<![CDATA[Hypertension is a chronic disease that requires long-term management. The use of medicinal plants as complementary therapy is increasingly recognized, although scientific evidence remains limited. This study aimed to evaluate the effectiveness of amlodipine with concomitant herbal therapy (bay leaves, celery, and/or cucumber) compared with amlodipine monotherapy in hypertensive patients. A retrospective cohort design was employed using medical record data and patient questionnaires from three community health centers in Surakarta. Treatment effectiveness was measured by the achievement of the target blood pressure over three months. Data were analyzed using bivariate tests and multivariate logistic regression. The results showed that clinical effectiveness was higher in the amlodipine group with concomitant herbal therapy (bay leaves, celery, and/or cucumber) at 78.4% compared to amlodipine monotherapy at 68.8%, although the difference was not statistically significant (p=0.160). Factors significantly associated with treatment effectiveness were medication adherence (p<0.001), baseline systolic blood pressure (p<0,001), and educational level (p=0,047). Concomitant herbal therapy with amlodipine showed potential blood pressure–lowering effects, though not statistically significant. Prospective studies or clinical trials are warranted to further assess the benefits and safety of this therapeutic approach.]]>
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