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Journal of Islamic Medicine

jim
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Published by Universitas Islam Negeri Maulana Malik Ibrahim Malang

ISSN : - EISSN : 25500074 DOI : https://doi.org/10.18860/jim

Core Subject : Health,

Medicine & Pharmacology

Journal of Islamic Medicine is a medical journal published twice a year in March and September by the School of Medicine, Faculty of Medicine and Medical Sciences, Universitas Islam Negeri Maulana Malik Ibrahim Malang.

Arjuna Subject : -

Articles 156 Documents

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PEMBERDAYAAN MASYARAKAT SUKU TENGGER NGADAS PONCOKUSUMO KABUPATEN MALANG DALAM MENGEMBANGKAN POTENSI TUMBUHAN OBAT DAN HASIL PERTANIAN BERBASIS â€œETNOFARMASIâ€ MENUJU TERCIPTANYA DESA MANDIRI Listiyana, Anik; Mutiah, Roihatul
Journal of Islamic Medicine Vol 1, No 1 (2017): Journal of Islamic Medicine
Publisher : Faculty of Medicine and Health Science, Universitas Islam Negeri Maulana Malik Ibrahim

Students as well as the next intellectual generation in society is not limited to academic obligations in the campus environment, but also should be useful in a variety of other functions in society. Students are also required to participate in community service through various forms of devotion. In this community service, lecturers with students to jointly work devotion in advancing knowledge and skills Tengger tribe in Ngadas Village District of Poncokusumo in developing the potential of medicinal plants and agricultural products based ethnopharmacy towards the creation of an independent village. Ngadas village is village with abundant natural resources, especially medicinal plants and agricultural products. Medicinal plants rare owned by the village is pronojiwo (Euchresta horsfieldii), pulosari (Alyxia reinwardtii), sintok (Cinnamomum sintoc), purwoceng (Pimpinella pruatjan), krangean (Litsea cububa Pers), flour muscles (Borreria laevis Griseb.), guava wer (Prunus persica Bl.), dringu (Acorus calamus L.). Medicinal plants have the potential to be developed and produced in large quantities in this village. Natural wealth of agricultural products is also very abundant in this village include potato, cassava, sweet potatoes and celery. But not taken into ready to eat foods products. Performed community service on 19 November 2016 in the village hall Ngadas. The activities carried out in the form of workshops begins with exposure of the material on the benefits and applications of potential medicinal plants that become local wisdom in Tengger tribe and then followed by demo making products. The product are rub medicine guava wer,Â muscle flour, starfruit herbal drinks and bajigur. Participants consisted of PKK Ngadas village. Good response shown by them with great enthusiasm when exposure of the material provided and when making products. In the future, this mentoring program to be developed into entrepreneurial activities of local communities to improve their welfare.

Pengaruh Pemberian Jus Tomat (Solanum lycopersicum) terhadap Jumlah Sel Radang di Alveolus Tikus Wistar (Rattus norvegicus) yang Dipapar Asap Rokok Kretek Subkronik Mustika, Dewi; Subandi, Subandi
Journal of Islamic Medicine Vol 2, No 1 (2018): Journal of Islamic Medicine
Publisher : Faculty of Medicine and Health Science, Universitas Islam Negeri Maulana Malik Ibrahim

Asap rokok mengandung radikal bebas yang dapat menyebabkan proses inflamasi pada saluran nafas. Peningkatan jumlah sel radang pada alveolus paru dapat semakin meningkatkan kondisi stres oksidatif dikarenakan sel radang juga memicu timbulnya radikal bebas. Oleh karena itu, pemberian antioksidan diharapkan dapat mengurangi proses keradangan pada alveolus paru. Tujuan dari penelitian ini untuk membuktikan pengaruh pemberian jus tomat, yang mengandung likopen, betakaroten, dan vitamin c, terhadap penurunan jumlah sel radang alveolus tikus Wistar jantan yang dipapar asap rokok subkronik. Pemaparan asap rokok dilakukan selama 9 minggu menggunakan smoking pump, dilanjutkan dengan pemberian jus tomat dengan dosis 1,15; 2,3; dan 4,6 ml/tikus perhari selama 3 minggu. Setelah 12 minggu, jaringan paru setiap tikus diambil, kemudian dibuat sediaan histopatologi dengan pengecatan HE. Sediaan diamati menggunakan mikroskop pada 10 lapang pandang untuk dilakukan penghitungan jumlah sel radang (neutrofil, limfosit, makrofag) yang terdapat pada septa interalveolaris. Data dianalisis menggunakan One-Way ANOVA dilanjutkan uji Post hoc Tukey. Hasil penelitian menunjukkan bahwa pemberian jus tomat dapat menyebabkan penurunanÂ jumlah sel radang di alveolus pada ketiga dosis yang diberikan (p=0,000). Hasil uji korelasi Pearson menunjukkan bahwa semakin tinggi dosis jus tomat (0; 1,15; 2,3; 4,6 ml/hari) maka akan semakin menurunkan jumlah sel radang di alveolus (r= -0,868; p=0,000). Dari penelitian ini dapat disimpulkan bahwa pemberian jus tomatÂ setelah paparan asap rokokÂ dapat menurunkan jumlah sel radang di alveolus.

