Jurnal Respirologi Indonesia
Vol 46 No 1 (2026)

The Effectiveness Comparison of Salmeterol/Fluticasone Propionate and Formoterol Fumarate/Budesonide on Level of Asthma Control in Moderate Persistent Asthma

Resti, Riska (Unknown)
Tarigan, Amira Permatasari (Unknown)
Pradana, Andika (Unknown)
Wahyuni, Arlinda Sari (Unknown)



Article Info

Publish Date
31 Jan 2026

Abstract

Background: Asthma is a prevalent chronic respiratory disease, affecting approximately 1–18% of the population worldwide. Despite its high prevalence, a substantial proportion of patients have partially controlled asthma, and limited data on the level of asthma control remain a significant concern. This study aimed to compare the effectiveness of salmeterol/fluticasone propionate and formoterol fumarate/budesonide in achieving asthma control levels according to the ACQ-GINA criteria. Methods: A retrospective cohort study was conducted using 61 medical records from January 2017 to December 2019. Patients with moderate persistent asthma received either salmeterol/fluticasone propionate or formoterol fumarate/budesonide for at least three months. Statistical analysis was performed using Fisher’s exact test. Results: A total of 61 patients were included. Most patients had partially controlled asthma (70.5%), followed by well-controlled (19.7%) and uncontrolled asthma (9.8%). No statistically significant difference in asthma control was observed between the two treatment groups (P=0.057). Conclusion: Within the limitations of this retrospective cohort study, no statistically significant difference in asthma control was observed between salmeterol/fluticasone propionate and formoterol fumarate/budesonide.

Copyrights © 2026






Journal Info

Abbrev

jri

Publisher

Subject

Health Professions Medicine & Pharmacology

Description

Jurnal Respirologi Indonesia (JRI) is an online and printed scientific publication of the Indonesian Society of Respirology (ISR). The journal is published thrice-monthly within a year (January, April, July and October). The journal is focused to present original article, article review, and case ...