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All Journal Journal of Food and Pharmaceutical Science Elkawnie Journal of Islamic Pharmacy Jurnal Buana Farma Jurnal Abdimas Kartika Wijayakusuma AJAD : Jurnal Pengabdian kepada Masyarakat Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Room of Civil Society Development Riset Informasi Kesehatan Journal of Food and Pharmaceutical Sciences kawanad Kartika : Jurnal Ilmiah Farmasi Medical Sains : Jurnal Ilmiah Kefarmasian Jurnal Farmasi Galenika Room of Civil Social Development Journal of Pharmascience
Ari Sri Windyaswari
Universitas Jenderal Achmad Yani
Aerospace Engineering Arts Humanities Automotive Engineering Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Control & Systems Engineering Education Electrical & Electronics Engineering Engineering Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

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Identification of the Secondary Metabolites and Characterization of Lagerstroemia Loudonii T. & B. Faramayuda, Fahrauk; Hermanto, Faizal; Windyaswari, Ari Sri; Riyanti, Soraya; Nurhayati, Viola Aditya
Journal of Islamic Pharmacy Vol 6, No 1 (2021): J. Islamic Pharm.
Publisher : Universitas Islam Negeri Maulana Malik Ibrahim Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18860/jip.v6i1.11351

Abstract

Bungur  (Lagerstroemia loudonii T. B) is a type of plant widely grown in Indonesia and can be found in teak forests, mixed forests, and is found as ornamental plants or protective trees on the roadside. In the fruit section, Lagerstroemia loudonii is used as antituberculous and antimalarial. On the bark, the part is used as antidiarrheal. Based on some parts of the Lagerstroemia loudonii  plants' activity data, this plant has the potential to be developed into traditional medicine. Standardized traditional medicine material is necessary to identify efficacious compounds and characterization in some parts of Lagerstroemia loudonii. The purpose of this research is to develop Lagerstroemia loudonii into traditional herbal medicine or standardized herbal medicine. Identification of efficacious compounds and characterization of crude leaf drugs, bark, stems, and fruit of Lagerstroemia loudonii. The phytochemical screening phase of the crude drugs of leaves, bark, stems, and fruit ofLagerstroemia loudonii against includes examining alkaloids, flavonoids,  quinones, tannins, polyphenols, saponins, steroids and triterpenes, monoterpenoids and sesquiterpenoids. The determination of the characteristics of raw material carried out includes nonspecific parameters. Nonspecific parameters are the determination of total ash content, water-soluble ash content, acid insoluble ash content. each experiment was carried out three times and calculated the average yield and deviation.  Identification results of the class of efficacious compounds in some parts of the Lagerstroemia loudonii  plant are on the leaves and fruits containing alkaloids, flavonoids, saponins, quinones, tannins, polyphenols, monoterpenoids, and sesquiterpenoids as well as steroids and triterpenoids. At the bark and stem, the bark contains alkaloids, flavonoids, saponins, quinones, tannins, polyphenols, monoterpenoids, and sesquiterpenoids. Characterization results of Lagerstroemia loudonii  leaf extract total ash content 4.45 ± 0.30% w/w, water-soluble ash content 4.08 ± 0.27% w/w, acid insoluble ash content 0.59 ± 0.06% w/w, the extract specific gravity was 0.59 ± 0.063. Lagerstroemia loudonii  stem bark extract, total ash content 1.94 ± 0.12% w/w, water-soluble ash content 1.47 ± 0.03% w/w, acid insoluble ash content 0.24 ± 0.02% w/w, the extract specific gravity is 0.82 ± 0.01. Lagerstroemia loudonii  stem extract, total ash content3.18 ± 0.16% w/w, water-soluble ash content 2.36 ± 0.38% w/w, acid insoluble ash content 0.43 ± 0.07% w/w, extract specific grafity 0.81 ± 0.01. Lagerstroemia loudonii  fruit extract, total ash content 11.45 ± 1.16%w/w, water-soluble ash content 10.1 ± 1.49% w/w, acid insoluble ash content 1.46 ± 0.88% w/w,extract specific grafity 0.81 ± 0.01. Based on phytochemical screening data and the characterization of bungur plants potential to be developed into raw materials for traditional medicineKeywords: Lagerstroemia loudonii, secondary metabolite, raw material characterization
Identification of Secondary Metabolites Compounds From Nampu (Homalomena rosrata Griff.) Fahrauk Faramayuda; Luthfi Fauziah; Ari Sri Windyaswari; Julia Ratnawati
Elkawnie: Journal of Islamic Science and Technology Vol 8, No 1 (2022)
Publisher : Universitas Islam Negeri Ar-Raniry Banda Aceh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22373/ekw.v8i1.9511

