leaves/eeml (artocarpus lacucha buch-ham.) against carbon tetrachloride induced hepatotoxicity in rats: English Lubis, Meiva Amelia; Dalimunthe, Aminah; Sitorus, Panal; Satria, Denny
International Journal of Ecophysiology Vol. 6 No. 2 (2024): International Journal of Ecophysiology
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/ijoep.v6i2.17505

Abstract

This study evaluates the protective effects of ethanol extract of mobe leaves (Artocarpus lacucha Buch-Ham.) on ALT, AST, and bilirubin levels in rats induced with carbon tetrachloride (CCl4) on Liver. The ethanol extract was prepared by maceration using 96% ethanol. Results showed that administering 400 mg/kg BW of the extract significantly reduced total bilirubin, ALT, and AST levels in CCl4-induced rats. Phytochemical screening revealed bioactive compounds like flavonoids, alkaloids, tannins, saponins, triterpenoids, and glycosides, which are potential antioxidants and hepatoprotective agents. The study concludes that mobe leaf extract has potential as a therapeutic agent to protect the liver from toxic damage. The significant contribution of this research is providing a scientific basis for using mobe leaf extract as a natural hepatoprotective agent, highlighting its potential for safe and effective herbal medicine. Further research and clinical trials are recommended.
PENYULUHAN PEMBUATAN SEDIAAN SABUN CUCI TANGAN CAIR DARI MINYAK KELAPA MURNI (Virgin coconut oil) Satria, Denny; Munthe, Alfian Rejekinta; Brahmana, Nettietalia Br
Jurnal Abdimas Mutiara Vol. 3 No. 1 (2022): JURNAL ABDIMAS MUTIARA (In Press)
Publisher : Universitas Sari Mutiara Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Sabun cuci tangan merupakan cairan yang diformulasikan untuk membantu membersihkan tangan dari kotoran dan kuman. Sabun dalam sediaan cair saat ini banyak diproduksi karena penggunaannya yang lebih praktis dibandingkan sabun batang. Minyak kelapa hasil olahan petani dengan proses tradisional umumnya hanya digunakan sebagai minyak goreng. Padahal minyak kelapa juga bisa dimanfaatkan sebagai bahan baku dalam pembuatan sabun cair. VCO terbuat dari daging kelapa segar. Tujuan penyuluhan ini untuk memberikan pemanfaatan minyak kelapa murni dapat diolah menjadi sediaan sabun cuci tangan cair. Hasil pelaksaan ini pada masyrakat dalam bentuk informasi dan edukasi pemanfaatan minyak kelapa murni sebagai sediaan sabun cuci tangan cair. Setelah melaksakan kegiatan pelatihan ini, masyarakat lebih mengetahui bahwa minyak kelapa murni yang selama ini hanya dijadikan sebagai minyak goreng ternyata sangat bagus dibuat menjadi sediaan sabun cuci tangan cair.
PENYULUHAN DAN BUDIDAYA SECARA HIDROPONIK BUAH STROBERI (Fragaria x ananassa Duschesne) YANG MENGANDUNG VITAMIN C di RUMAH KABANJAHE Manuppak Irianto, Manuppak Irianto; Satria, Denny; Sitorus, Binsar
Jurnal Abdimas Mutiara Vol. 2 No. 1 (2021): JURNAL ABDIMAS MUTIARA
Publisher : Universitas Sari Mutiara Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Tanaman stroberi (Fragaria x ananassa Duch.) adalah salah satu tanaman buah di Indonesia dengan daya pikat warna buah merah mencolok, bentuk menarik, serta rasa manis dan segar serta kelebihan lainnya yaitu stroberi sumber senyawa bioaktif yang penting karena mengandung kadar vitamin C, folat dan unsur fenolik yang tinggi. Stroberi memiliki nilai ekonomi tinggi sehingga prospek untuk dikembangkan di daerah dataran rendah. Budidaya stroberi di dataran rendah untuk skala produksi masih jarang dilakukan disebabkan adanya kendala faktor iklim seperti suhu dan intensitas radiasi matahari yang tinggi. Budidaya secara hidroponik, stroberi dapat ditanam dengan pola penanaman vertikal (vertikultur), stroberi yang dihasilkan lebih segar, bersih higienis sehingga memiliki nilai ekonomis tinggi, perawatan tanaman relatif mudah, membutuhkan tenaga kerja yang lebih sedikit, tanaman relatif terhindar dari hama, jamur dan penyakit, ramah lingkungan, perawatan tanaman lebih terkontrol, penggunaan pupuk lebih hemat, efektif dan efisien. Kesimpulan bahwa penyuluhan budidaya buah stroberi secara hidroponik terlaksana sesuai pelaksanaan dan rencana, mendapat sambutan baik dari para petani dan masyrakat sekitar mendapatkan informasi serta pengetahuan dan menerapkan penanaman buah storberi secara hidroponik dilingkungan rumah masing- masing.
PEMANFAATAN TANAMAN OBAT INDONESIA UNTUK PENCEGAHAN DAN PENANGGULANGAN PENYAKIT HIPERTENSI PADA PUSAT KESEHATAN MASYARAKAT (PUSKESMAS) GLUGUR DARAT Satria, Denny; Manurung, Kesaktian; Tarigan, Yenni Gustiani
Jurnal Abdimas Mutiara Vol. 2 No. 2 (2021): JURNAL ABDIMAS MUTIARA
Publisher : Universitas Sari Mutiara Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Program pengabdian kepada masyarakat mengenai pemanfaatan tanaman obat dan obat tradisional untuk pencegahan dan penanggulanagan penyakit hipertensi telah dilakukan di berbagai daerah. Tujuan pengabdian ini adalah untuk memberikan edukasi tentang tanaman obat keluarga untuk pertolongan pertama pada hipertensi. Metode yang digunakan dalam pengabdian kepada masyarakat ini adalah metode yang digunakan untuk pengabdian kepada masyarakat ini adalah menggunakan metode presentasi dan menunjukkan secara langsung samle tumbuhan yang berpotensi untuk mengobati dan mencegah penyakit hipertensi. Kesimpulan yang dapat diambil setelah kegiatan penyuluhan ini adalah bertambahnya pengetahuan dan keterampilan peserta khususnya orang tua tentang penyakit hipertensi. Faktor-faktor penyebab hipertensi danc ara pengecahan atau penganggulangan penyakit hipertensi selain itu peserta mampu menetapkan pemeliharaan tanaman toga keluarga dan mengonsumsi tanaman obat dalam mengatasi penyakit-penyakit seperti hipertensi. Saran yang dapat diberikan agar masyarakt khususnya orang tua dengan usia diatas 40 tahun lebih cerdas dalam memafaatkan pekarangan rumah untuk menanam dan memberikan tumbuhan sekitar yag berpotensi sebagai obat
PENYULUHAN PENTINGNYA LILIN AROMATERAPI DARI DAUN MINT DAN KULIT JERUK UNTUK MEMBANTU MEMBANGKITKAN SEMANGAT DAN MENYEGARKAN Satria, Denny; Taruli Rohana Sinaga; Ruth Christiani N Daely
Jurnal Abdimas Mutiara Vol. 1 No. 2 (2020): JURNAL ABDIMAS MUTIARA
Publisher : Universitas Sari Mutiara Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Aromaterapi berasal dari tanaman yang mudah menguap dan memiliki minyak atsiri. Minyak atsiri ini tidak hanya bisa untuk mengobati penyakit namun dapat juga untuk memperbaiki suasana hati ataupun mood. Minyak atsiri dari daun mint dan kulit jeruk memliki efek yang menyegarkan dan membangkitkan semangat. Tujuan dari penyuluhan ini adalah memberikan infomasi tentang manfaat dari lilin aromaterapi daun mint dan kulit jeruk yang dapat menyegarkan dan memberi semangat.
Green Synthesis of Silver Nanoparticles Using Extract of Kluwih Leaves (Artocarpus camansi Blanco.) by Microwave-Assisted Irradiation and Their Antibacterial Properties Siregar, Nina Ashariani; Putra, Effendy De Lux; Sinaga, Siti Morin; Satria, Denny; Waruwu, Syukur Berkat
Indonesian Journal of Applied Research (IJAR) Vol. 5 No. 3 (2024): Indonesian Journal of Applied Research (IJAR)
Publisher : Universitas Djuanda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30997/ijar.v5i3.540

