This study aims to analyze the effect of the Project Based Learning model integrated with the Merdeka Curriculum on the learning outcomes of Grade X students in Biotechnology material at SMK Islam Al-Azhar Jember. The study employed a quasi-experimental approach with a pretest-posttest non-equivalent control group design. The sample consisted of 34 students who were given pretests and posttests to measure their biotechnology learning outcomes, using a learning outcome test as the instrument. The results showed a significant improvement in students’ learning outcomes after the implementation of the Project Based Learning model integrated with the Merdeka Curriculum, with the experimental group achieving a posttest average score of 89.73, compared to 76.21 in the control group. The N-Gain score for the experimental group reached 0.73 (73%), which is categorized as high, while the control group scored 0.56 (56%). A t-test indicated a significant difference between the two groups (p = 0.000 < 0.05). These findings indicate that the Project Based Learning model integrated with the Merdeka Curriculum is proven to be effective in improving Biotechnology learning outcomes.
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