Abstract

Abstract: Nampu (Homalomena rosrata Griff.) is traditionally used to increase sexual activity for men. However, the lack of scientific information on the phytochemical content of Nampu plants needs further research on the secondary metabolite compounds for isolation and identification purposes. The phytochemical screening of raw material, ethanol extract, and water fraction shows positive results for flavonoid, tannin, polyphenol, quinone, monoterpenoid-sesquiterpenoid, and steroid-triterpenoid groups. The chloroform fractions were monitored by the thin-layer chromatography (TLC) method with the addition of KOH 5%. The results showed a blue spot under UV light at 365 nm after the addition of KOH 5%. The fraction was purified by a preparative thin-layer chromatography method (TLC-P), while the isolates' purity was tested by the two-dimensional TLC method and TLC with three different phases of mobile phases. The results of the analysis with the spectrophotometer UV-Visible showed the wavelength of 278.8 nm and 213.2 nm. In addition, the functional group analysis using the I.R. spectrometer showed O.H. stretch at wave numbers 3419.79 cm-1, aromatic C-H at wave number 2922.16 cm-1, C = O at the wave number 1672.28 cm-1, strain C = C aromatic at the wave number 1585.49 cm-1. Based on TLC and spectrophotometric data, the isolates were coumarin compounds.Abstrak: Nampu (Homalomena rosrata Griff.) secara tradisional digunakan untuk meningkatkan aktivitas seksual pria. Namun, kurangnya informasi ilmiah tentang kandungan fitokimia tanaman Nampu, perlu penelitian lebih lanjut tentang senyawa metabolit sekunder untuk tujuan isolasi dan identifikasi. Penapisan fitokimia bahan baku, ekstrak etanol dan fraksi air menunjukkan hasil positif untuk golongan flavonoid, tanin, polifenol, kuinon, monoterpenoid-seskuiterpenoid, dan steroid-triterpenoid. Fraksi kloroform dipantau dengan metode kromatografi lapis tipis (KLT) dengan penambahan KOH 5%. Hasilnya menunjukkan bercak berwarna biru di bawah lampu U.V. 365 nm. Fraksi dimurnikan dengan metode kromatografi lapis tipis preparatif (KLT-P), sedangkan kemurnian isolat diuji dengan metode KLT dua dimensi dan KLT dengan tiga fase gerak yang berbeda. Hasil analisis dengan spektrofotometer UV-Visible menunjukkan panjang gelombang 278,8 nm dan 213,2 nm. Selain itu, analisis gugus fungsi menggunakan spektrometer infra merah menunjukkan adanya gugus OH, regangan pada bilangan gelombang 3419,79 cm-1, C-H aromatik pada bilangan gelombang 2922,16 cm-1, C = O pada bilangan gelombang 1672,28 cm-1, regangan C = C aromatik pada bilangan gelombang 1585,49 cm-1. Berdasarkan data KLT dan spektrofotometri, diduga isolat merupakan golongan senyawa kumarin.Nampu (Homalomena rosrata Griff.) secara tradisional digunakan untuk meningkatkan aktivitas seksual pria. Namun, kurangnya informasi ilmiah tentang kandungan fitokimia tanaman Nampu, perlu penelitian lebih lanjut tentang senyawa metabolit sekunder untuk tujuan isolasi dan identifikasi. Penapisan fitokimia bahan baku, ekstrak etanol dan fraksi air menunjukkan hasil positif untuk golongan flavonoid, tanin, polifenol, kuinon, monoterpenoid-seskuiterpenoid, dan steroid-triterpenoid. Fraksi kloroform dipantau dengan metode kromatografi lapis tipis (KLT) dengan penambahan KOH 5%. Hasilnya menunjukkan bercak berwarna biru di bawah lampu U.V. 365 nm. Fraksi dimurnikan dengan metode kromatografi lapis tipis preparatif (KLT-P), sedangkan kemurnian isolat diuji dengan metode KLT dua dimensi dan KLT dengan tiga fase gerak yang berbeda. Hasil analisis dengan spektrofotometer UV-Visible menunjukkan panjang gelombang 278,8 nm dan 213,2 nm. Selain itu, analisis gugus fungsi menggunakan spektrometer infra merah menunjukkan adanya gugus OH, regangan pada bilangan gelombang 3419,79 cm-1, C-H aromatik pada bilangan gelombang 2922,16 cm-1, C = O pada bilangan gelombang 1672,28 cm-1, regangan C = C aromatik pada bilangan gelombang 1585,49 cm-1. Berdasarkan data KLT dan spektrofotometri, diduga isolat merupakan golongan senyawa kumarin.
Traditional uses, phytochemistry, pharmacology activity and plant tissue culture of ficus carica l. (a mini review) Fahrauk Faramayuda; Sigid Pamungkas Wicaksono; Akhirul Kahfi Syam; Soraya Riyanti; Ari Sri Windyaswari; Yeni Karlina; Elfahmi Elfahmi
Riset Informasi Kesehatan Vol 11 No 1 (2022): Riset Informasi Kesehatan
Publisher : Sekolah Tinggi Ilmu Kesehatan Harapan Ibu Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (276.464 KB) | DOI: 10.30644/rik.v11i1.537