Abstract

Nanoparticles are particles measuring 1-100 nm that were synthesized using metals, and silver was a commonly used metal because of its potential as an antibacterial agent. Physical and chemical methods were often used in synthesis but are less environmentally friendly. Alternatively, biological processes that utilize phytochemical compounds as reducing agents are preferred. One of the plants rich in phytochemical compounds was kluwih leaves (Artocarpus camansi Blanco). This study aimed to synthesize silver nanoparticles (AgNPs) mediated by kluwih leaves using microwave irradiation. Characterization of nanoparticles was carried out by visual observation and using UV-Vis spectrophotometry. Antibacterial activity was evaluated by determining MIC (Minimum Inhibitory Concentration) and MBC (Minimum Bactericidal Concentration), followed by examining DNA and protein leakage and biofilm formation using a microdilution method against S. epidermidis and P. aeruginosa. The results showed that AgNPs from kluwih leaves had been successfully formed and could be used as reducing agents in AgNPs biosynthesis. Visual color changed, and analysis of UV-Vis spectrophotometry showed peaks at 441 nm. The results of the antibacterial evaluation showed MIC 1.90 µg/ml (S. epidermidis) and 7.80 µg/ml (P. aeruginosa) also caused cell leakage and reduced biofilm formation significantly at a concentration of 1/2 MIC. These results were promising for further development in future research.
Co-Authors Amalia, Martina Aminah Dalimunthe Brahmana, Nettietalia Br Budi Budi Diana Sofia Hanafiah Dohude, Gostry Aldica Effendy De Lux Putra, Effendy De Lux Estefania, Kaban Vera Harahap, Nurul Izzatunna Jhirah Hari Purnomo4 Haro, Ginda Hasibuan, Poppy Anjelisa Zaitun Indah Pratiwi Jansen Silalahi Lubis, Arga Lubis, Meiva Amelia lubis, muhammad fauzan Manuppak Irianto, Manuppak Irianto Manurung, Kesaktian Muhammad Wahyu, Muhammad Munthe, Alfian Rejekinta Nasri Nasri, Nasri Octora, Debi Dinha Olivia Avriyanti Hanafiah Pitu Wulandari Putri, Maharani Syahnia Rifda Amaliya Ma’ruf Rosidah Rosidah Rosidah Rosidah, R Ruth Christiani N Daely Said Aldi Palevi Simanjuntak, Rio Siregar, Nina Ashariani Siti Bahirrah Siti Morin Sinaga Sitorus, Binsar Sitorus, Panal Sumaiyah, Sumaiyah Syukur Berkat Waruwu Tarigan, Yenni Gustiani Taruli Rohana Sinaga Urip Harahap Vadhila, Mumtaz Waruwu, Syukur Berkat Widjaja, Sri Suryani Yuandani Yuandani, Y Yuwanda, Cindy Zuhairiah Nasution, Zuhairiah