This study presents a comparative study of hyperparameter optimization methods applied to the Light Gradient Boosting Machine (LightGBM) algorithm for asthma prediction. Traditional machine learning models often face limitations in accuracy and generalization capabilities due to suboptimal hyperparameter configurations. To address these challenges, this study evaluates and compares four approaches: Default LightGBM, RandomizedSearchCV, Optuna Optimization, and Bayesian Optimization. Experimental results show that Bayesian Optimization provides the best performance with an accuracy of 78%, a precision of 0.7778, a recall of 0.7778, an F1-score of 0.7778, and an ROC-AUC of 0.975. These findings emphasize the importance of selecting an appropriate optimization strategy to improve model performance in clinical prediction tasks. Overall, this study confirms the effectiveness of Bayesian Optimization in improving the predictive capabilities of LightGBM and provides an important contribution to the development of decision support systems in healthcare, particularly in the diagnosis and management of asthma
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