Abstract

Ficus carica L. or Figs plants are plants originating from the Middle East and the Mediterranean region, which then spread to various parts of the world through explorers who try to plant in various countries. Figs plants can grow in various habitats, including infertile rocky soils, forests, shrubs, and even hot dry soils. Figs plants have several varieties that can be distinguished from the shape of the stem, the shape of the leaves, and the fruit's color. Figs plants are widely used as traditional medicine for both leaves and fruit. Noted in several countries have used the Figs plant as one of the plants used for traditional medicine. Figs plants are widely used for antioxidants, anticancer, hepatoprotective, antidiabetic, antibacterial, antipyretic, antituberculosis, antispasmodic antiplatelet in several countries. Figs plants contain secondary metabolites of alkaloids, latexonins, phenols, and flavonoids. There is one method of multiplication of Figs plants that began to be widely used, namely plant tissue culture. Plant tissue culture is a method of propagation using tissue slices or parts of plants that are small and in aseptic conditions. Several studies have been obtained to trace figs plants by tissue culture methods using slices of leaves and shoots.
Peningkatan Kualitas Produk Paguyuban Jamu Manunggal Kota Cimahi Melalui Standardisasi Bahan Baku Fahrauk Faramayuda; Ari Sri Windyaswari; Ridwan Ilyas; Dhimas Ariya Wibiksana; Nursafira Khairunnisa Ismail; Reyhan Adriana Deris; Rifaz Muhammad Sukma; Tzazkia Febriyana Akbar; Chandani Nurul Hafizah; Rizka Khoirunnisa Guntina
AJAD : Jurnal Pengabdian kepada Masyarakat Vol. 3 No. 2 (2023): AUGUST 2023
Publisher : Lembaga Mitra Solusi Teknologi Informasi (L-MSTI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59431/ajad.v3i2.185

