Obat: Jurnal Riset Ilmu Farmasi dan Kesehatan
Vol. 3 No. 1 (2025): January: OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan

Penetapan Kadar Kalsium Laktat dengan Menggunakan Metode Titrasi Kompleksometri

Nur Khadijah Anasyah (Universitas Muhammadiyah Makassar, Sulawesi Selatan)
Nurfadillah Nurfadillah (Universitas Muhammadiyah Makassar, Sulawesi Selatan)
Dian Fadillah (Universitas Muhammadiyah Makassar, Sulawesi Selatan)
Rini Ariyanti (Universitas Muhammadiyah Makassar, Sulawesi Selatan)
Musfirah Musfirah (Universitas Muhammadiyah Makassar, Sulawesi Selatan)
Putri Indah Ramadhani (Universitas Muhammadiyah Makassar, Sulawesi Selatan)
Amri Alwi (Universitas Muhammadiyah Makassar, Sulawesi Selatan)
Yuniarsyah Yuniarsyah (Universitas Muhammadiyah Makassar, Sulawesi Selatan)
Rismawati Kalean (Universitas Muhammadiyah Makassar, Sulawesi Selatan)
Sulfiana Sulfiana (Universitas Muhammadiyah Makassar, Sulawesi Selatan)
Yuyun Sri Wahyuni (Universitas Muhammadiyah Makassar, Sulawesi Selatan)
Masyhuri Muhaimin (Universitas Muhammadiyah Makassar, Sulawesi Selatan)
Haryanto Haryanto (Universitas Muhammadiyah Makassar, Sulawesi Selatan)



Article Info

Publish Date
17 Jan 2025

Abstract

This research aims to determine calcium lactate levels using the complexometric titration method, which involves the formation of a complex between metal ions and ligands, specifically using EDTA (Ethylenediaminetetraacetate) as a titrant. The sample was dissolved in distilled water, the murexide indicator was added, and titrated with complexon III solution until the color changed from orange to violet as a marker for the end point of the titration. Data analysis shows that the percentage of calcium lactate levels in replication (1) is 93.32%, replication (2) 101.60%, replication (3) 95.93%, replication (4) 103.78%, replication (5) 109.02%, replication (6) 87.87%, replication (7) 95.93% and replication (8) 100.95%, and the percentage obtained the average purity is 98.55%. However, replications 5 and 6 did not comply with the standards of the Indonesian Pharmacopoeia VI edition (94.0–106.0%). This research shows that the complexometric titration method is effective in determining calcium lactate levels with good accuracy, as long as it is carried out with appropriate procedures and strict control of the analysis conditions.

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Journal Info

Abbrev

OBAT

Publisher

Subject

Health Professions Nursing Public Health

Description

Organisasi Farmasi, Kedokteran, Kimia Organik Sintetis, Kimia Alam, Biokimia, Analisis Kimia, Kimia Fisika, Biologi, Mikrobiologi, Jaringan Budaya, Botani dan Hewan terkait Produk Farmasi, Keperawatan, Kebidanan, Analis Kesehatan, Gizi dan Kesehatan ...