Jurnal Farmasi Medica (Pharmacy Medical Journal) PMJ
Vol. 7 No. 2 (2024): Jurnal Farmasi Medica/Pharmacy Medical Journal

PENGARUH KONSENTRASI GLUKOMANAN TERHADAP SIFAT FISIK SEDIAAN GEL ASAM ASKORBAT

Abdullah, Surya Sumantri (Unknown)
Antasionasti, Irma (Unknown)
Rundengan, Gerald Edward (Unknown)
Tasiam, Ezrani (Unknown)
Abdullah, Rezky Putri Indarwati (Unknown)



Article Info

Publish Date
28 Jan 2025

Abstract

Gel preparations usually contain gelling agents which are critical factors that can affect the physical properties of the gel. The purpose to determine the appropriate variation of glucomannan concentration in the formulation of ascorbic acid gel on the physical characteristics of the gel. The research method began with the formulation of gel preparations using glucomannan as a gelling agent with variations in glucomannan concentrations at F1 (1%), F2 (1.5%) and F3 (2%). The gels were evaluated by their physical properties, including in the organoleptic, pH, homogeneity, adhesion, and spreadability tests. The research showed that in the pH and adhesiveness tests, increasing the concentration of glucomannan could increased the pH and adhesiveness of the gel. However, the spreadability of the gel decreased with increasing glucomannan concentration. The gel formula with 2% glucomannan concentration (F3) showed higher adhesion, as well as higher pH, although the gel spreadability decreased. From the evaluation results, all meet requirement for physically stable.

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Journal Info

Abbrev

pmj

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Medicine & Pharmacology Public Health

Description

Jurnal Farmasi Medika merupakan jurnal yang diterbitkan oleh PS. Farmasi FMIPA Universitas Sam Ratulangi dengan frekuensi terbit 2 kali dalam setahun di bulan Juni dan Desember. Tujuan pernebitan jurnal ini adalah untuk memberikan sarana bagi para akademisi, peneliti maupun praktisi untuk ...