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All Journal Jurnal Biomedika dan Kesehatan Cermin Dunia Kedokteran
Yuliani, Desie
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Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Stroke Iskemik pada Pasien Hemodialisis : Laporan Kasus Thiodorus, Fira; Mayung, Claraiva; Yuliani, Desie
Jurnal Biomedika dan Kesehatan Vol 6 No 1 (2023)
Publisher : Fakultas Kedokteran Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/JBiomedKes.2023.v6.119-126

Abstract

Stroke and chronic kidney disease are major health problems worldwide. Acute ischemic stroke is a significant complication in patients with end-stage renal disease undergoing hemodialysis. The incidence of stroke is about 8-10 times higher in chronic renal failure patients on hemodialysis compared to the general population. The annual incidence rate of acute ischemic stroke is reported to be about 4% in chronic renal failure patients on hemodialysis. Initiation of dialysis in chronic renal failure patients is associated with an increased risk of stroke. Chronic renal failure disease is an independent risk factor for stroke. A 57-year-old woman complained of left-side weakness during hemodialysis. Paresis of cranial nerve VII and XII and grade 3 flaccid hemiparesis sinistra were found. Electrocardiogram showed normal atrial fibrillation response. Non-contrast head CT scan showed subacute ischemic cerebral infarction in the right internal capsule. Factors that cause stroke in chronic renal failure are endothelial dysfunction, accelerated arteriosclerosis, and impaired cerebral autoregulation.
Sindrom Chorea Hiperglikemia Ganglia Basalis: Laporan Kasus Puspita, Amelia; Sumada, I Ketut; Wiratni, Ni Ketut Candra; Yuliani, Desie; Jayanthi, Ni Made Kurnia Dwi
Cermin Dunia Kedokteran Vol 51 No 7 (2024): Kedokteran Umum
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v51i7.963

Abstract

Background: Chorea hyperglycemia basal ganglia (C-H-BG) syndrome is an uncommon manifestation of diabetes mellitus seen in patients with poor glycemic control. Case: A 74-year-old poorly controlled diabetic women with acute onset of movement disorder in the form of uncontrolled choreiform movements of her left upper and lower extremity. Her initial glucose level was 289 mg/dL and HbA1C was 9.5%. Discussion: Most C-H-BG patients are older Asian female. Female predisposition is probably related to the estrogen decline during menopause, resulting in gamma-aminobutyric acid (GABA) depletion or dopamine receptors hypersensitivity and enhancement of dopaminergic system. Its pathophysiology has not been entirely defined. Conclusion: C-H-BG is a rare manifestation of poorly controlled diabetes. Early recognition and treatment of elevated blood glucose levels appear to lead to total resolution.
Co-Authors I Ketut Sumada, I Ketut Jayanthi, Ni Made Kurnia Dwi Mayung, Claraiva Pikatan, Orlando Puspita, Amelia Thiodorus, Fira Wiratmi, Ni Ketut Candra Wiratni, Ni Ketut Candra