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Predictive Factors of Diabetes Mellitus Self-Management (DMSM) Practice: A Systematic Review and Meta-Analysis Pamungkas, Rian Adi; Usman, Andi Mayasari; Chamroonsawasdi, Kanittha; Sari, Widia
Jurnal Keperawatan Soedirman Vol 19 No 1 (2024): Jurnal Keperawatan Soedirman (JKS)
Publisher : Fakultas Ilmu-ilmu Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.jks.2024.19.1.9899

Abstract

The diabetes mellitus self-management (DMSM) is integral to controlling blood glucose and preventing diabetes complications. There were still gaps in the analysis controversy of the outcome that need to be explored by systematic review and meta-analysis. The review aimed to synthesize the predictive factors associated with practice DMSM practice among Type 2 Diabetes Mellitus (T2DM). This study applied the systematic and meta-analysis method. Three databases, Scopus, PubMed, and Medline, were included in this study to obtain the relevant articles. Keywords used were “self-management”; “diabetes mellitus”; self-care; factors associated with self-management". Comprehensive Meta-Analysis (CMA) was used to analyze and interpret the effect size of the review study. The results showed that 15 predictive factors were associated with DMSM practice, including age, sex, education level, illness duration, and financial barriers. Diabetes knowledge, insulin in treatment, belief of treatment, social support, occupational, personality, diabetes-specific emotional distress, perception of the disease, quality interaction with healthcare providers, and self-efficacy were considered predictive factors. The findings suggested that a wide range of personal and environmental factors were the most influential factors associated with the implementation of DMSM in health care services. Therefore, it is vital to construct theory-based strategies to improve DMSM practice among diabetes population.
Gold Nanoparticle Synthesis Using Quercetin: Innovation in Biopreneur Pertiwi, Ratih Dyah; Fitria, Pika Ayu; Utami, Tyas Putri; Pamungkas, Rian Adi; Pradana, Reinaldo; Chamroonsawasdi, Kanittha
Aptisi Transactions On Technopreneurship (ATT) Vol 7 No 1 (2025): March
Publisher : Pandawan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34306/att.v7i1.405

Abstract

Biosynthesis offers an environmentally friendly approach for manufacturing nanoparticles, with flavonoids such as quercetin showing potential as reducing agents. This study aimed to synthesize gold nanoparticles (AuNPs) from HAuCl4 using quercetin as a reducing agent. The synthesis process was monitored using UV-Vis spectrophotometry, and the particle size and stability of the nanoparticles were characterized using a Particle Size Analyzer (PSA). The synthesized AuNPs exhibited a color change from light yellow to deep purple, with a peak absorbance between 500 600 nm. The average particle size was found to be 116.7 nm, with a zeta potential of -12.2 mV, and a polydispersity index of 0.293. The inhibitory activity of the AuNPs was assessed by their effect on the tyrosinase enzyme, yielding an IC50 value of 970 μg/mL. These results suggest that gold nanoparticles synthesized using quercetin are stable and exhibit potential inhibitory activity against tyrosinase. The study concludes that this green synthesis method has the potential for further development in drug delivery systems, providing an innovative approach in biopreneurship.
A Mixed-Methods Evaluation of the Feasibility of a Health Coaching Program to Improve Neuropathy Screening Practices and Prevent Foot Ulcers in Diabetic Patients at Risk of Complications Pamungkas, Rian Adi; Chamroonsawasdi, Kanittha; Usman, Andi Mayasari
Jurnal Keperawatan Soedirman Vol 20 No 1 (2025): Jurnal Keperawatan Soedirman (JKS)
Publisher : Fakultas Ilmu-ilmu Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.jks.2025.20.1.12947

Abstract

Neuropathy was crucial to develop foot ulcer complication. The study aimed to understand the needs and barriers to program implementation, assess feasibility, and examine the effects of diabetes health coaching programs on outcomes. This pilot study applied a sequential exploratory mixed-methods design that consisted of a quasi-Intervention design, pre-test, and post-test in the first phase, followed by a qualitative study in the second phase. Content analysis was applied to describe the qualitative findings. A paired t-test and independent t-test to measure mean differences within and between groups. The intervention group participated in a 12-week health coaching program including problem-solving coaching, narrative-based coaching, mindfulness coaching, skill coaching, and self-reporting. The keys findings were: 1) bridging the mind and body for consistency; 2) a heightened perception of susceptibility; 3) timing for being mindfulness; 4) inadequate knowledge and skills on diabetes complication; 5) a sense of embracement regarding diabetes complications. The quantitative study confirmed that patients who participated in the program showed significant improvements in knowledge, neuropathy screening, and foot ulcer prevention. Additionally, the program led to better clinical outcomes in preventing diabetic foot ulcer compared the control group. A health coaching program was feasible for implementation in the community health center.
Clinical Features of Peripheral Neurophaty among Onset Type 2 Diabestes Mellitus: A Michigan Neuropathy Screening Instrument (MNSI) Approach Pamungkas, Rian Adi; Usman, Andi Mayasari; Chamroonsawasdi, Kanittha
Indonesian Contemporary Nursing Journal (ICON Journal) Vol. 7 No. 2 (2023): Volume 7 No. 2 Februari 2023
Publisher : Faculty of Nursing, Universitas Hasanuddin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20956/icon.v7i2.21689

Abstract

Aims: Neuropathy is one of the complications that can occur in patients with Type 2 Diabetes Mellitus, around 21.3% to 34.5%. Untreated neuropathy can lead to diabetic foot ulcers that can lead to amputation. This can be prevented by conducting early detection using a neuropathy screening instrument. The study aimed to identify neuropathy symptoms through early examination of patients with type 2 diabetes using the Michigan Neuropathy Screening Instrument (MNSI). Method: The descriptive study with a survey was approached in this study.  One hundred respondents with type 2 diabetes mellitus were selected using the purposive sampling technique.   Results: The results showed that out of 100 patients had clinical symptoms of sensory neuropathy, such as pain and sensitivity disorders in the soles of the feet.  In addition, autonomic neuropathy is in the form of cramps in the leg muscles.  The level of neuropathy showed that from 100 patients, there were 59 respondents with low risk of neuropathy, 40 respondents with moderate risk, and 1 respondent with severe risk.   Conclusion: Patients with Diabetes, primarily Type 2, have various neuropathy symptoms such as impaired nerve function: numbness, burning, and hypersensitivity, which can lead to diabetic foot ulcers.  Therefore, early detection of neuropathy prevention is essential.