Abstract

The activity of the community of herbal medicine manunggal in Cimahi city, as the main partner, is to guide the processing of traditional medicines and the herbal medicine business. The proposing team held an initial meeting and socialization for members of the Jamu Manunggal community in the city of Cimahi on December 25, 2021, regarding counseling on planting, post-harvest processing, and the benefits of the cat's whiskers plant. From the results of these activities, several problems were identified: the raw materials for traditional medicines in the Jamu Manunggal Association needed to be better standardized. This activity aims to improve the quality of traditional medicinal products through standardization. The results of the drying shrinkage testing of the five medicinal raw materials met the standards in the Indonesian Herbal Pharmacopoeia. In testing the water-soluble ash content, the levels obtained were not too large illustrating the potential for minor contamination of traditional medicinal raw materials. The general conclusion is that the raw materials for traditional medicine in the Jamu Manunggal Association of Cimahi City have good quality.
Sosialisasi Penanganan Pasca Panen Bahan Baku Rempah Obat Tradisional Fahrauk Faramayuda; Soraya Riyanti; Akhirul Kahfi Syam; Ari Sri Windyaswari; Yeni Karlina; Remare Halomoan Limbong; Anggita Esa Putri Fitrichia; Ananda Tunjung Pertiwi; Trialisa Aprilia; Ema Mutya; Renti Mutiara Dewi; Dwi Ayu Pratiwi; Usi Septiani; Esanda Zulfi Amedea; Yesi Wulandari; Adinda Fitriani; Ami Soega Dwigantina
Kawanad : Jurnal Pengabdian kepada Masyarakat Vol. 1 No. 2 (2022): October
Publisher : Yayasan Kawanad

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56347/kjpkm.v1i2.52

Abstract

Community service activities carried out by students of Universitas Jenderal Achmad Yani were carried out on August 29, 2022, taking place in a medicinal plant garden, Faculty of Pharmacy, Universitas Jenderal Achmad Yani which was attended by UMKM Spice Nusantara Bandung participants. The socialization carried out was the presentation and delivery of post-harvest processing materials (wet sorting, washing, drying, and dry sorting) and the standardization of traditional raw materials. Conventional medicine is a form of treatment efforts in the community to support health which is currently being recommended by the government. Communities can use the toga as an economical and efficient measure to maintain body immunity because the community can obtain and use the toga quickly and simply to maintain family health. The postharvest process greatly determines the existence of active compounds that are efficacious for treatment. Incorrect postharvest management can change, reduce, or destroy the active substance of a plant into a substance that has no therapeutic effect and can even endanger health. The results of the participant's level of understanding were carried out post-test with the results of what is the purpose of post-harvest processing (100%), the sequence of post-harvest processing (80%), what is the general drying temperature (100%), a medicinal plant has good quality and efficacy then we need to know (80%), and what is the function of the washing process (90%) with the conclusion that socialization activities can significantly increase the knowledge of participants from MSMEs regarding planting, post-harvest processing, and the properties of medicinal plants significantly.
KAJIAN PENDAHULUAN POTENSI ANTI KANKER DENGAN UJI TOKSISITAS METODE BRINE SHRIMP LETHALITY TEST (BSLT) TERHADAP EKSTRAK ETANOL DAN FRAKSI-FRAKSI DARI KULIT BATANG KEMIRI Aleurites moluccana (L.) Willd. Ari Sri Windyaswari; Fahrauk Faramayuda; Dessy Ratnasari
Kartika : Jurnal Ilmiah Farmasi Vol 3 No 1 (2015)
Publisher : Fakultas Farmasi Universitas Jenderal Achmad Yani, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26874/kjif.v3i1.95

