Journal of Innovative and Creativity
Vol. 5 No. 2 (2025)

Peran Kimia Medisinal Dalam Pengembangan Obat Antibakteri: Pendekatan Komputasi dan Eksplorasi Senyawa Bioaktif dari Sumber Alam

Saeful Amin (Universitas Bakti Tunas Husada)
AlifiaFauziah (Universitas Bakti Tunas Husada)
Najelina Shifa (Universitas Bakti Tunas Husada)
Neneng Reva (Universitas Bakti Tunas Husada)



Article Info

Publish Date
27 Apr 2025

Abstract

The development of bacterial resistance to conventional antibiotics is a serious challenge in the world of health, so innovative approaches are needed in the discovery of new antibacterial drugs. Medicinal chemistry plays a vital role in this process through interdisciplinary strategies that combine molecular design, computational technology, and natural resource exploration. Computational approaches such as molecular docking and deep learning allow efficient compound screening, accelerating the process of identifying potential drug candidates. On the other hand, natural resources provide a variety of bioactive compounds such as alkaloids, flavonoids, and terpenoids that have antibacterial activity. Case studies of the discovery of Halicin and mangiferin compounds emphasise the great potential of this method. Although challenges such as bioavailability and toxicity still exist, technological advances and the integration of computational approaches with ethnopharmaceuticals open up great opportunities in the development of new, more effective and selective antibacterial agents.

Copyrights © 2025






Journal Info

Abbrev

joecy

Publisher

Subject

Education Languange, Linguistic, Communication & Media Mathematics Social Sciences Other

Description

Journal of Innovative and Creatifity (JOECY) publishes research articles in the field of education which report empirical research on topics that are significant across educational contexts, in terms of design and findings. The topic could be in curriculum, teaching learning, evaluation, quality ...