Effectiveness of Giving Crude Extract of Red Betel Leaf (Piper crocatum) on the Hematology and Histopathology Profile of Goldfish (Cyprinus carpio) Gills Infected with Aeromonas hydrophila Bacteria

Pratama, Muhammad Jusril Arief
Fadjar, Mohammad
Paricahya, Akhsan Fikrillah

Jurnal Penelitian Pendidikan IPA (JPPIPA)
Vol 10 No 12 (2024): December

The purpose of this study was to analyze the hematology and histopathology of the gills of carp (C. carpio) treated with active compounds of red betel leaf extract (P. crocatum). This research method used a completely randomized design (CRD). The treatments used in this study were doses of 75 mg/L, 150 mg/L, 225 mg/L, 300 mg/L, 375 mg/L, negative control (healthy fish), and positive control (positive control), (healthy fish), and positive control (chloramphenicol antibiotic). Results of hematology and histopathology studies the results of hematology and histopathology studies on the gills of carp (C. carpio) after being infected with A. hydropilla bacteria experienced stress, this can be seen from. decreased red blood cells, increased leukocytes, and damage to the gill tissue. Carp returned to normal after being treated with red betel leaf extract. The best dose obtained after treatment was a dose of 300 mg/L. The results of clinical symptom observations showed a change from abnormal to normal conditions in goldfish after being treated. The conclusion is that red betel leaf extract contains dominant compounds in the form of flavonoids and alkaloids which can be useful as a medicine for goldfish infected with A. hydropilla bacteria.