Cermin Dunia Kedokteran
Vol 51 No 7 (2024): Kedokteran Umum

Sindrom Chorea Hiperglikemia Ganglia Basalis: Laporan Kasus

Puspita, Amelia (Unknown)
Sumada, I Ketut (Unknown)
Wiratni, Ni Ketut Candra (Unknown)
Yuliani, Desie (Unknown)
Jayanthi, Ni Made Kurnia Dwi (Unknown)



Article Info

Publish Date
01 Jul 2024

Abstract

Background: Chorea hyperglycemia basal ganglia (C-H-BG) syndrome is an uncommon manifestation of diabetes mellitus seen in patients with poor glycemic control. Case: A 74-year-old poorly controlled diabetic women with acute onset of movement disorder in the form of uncontrolled choreiform movements of her left upper and lower extremity. Her initial glucose level was 289 mg/dL and HbA1C was 9.5%. Discussion: Most C-H-BG patients are older Asian female. Female predisposition is probably related to the estrogen decline during menopause, resulting in gamma-aminobutyric acid (GABA) depletion or dopamine receptors hypersensitivity and enhancement of dopaminergic system. Its pathophysiology has not been entirely defined. Conclusion: C-H-BG is a rare manifestation of poorly controlled diabetes. Early recognition and treatment of elevated blood glucose levels appear to lead to total resolution.

Copyrights © 2024






Journal Info

Abbrev

cdk

Publisher

Subject

Health Professions

Description

Cermin Dunia Kedokteran (CDK) is a Medical Journal published since 1974 and affiliated with PT Kalbe Farma Tbk. CDK is intended to help accommodate scientific publications and help increase and disseminate knowledge related to the development of medical science, pharmacy, and public health. CDK ...