Studi Efikasi dan Keamanan Ekstrak Akar dan Daun Calotropis gigantea Terhadap Sel Kanker Kolon dan Sel Kanker Payudara Secara In Vitro Mutiah, Roihatul
Journal of Islamic Medicine Vol 1, No 2 (2017): Journal of Islamic Medicine
Publisher : Faculty of Medicine and Health Science, Universitas Islam Negeri Maulana Malik Ibrahim

Development of phytopharmaca for cancer until now has become a major step in overcoming the failure of cancer therapy. Calotrophis gigantea is one of the scientifically proven plants both in vitro and in vivo as a chemopreventive agent. This study aims to explain the efficacy and safety of Calotropis gigantea leaf extract (EDCG) and Calotropis gigantea root extract (EACG) on NIH3T3 cell, colon cancer cell WiDr and T47D breast cancer cells. From the analysis of MTT and Selectivity Index (SI) analysis showed that ethanol extract of leaf Calotropis gigantea (EDCG) can inhibit selective growth of selective colon cancer cells (SI 3) but not selective in inhibiting the growth of breast cancer cells T47D (SI 3 ). Calotropic gigantea (EACG) root ethanol extract is not selective in inhibiting the growth of colon cancer cells WiDr and breast cancer cells T47D (SI 3). Therefore EDCG can be recommended as a Phytopharmaca candidate with further proof through clinical trials.

GAGAL JANTUNG KIRI DAN HIPERTENSI PULMONAL Sargowo, Djanggan
Journal of Islamic Medicine Vol 1, No 1 (2017): Journal of Islamic Medicine
Publisher : Faculty of Medicine and Health Science, Universitas Islam Negeri Maulana Malik Ibrahim

In patients with left heart failure, pulmonary hypertension and right ventricular dysfunction is a common condition and has important implications in the development of disease, disability and death, so it required special attention. Pulmonary hypertension is the most common form with approximately 65-80% of cases. Although today is already highly developed understanding of the pathophysiology and clinical assessment, as well as setting the hemodynamic definition and classification of pulmonary hypertension in left heart failure, but the interrelation hemodynamics in pulmonary hypertension combination of pre- and post-capillary is still very complex, and there is no evidence-based recommendations the handling of pulmonary hypertension is left heart failure. Here, we will discuss the prevalence and significance of pulmonary hypertension and cardiac dysfunction Right in patients with both heart failure with ejection fraction decreased, as well as heart failure with ejection fraction, as well as provides an overview of the pathophysiology of the complex due to the interaction of cardiopulmonary left heart failure, which can supports the evolution of the phenotype of the left ventricle into the right ventricle phenotype through the travel history of heart failure. Next, we will discuss fenoitp pulmonary hypertension by combining the clinical context, the assessment of non-invasive and invasive hemodynamic variables in a structured diagnostic assessment.

PENGARUH TERAPI BEKAM TERHADAP PENURUNAN TEKANAN DARAH PADA KEGAWAT DARURATAN HIPERTENSI DI PUSKESMAS PADEMAWU PAMEKASAN Nur, Muhammad
Journal of Islamic Medicine Vol 2, No 1 (2018): Journal of Islamic Medicine
Publisher : Faculty of Medicine and Health Science, Universitas Islam Negeri Maulana Malik Ibrahim

Hipertensi atau tekanan darah tinggi, adalah meningkatnya tekanan darah atau kekuatan menekan darah pada dinding rongga di mana darah itu berada. Tekanan Darah Tinggi (hipertensi) adalah suatu peningkatan tekanan darah di dalam arteri. (Hiper artinya Berlebihan, Tensi artinya tekanan/tegangan; jadi, hipertensi adalah Gangguan sistem peredaran darah yang menyebabkan kenaikan tekanan darah diatas nilai normal. Tekanan darah ditulis sebagai tekanan sistolik garis miring tekanan diastolik, misalnya 120/80 mmHg, dibaca seratus dua puluh per delapan puluh. Sejalan dengan bertambahnya usia, hampir setiap orang mengalami kenaikan tekanan darah, tekanan sistolik terus meningkat sampai usia 80 tahun dan tekanan diastolik terus meningkat sampai usia 55-60 tahun, kemudian berkurang secara perlahan atau bahkan menurun drastis.Berdasarkan hasil uji Wilcoxon Signed Rank Test (WSRT) didapatkan hasil dari gambar ranks bahwa nilai sum ranks berpihak positive dengan nilai sum : 45.00 artinya ada peningkatan terhadap tingkat keberhasilan antara sebelum Terapibekam dan sesudah dilakukan tindakan Terapibekam, dan selanjutnya dikonsultasikan dengan nilai sum table Wilcoxon. Sedangkan berdasarkan hasil gambar test statistic didapatkan pula bahwa nilai Asymp.Sig. (2-tailed) : 0,003, dengan nilai probability (Î±) 0,05, artinya nilai Asymp.Sig. (2-tailed) 0,003 nilai probability 0,05.Kesimpulan pada penelitian ini menunjukkan Terapibekam dapat menurunkan tekanan darah pada pasien yang dilakukan tindakan pemas Terapibekam sehingga dapat direkomendasikan bahwa Terapibekam merupakan salah satu cara yang dapat digunakan untuk menurunkan tekanan darah tinggi yang menunjang intervensi keperawatan dan medisÂ Â Â

