Media Farmasi : Jurnal Ilmu Farmasi (Journal Of Pharmaceutical Science)
Vol. 23 No. 1 (2026): March 2026

Formulation and Evaluation of a Sunscreen Spray Containing Butterfly Pea Flower (Clitoria ternatea) Extract as a Natural Antioxidant

Rudi Kusuma, Nyoman (Unknown)
Sulistyani, Nanik (Unknown)
Sugihartini, Nining (Unknown)



Article Info

Publish Date
31 Mar 2026

Abstract

Butterfly pea flower (Clitoria ternatea) is rich in anthocyanins with recognized antioxidant activity; however, its application in spray-based sunscreen formulations and its effect on photoprotective performance remain insufficiently explored. This study aimed to formulate and evaluate a sunscreen spray containing butterfly pea extract (BPE) in combination with ethylhexyl methoxycinnamate and to determine the optimal extract concentration based on antioxidant activity, SPF value, and formulation stability. Five formulations were prepared: F0 (without BPE), F1 (0% BPE + 0.8% BHT), and F2–F4 containing 1%, 2%, and 3% BPE, respectively. Evaluations included DPPH radical scavenging activity, SPF determination, antibacterial testing, and physical quality assessment. The antioxidant activity of BPE in spray formulations showed moderate activity, with IC₅₀ values of 90.53±1.0, 87.50±1.9, and 86.94±1.4 μg/mL for 1%, 2%, and 3% concentrations, respectively, compared to 49.90±0.9 μg/mL for the pure extract. Although the antioxidant activity in formulations was lower than the pure extract due to dilution effects, increasing BPE concentration significantly improved SPF values (27.36±2.7; 29.42±1.1; 31.98±0.9; p<0.05). No significant difference was observed between 2% and 3% concentrations in both antioxidant and SPF evaluations. Therefore, 2% BPE was considered the optimal concentration, offering comparable efficacy with improved material efficiency for potential industrial production. All formulations met acceptable physical quality parameters, while antibacterial activity was not observed. This study demonstrates the feasibility of incorporating C. ternatea extract into sunscreen spray systems and provides a scientific basis for developing plant-based antioxidant-enhanced photoprotective formulations.

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Journal Info

Abbrev

Media-Farmasi

Publisher

Subject

Chemistry Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology

Description

Media Farmasi is a scientific journal published by the University of Ahmad Dahlan worked closely with Ikatan Apoteker Indonesia (IAI). Media Farmasi published two times a year, namely in March and September since 2002 with ISSN 1412-7946 and e-ISSN 2503-5223. The article published in the Journal ...