Abstract

ABSTRAK Pohon kemiri Aleurites moluccana (L.) Willd.,  adalah tanaman asli Indonesia multiguna, tumbuh menyebar hingga 10-15 meter pada area terbuka di dataran Indonesia Malaysia dan kepulauan Pasifik. Penelitian sebelumnya menunjukkan tanaman kemiri mengandung tanin, saponin, flavonoida dan polifenol.  Penelitian  ini bertujuan untuk mengetahui potensi anti kanker melalui pengujian toksisitas ekstrak etanol kulit batang kemiri Aleurites moluccana (L.) Willd. dengan metode BSLT menggunakan hewan uji larva udang Artemia salina. Pengukuran toksisitas dinyatakan dengan nilai LC50. Pembuatan ekstrak dilakukan dengan teknik maserasi menggunakan pelarut etanol. Hasil pengujian toksisitas ditunjukkan dengan nilai LC50 dari ekstrak etanol, fraksi etil asetat, fraksi n-heksana, dan fraksi air.  Nilai toksisitas yang paling kuat hingga paling lemah adalah fraksi etil asetat, fraksi n-heksan, ekstrak etanol, fraksi air secara berturut-turut adalah 17,10 ppm; 35,74 ppm; 39,29 ppm; dan 378,532 ppm. Intensitas nilai LC50  hasil pengujian BSLT dari fraksi etil asetat, fraksi n-heksan, ekstrak etanol dan fraksi air berturut-turut adalah sangat toksik, sangat toksik, sangat toksik, dan toksik. Hasil Kromatografi Lapis Tipis (KLT) menggunakan penampak bercak spesifik menunjukkan dugaan golongan flavonoid pada ekstrak etanol dan fraksi etil asetat pada kulit batang kemiri. Kata kunci   :  BSLT, kulit batang kemiri, Aleurites moluccana (L.) Willd., flavonoid. ABSTRACT Aleurites moluccana (L.) Willd., also known as candlenut, is a native to Indonesia great domesticated multipurpose trees, typically grows to 10-15 m in open areas,  It is native to the Indo-Malaysia region and was introduced throughout the Pacific Island. Previous studies have demonstrated that the leaves and stem bark of Aleurites moluccana (L.) Willd. presents  tannins, saponin, flavonoid, and polyphenols. The aim of this research was to determine the toxicity value using BSLT method as screening for new potential cytotoxic drug. This research was started with maceration technique using ethanol solvent. The research was started with maceration method using ethanol solvent. Determination of toxicity value of Aleurites molucana (L.) Willd. stem bark were examined using BSLT method. The toxicity value for extract and each fractions was reported as medial lethal concentration (LC50) value, expressed in ppm. The LC50 value using BSLT method of ethyl acetate fraction, n-hexane fraction, ethanol extract, water fraction were 17,10 ppm; 35,74 ppm; 39,39 ppm; 380,93 ppm respectively. While intensity of LC50 value for toxicity value of ethyl acetate fraction, n-hexane fraction, ethanol extract, water fraction were very toxic, very toxic, very toxic, and toxic. Chromatogram pattern were observed by Thin Layer Chromatography (TLC) with specific spray agent, detected the flavonoid in ethanol extract and ethyl acetate fraction from stem bark of Aleurites moluccana (L.) Willd. Key words   : BSLT, stem bark of candlenut, Aleurites moluccana (L.) Willd., flavonoid.
Profil fitokimia selada laut (Ulva lactuca) dan mikro alga filamen (Spirogyra sp) sebagai bahan alam bahari potensial dari perairan Indonesia Ari Sri Windyaswari; Elfahmi Elfahmi; Fahrauk Faramayuda; Soraya Riyanti; Oktiyas Muzaky Luthfi; Inna Puspa Ayu; Niken Tunjung Murti Pratiwi; Khairunisa Harizqi Nurul Husna; Ridzka Magfirah
Kartika : Jurnal Ilmiah Farmasi Vol 7 No 2 (2019)
Publisher : Fakultas Farmasi Universitas Jenderal Achmad Yani, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26874/kjif.v7i2.288

