Indonesian Journal of Pure and Applied Chemistry
Vol 8, No 1 (2025)

MOLECULAR DOCKING AND ADME STUDIES OF STIGMASTEROL COMPOUNDS AS ANTI-BREAST CANCER

Amir, Nur Insani (Unknown)
Nurfadillah, Arafah (Unknown)
Miladiarsi, Miladiarsi (Unknown)
Irma, Ade (Unknown)
Wahdaniar, Wahdaniar (Unknown)

Article Info

Publish Date
26 Aug 2025

Abstract

Molecular docking studies of stigmasterol (test ligand) and estradiol (control ligand) against the ER-α receptor were performed using PyRx software. This study aims to determine the interaction between stigmasterol ligands and ER-α receptors by the molecular docking method using PyRx. The study results show that stigmasterol and estradiol have the same binding energy value of -7.3 kcal/mol. The stigmasterol compound could therefore be used as a candidate for breast cancer drugs.

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Journal Info
Indonesian Journal of Pure and Applied Chemistry
Website

Abbrev

IJoPAC

Publisher

Universitas Tanjungpura

Subject

Biochemistry, Genetics & Molecular Biology Chemistry

Description

Indonesian Journal of Pure and Applied Chemistry (IJoPAC) was first established in 2018 as a scientific journal that accommodates researchers and education practitioners to publish scientific work and research results which are the results of experiments or literature studies in the field of ...