CRJIM (Clinical and Research Journal in Internal Medicine)
Vol. 6 No. 2 (2025): Volume 6 No 2, November 2025

Comparison of Carotid Intima-Media Thickness (CIMT) and Calcium-Phosphorus (Ca × P) Product Between Hemodialysis (HD) Patients and Continuous Ambulatory Peritoneal Dialysis (CAPD) Patients.

Rosandy, Kharisma Ogit (Unknown)
Winoto, Eden Suryoiman (Unknown)
Samsu, Nur (Unknown)



Article Info

Publish Date
25 Nov 2025

Abstract

Background: Cardiovascular disease is the leading cause of death in end-stage renal disease (ESRD). Carotid intima-media thickness (CIMT) and the calcium–phosphate (Ca × P) product are recognised surrogate markers of cardiovascular risk in dialysis recipients. Objective: This study aims to compare CIMT and Ca × P product levels between patients undergoing HD and CAPD. Methods: A cross-sectional study was conducted on 93 dialysis patients (49 HD, 44 CAPD) at Saiful Anwar General Hospital, Indonesia. Participants were over 18 years old, on dialysis for at least three months (HD at least twice weekly), and physically independent. Critically ill and pregnant patients were excluded. The Mann-Whitney U test compared CIMT and Ca × P levels, and Spearman's rank correlation analyzed the relationship between CIMT and Ca × P product Results: Significant differences in CIMT (p=0.0013) and Ca × P product (p<0.0001) were found between the HD and CAPD groups. A positive correlation between CIMT and Ca × P product was observed in HD patients compared to CAPD patients (r = 0.212, p = 0.044), Conclusion: This study revealed that CIMT was higher in HD patients compared to CAPD patients. Furthermore, the Ca × P product was lower in the CAPD group than in the HD group, and a positive correlation existed between CIMT and Ca × P in HD patients.

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Journal Info

Abbrev

crjim

Publisher

Subject

Education Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Other

Description

Clinical and Research Journal in Internal Medicine is the official open access journal of Internal Medicine Research Center, Department of Internal Medicine, Faculty of Medicine, Universitas Brawijaya, Malang, Indonesia. It publishes articles two times per year. It is a peer reviewed publication of ...