Abstract

AbstrakPerairan Indonesia merupakan habitat bagi berbagai spesies makro dan mikro alga. Selada laut (Ulva lactuca) adalah salah satu makroalga hijau yang secara empiris digunakan sebagai makanan oleh masyarakat Indonesia yang hidup dipesisir pantai. Pada perairan tawar, ganggang hijau (Spirogyra porticalis) merupakan mikroalga filamen yang berperan penting sebagai bioindikator dalam sistem akuatik. Penelitian ini bertujuan untuk mengetahui profil fitokimia dari selada laut dan ganggang hijau yang tumbuh di perairan Indonesia. Hasil pengujian kualitatif pada selada laut (Ulva lactuca)  menunjukkan kandungan metabolit primer  dan sekunder berturut-turut adalah karbohidrat, alkaloid, flavonoid, mono dan seskuiterpenoid. Sementara itu ganggang hijau (Spirogyra porticalis) mengandung karbohidrat, protein, alkaloid, flavonoid, fenolik, tannin, kuinon, mono dan seskuiterpenoid. Pola kromatogram selada laut (Ulva lactuca) dan  ganggang hijau (Spirogyra porticalis) mendeteksi aktivitas antioksidan yang dimiliki oleh senyawa- metabolit sekunder  seperti fenol, tannin, flavonoid, mono dan seskuiterpenoid yang memiliki variasi kepolaran dari semi hingga polar. Hasil uji pendahuluan aktivitas antioksidan menggunakan metode dinamolisis menunjukkan selada laut (Ulva lactuca) dan  ganggang hijau (Spirogyra porticalis) memiliki aktivitas antioksidan dan berpotensi dikembangkan sebagai obat, suplemen, eksipien farmasi dan makanan nutrisi. Kata kunci: selada laut (Ulva lactuca), ganggang hijau (Spyrogyra porticalis), antioksidan, bahari, Indonesia. AbstractIndonesian waters are habitat for various macro and micro algae species. Sea lettuce Ulva lactuca is one of the green macroalgae that is empirically used as food by Indonesian people. In freshwater, green algae Spirogyra porticalis is filament microalgae that play an important role as bioindicators in the aquatic system. The aim of this research was to profiling the chemical constituent from native Indonesian sources, Ulva lactuca  and Spirogyra porticalis. The results of  Ulva lactuca  qualitative analysis showed the content of primary and secondary metabolites are carbohydrates, alkaloids, flavonoids, mono, and sesquiterpenoids, respectively. On the other hand, green algae Spirogyra porticalis carbohydrates, proteins, alkaloids, flavonoids, phenolics, tannins, quinones, mono, and sesquiterpenoids, respectively. The chromatogram pattern of sea lettuce Ulva lactuca and  Spirogyra porticalis showed the antioxidant activity caused by secondary metabolites such as phenol, tannin, flavonoids, mono and sesquiterpenoids which were various polarity. Preliminary test results of antioxidant activity with the dinamolysis method showed sea lettuce Ulva lactuca  and and green algae Spirogyra porticalis have antioxidant activity. It potentially developed as drugs, supplements, pharmaceutical excipients and nutritional foods. Keywords: sea lettuce Ulva lactuca, green microalgae Spyrogyra porticalis, antioxidant, marine, Indonesia,
EFFECT OF EXTRACTION METHOD ON ANTIOXIDANT ACTIVITY OF PALM PALM LEAVES (Elaeis guineensis Jacq.) Fahrauk Faramayuda; Ari Sri Windyaswari; Yeni Karlina; Muhamad Raihan Maulana; Rizka Khoirunnisa Guntina
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 9 No 1 (2024)
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v9i1.994

