Jurnal Farmasi Galenika
Vol 7 No 3 (2020): Jurnal Farmasi Galenika Vol 7 No 3

ANTIOXIDANT ACTIVITY OF VARIOUS EXTRACTS OF JARAK TINTIR (Jatropha multifida L.) STEM, PHENOLIC AND FLAVONOID CONTENT

Syam, Akhirul Kahfi (Unknown)
Windyaswari, Ari Sri (Unknown)
Ratnawati, Julia (Unknown)



Article Info

Publish Date
07 Dec 2020

Abstract

Background: Jarak tintir (Jatropha multifida L.) was identified as one of family Euphorbiaceae and used by Indonesian people as traditional medicine. This study aimed to measure IC50 of inhibition DPPH as free radicals and make statistical analysis of flavonoid and phenolic content and correlation with their IC50 of free radicals. Methods: Hot continuous extraction was done with Soxhlet apparatus using various polarity solvents (n-hexane, ethyl acetate, and methanol). Results: Methanol extract had the lowest IC50 32.26 ± 0.37 µg/mL of DPPH inhibition activity. Ethyl acetate extract had highest phenolic and highest flavonoid content with 35.21 ± 1.50 mg TAE/g extract and 49.41 ± 1.65 mg QE/g extract. Conclusion: Flavonoid and phenolic content in extracts had linier correlation with their IC50 of inhibition free radicals.

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Journal Info

Abbrev

jfg

Publisher

Subject

Medicine & Pharmacology Public Health

Description

The aim of JFG is to become a media for the publication of articles on Pharmaceutical and related practice-oriented subjects in the pharmaceutical sciences and technology. The scope of the journal is Pharmaceutical sciences, its research and its application. The journal aims to cover the latest ...