Aptisi Transactions on Technopreneurship (ATT)
Vol 7 No 1 (2025): March

Gold Nanoparticle Synthesis Using Quercetin: Innovation in Biopreneur

Pertiwi, Ratih Dyah (Unknown)
Fitria, Pika Ayu (Unknown)
Utami, Tyas Putri (Unknown)
Pamungkas, Rian Adi (Unknown)
Pradana, Reinaldo (Unknown)
Chamroonsawasdi, Kanittha (Unknown)



Article Info

Publish Date
11 Mar 2025

Abstract

Biosynthesis offers an environmentally friendly approach for manufacturing nanoparticles, with flavonoids such as quercetin showing potential as reducing agents. This study aimed to synthesize gold nanoparticles (AuNPs) from HAuCl4 using quercetin as a reducing agent. The synthesis process was monitored using UV-Vis spectrophotometry, and the particle size and stability of the nanoparticles were characterized using a Particle Size Analyzer (PSA). The synthesized AuNPs exhibited a color change from light yellow to deep purple, with a peak absorbance between 500 600 nm. The average particle size was found to be 116.7 nm, with a zeta potential of -12.2 mV, and a polydispersity index of 0.293. The inhibitory activity of the AuNPs was assessed by their effect on the tyrosinase enzyme, yielding an IC50 value of 970 μg/mL. These results suggest that gold nanoparticles synthesized using quercetin are stable and exhibit potential inhibitory activity against tyrosinase. The study concludes that this green synthesis method has the potential for further development in drug delivery systems, providing an innovative approach in biopreneurship.

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Journal Info

Abbrev

att

Publisher

Subject

Humanities Computer Science & IT Economics, Econometrics & Finance Education Social Sciences

Description

APTISI Transactions on Technopreneurship (ATT) is an international triannual open access scientific journal published by  Pandawan Sejahtera Indonesia. ATT publishes original scientific researchers from scholars and experts around the world with novelty based on the theoretical, experimental, ...