Abstract

Oil palm (Elaeis guineensis Jacq.) is a plant that is native to Africa and South America. This plant can grow well in tropical areas, such as Indonesia. Indonesia is currently one of the largest producers of palm oil worldwide. As the area of palm oil plantations increases, the potential for waste from this plant continues to increase. The potential for palm oil leaf waste production in Indonesia is 658 kg dry matter/hectare/year. Palm oil leaf waste has been widely processed into organic fertilizers and animal feeds. This plant has the potential to be developed into a source of traditional medicinal ingredients. Based on the abundant sources of palm oil leaves and their pharmacological potential, palm oil leaves can be used as a source of raw materials for traditional medicine. This study aimed to compare the antioxidant activities of oil palm leaf extracts obtained by maceration and reflux to determine which extraction method produces the best antioxidant activity. Extraction was carried out using 70% ethanol solvent by maceration and reflux. The results of the phytochemical screening showed that oil palm leaves contain flavonoids, polyphenols, saponins, quinones, steroid-triterpenoids, and monoterpene-sesquiterpenes. Antioxidant activity using a UV-Visible spectrophotometer with DPPH free radicals showed that the extract obtained by maceration and reflux methods had IC50 values of 46.61 ± 1.76 ug/mL and 55.21 ± 2.91 ug/mL respectively. Therefore, extraction by maceration produces a better antioxidant activity.  Keywords: Palm leaves; Traditional medicine; Extraction; Active compound stability; Antioxidant
POTENSI SALEP EKSTRAK ETIL ASETAT Jatropha multifida L. SEBAGAI AGEN PENYEMBUHAN LUKA Syam, Akhirul Kahfi; Lahagu, Helga Nitulo Berliana; Ramdhani, Amalia Kusuma; Azhar, Farah Salsabilla Saidah; Mardiana, Grace Selly; Dewilestari, Meyra Pratami; Windyaswari, Ari Sri
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 9 No 1 (2024): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jiis.v9i1.1630

Abstract

Jarak tintir (Jatropha multifida L.) umumnya terkenal sebagai tanaman hias yang berasal dari suku Euphorbiaceae. Masyarakat secara empiris memanfaatkan bagian getahnya sebagai obat luka. Telah dilakukan penelitian mengenai suku Euphorbiaceae memiliki aktivitas sebagai antioksidan pada ekstrak etil asetat dengan nilai IC50 < 50 ug/mL. Tujuan penelitian  ini untuk melihat  potensi metabolit sekunder pada ekstrak etil asetat yang berpotensi sebagai antioksidan untuk dikembangkan sebagai kosmedika penyembuhan luka.  Ekstraksi simplisia batang jarak tintir dilakukan menggunakan Refluks dengan pelarut etil asetat. Aktivitas antioksidan yang dinyatakan dalam nilai IC50 diuji menggunakan metode peredaman radikal bebas DPPH. Formulasi sediaan salep menggunakan basis vaselin album dan ekstrak etil asetat dengan konsentrasi 5,5% dan 11%. Potensi aktivitas penyembuhan luka dari ekstrak etil asetat dilakukan dengan metode telaah jurnal. Hasil uji aktivitas antioksidan ekstrak etil asetat memberikan nilai IC50 110,4 µg/mL. Formulasi sediaan salep ekstrak etil asetat batang Jarak tintir dengan konsentrasi 5,5% dan 11% memenuhi persyaratan uji evaluasi sediaan salep yang baik. Hasil telaah pustaka, metabolit sekunder yang memiliki potensi aktivitas antioksidan juga memiliki potensi sebagai agen penyembuhan luka dengan berbagai mekanisme penyembuhan dan metabolit sekunder yang bertanggung jawab sebagai agen penyembuhan luka antara lain alkaloid, flavonoid, tanin dan saponin.
Penyuluhan Manfaat Tanaman Obat Tradisional dan Pengelolaan Website Paguyuban Jamu Manunggal Kota Cimahi Faramayuda, Fahrauk; Ilyas, Ridwan; Paramita, Veronika Santi; Windyaswari, Ari Sri; Ismail, Nursafira Khairunnisa; Akbar, Tzazkia Febriyana; Putri, Dhiffa Namira Alifia; Adriana, Reyhan
AJAD : Jurnal Pengabdian kepada Masyarakat Vol. 4 No. 3 (2024): DECEMBER 2024
Publisher : Divisi Riset, Lembaga Mitra Solusi Teknologi Informasi (L-MSTI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59431/ajad.v4i3.378

