ZnO has been produced using a green synthesis method. This research aims to determine the effect of NaOH variations on ZnO nanoparticles obtained using red betel leaf extract. The variation of NaOH used is 0,2; 0,4; 0,6; the characterization carried out was Fourier Transformation Infra Red (FTIR), X-Ray Difraction (XRD), Scanning Electron Microscopy (SEM), dan Ultra Violet Vissible (UV DRS) the results of FTIR characterization show that the functional groups in red betel leaves play a role in the information of ZnO nanoparticles, XRD characrerization shows diffraction peaks of ZnO nanoparticles and the presence of NaNO3 phase at 0,2; 0,4; 0,6; and 1 M variation. Then, the SEM results showed a spherical morphology at a 1 M variation, and the UV-DRS results showed an absorption peak at 331 nm and a band gap energy of 3.11 eV.
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