Journal of Biomedical Sciences and Health
Vol. 3 No. 1 (2026)

The Bacteriocin Potential of Lactic Acid Bacteria from Cincalok as an Antibacterial Against Shigella and Salmonella

Aprilia, Ineke (Unknown)
Pribadhi, Adhitya Naufal (Unknown)
Suwanto, Yustiana Arie (Unknown)
Widyaningrum, Ratna (Unknown)
Yana, Dian Rudy (Unknown)
Rofiah, Nurul Ummi (Unknown)



Article Info

Publish Date
19 Feb 2026

Abstract

Background: Lactic Acid Bacteria are a group of bacteria that have the ability to produce antimicrobial compounds called bacteriocins. Antibacterial of lactic acid bacteria proved effective in inhibiting pathogenic bacteria that cause infection in humans such as Shigella sp and Salmonella sp. Lactic acid bacteria can be found in fermented foods, one of which is fermented food typical of West Kalimantan, namely cincalok Aim: This study was to determine the antibacterial potential of cincalok lactic acid bacteria against Shigella sp and Salmonella sp Methods: This study used a true experimental, with the research design using a post test only control group design with data analyzed using SPSS to evaluate inhibition zone differences among three treatment groups: bacteriocin from Weissella sp. at 24 hours, Weissella sp. at 48 hours, and antibiotics (positive control) Results: The results obtained in the bacteriocin test from Weissella showed that there were differences in the inhibition zones formed, in Shigella sp the average values of the inhibition zones formed were W24 (24.4 mm), W48 (13.2 mm) and Cotrimoxazole (42.2 mm). while in Salmonella sp the average value of the inhibition zone formed is W24 (24.2 mm), W48 (12.8 mm) and Chloramphenicol (45 mm). Conclusion: Bacteriocins from LAB cincalok have an antibacterial effect on the growth of Shigella sp and Salmonella sp bacteria.

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Journal Info

Abbrev

jbsh

Publisher

Subject

Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health

Description

The Journal of Biomedical Sciences and Health (JBSH) accepts manuscripts in basic sciences and applied clinical research. It covers various fields of biomedical sciences, but is not limited to Medical sciences. Our journal accepts and publishes original articles and review articles that ...