Abstract

Paguyuban Jamu Manunggal Cimahi is located at Gang M. Ardjo No.224. Based on the initial survey, the problem was identified that knowledge about the benefits of traditional medicinal plants was still limited. In addition, the sales of products are still ineffective because the marketing is still carried out conventionally. This underlies the need for counseling on the benefits of traditional medicinal plants and website management at Paguyuban Jamu Manunggal which aims to increase the knowledge of the participants and to expand the target market. The counseling activity was carried out on October 08, 2023 which began with a pre-test, presentation, post-test, and workshop. Based on the test results, it can be concluded that the counseling activities can significantly increase the knowledge of the participants, this is indicated by the average value of the pre-test and post-test which was originally 60 to 95.3.
Co-Authors Adinda Fitriani Adriana, Reyhan Akbar, Tzazkia Febriyana Akhirul Kahfi Syam Amedea, Esanda Zulfi Ami Soega Dwigantina Ananda Tunjung Pertiwi Andrian Rafliana Supriatnaputra Anggita Esa Putri Fitrichia Anna Choirunnisa, Anna Aprilia, Trialisa Ayu, Inna Puspa Azhar, Farah Salsabilla Saidah Chandani Nurul Hafizah dessy ratnasari Dessy Ratnasari Dewi, Renti Mutiara Dewilestari, Meyra Pratami Dhimas Ariya Wibiksana Dwi Ayu Pratiwi Dwigantina, Ami Soega Elfahmi Elfahmi, Elfahmi Ema Mutya Esanda Zulfi Amedea Fahrauk Faramayuda Fahrauk Faramayuda Fahrauk Faramayuda Fahrauk Faramayuda Fahrauk Faramayuda, Fahrauk Faizal Hermanto Febrinella, Catellya Fifi Gus Dwiyanti Fitriani, Adinda Fitrichia, Anggita Esa Putri Guntur Berlian Inna Puspa Ayu Ismail, Nursafira Khairunnisa Julia Ratnawati Julia Ratnawati Julia Ratnawati, Julia Khairunisa Harizqi Nurul Husna Lahagu, Helga Nitulo Berliana Limbong, Remare Halomoan Luthfi Fauziah Majariana Krisanti Mardiana, Grace Selly Maria Tri Miarsih Muhamad Raihan Maulana Mutya, Ema Niken Tunjung Murti Pratiwi Niken Tunjung Murti Pratiwi Nurhayati, Viola Aditya Nursafira Khairunnisa Ismail Nurul Safirah Safrudin Oktiyas Muzaky Luthfi Paramita, Veronika Santi Pertiwi, Ananda Tunjung Pratiwi, Dwi Ayu Purwoko, Agus Putri, Dhiffa Namira Alifia Ramdhani, Amalia Kusuma Remare Halomoan Limbong Renti Mutiara Dewi Reyhan Adriana Deris Ridwan Ilyas Ridzka Magfirah Rifaz Muhammad Sukma RIZKA KHOIRUNNISA GUNTINA, RIZKA KHOIRUNNISA Salsa Rizqyana Billa Septiani, Usi Sigid Pamungkas Wicaksono Soraya Riyanti Soraya Riyanti Soraya Riyanti, Soraya Suci Nar Vikasari, Suci Nar SURYANI Trialisa Aprilia Tzazkia Febriyana Akbar Usi Septiani Viola Aditya Nurhayati Wulandari, Yesi Yeni Karlina Yeni Karlina Yeni Karlina, Yeni Yesi Wulandari