Pengaruh Kitosan Terhadap Jumlah Osteoklas dan Osteoblas Pada Tikus Galur Wistar Model Menopause Nur, Muhammad
Journal of Islamic Medicine Vol 1, No 2 (2017): Journal of Islamic Medicine
Publisher : Faculty of Medicine and Health Science, Universitas Islam Negeri Maulana Malik Ibrahim

Chitosan is one of the most abundant and dispersed polymers in nature. It has a rapid healing effect for tissues and has an effect on bone remodeling. The purpose of this study was to prove that giving chitosan influenced the decrease of osteoclast number and increasing number of osteoblasts in female mice of wistar strain of ovariectomy menopause model.This study used a posttest only control group design. The total sample of 30 rats divided into three groups was randomized, osteoporosis was made with the menopausal model which was performed ovariectomy in the positive control group and the treatment group then in the treatment group was given chitosan extract of single dose of 45 mg / day via Nasogastric Tube (NGT). K1 was a negative control group (without ovariectomy and without chitosan), K2 was a positive control group (with no chitosan ovariectomy), K3 was the treatment group (ovariectomy and chitosan 45 mg / day).The results showed significant differences in the number of osteoblasts between K1 and K3, K2 with K3, and no significant differences were found in the K1 group with K2. While the number of osteoclasts showed that there were significant differences in K1 group with K2 and no significant difference was found in K1 group with K3, K2 with K3.Conclusions in this study showed that 45 mg / day of chitosan doses could significantly increase osteoblast counts in menopause female white rats and decrease the number of osteoclasts performed by ovariectomy with chitosan administration.

PERANAN ZINC PADA PENANGANAN KASUS PENYAKIT DIARE YANG DIALAMI BAYI MAUPUN BALITA Riskiyah, Riskiyah
Journal of Islamic Medicine Vol 1, No 1 (2017): Journal of Islamic Medicine
Publisher : Faculty of Medicine and Health Science, Universitas Islam Negeri Maulana Malik Ibrahim

In Indonesia, diarrhea still is one of top problem public health for causing morbidity andÂ many deaths. All age groups can be attacked by diarrhea, but severe disease with high mortality especially in infants and toddlers. WHO and UNICEF recommend about management of diarrhea in children namely by adding a supplementation of zinc (Zn) on oral rehydration therapy. Zinc functions in the immune system as a second messenger in signal transduction, cell immunity and nutritional immunity. Zinc also plays an important role in reducing the risk and severity of diarrhea. From some research shows that the effects of therapeutic zinc supplementation can reduce the duration of diarrhea, stool output and stool frequency. The supplementation of 20 mg of zinc per day on the eradication of child diarrhea are less than 5 years and 10 mg per day for infants less than 6 months for 10-14 days. The beneficial effects of zinc supplementation in diarrhea that can speed up the regeneration of the epithelium lining the intestine, increasing the absorption of water and electrolytes in the intestine, increase enzyme levels enterocyte brush-border, and enhance the immune response that can speed up clearance of pathogens from the gut.

METODE SLOW SAND FILTER DAN PENGUKURAN MPN COLIFORM SEBAGAI UPAYA PENINGKATAN KUALITAS AIR SUNGAI DI PEKAPURAN RAYA BANJARMASIN Herlina, Sri
Journal of Islamic Medicine Vol 2, No 1 (2018): Journal of Islamic Medicine
Publisher : Faculty of Medicine and Health Science, Universitas Islam Negeri Maulana Malik Ibrahim

Sungai Pekapuran Raya Banjarmasin merupakan salah satu kawasan pinggiran sungai yang padat penduduk, saat musim kemarau kondisi sungai terlihat dangkal dipenuhi tumpukan sampah, berwarna kecoklatan dan keruh. Penelitian ini bertujuan untuk mengukur MPN Coliform air sungai Pekapuran Raya dan melakukan pembinaan pada kelompok ibu Antasan Segra tentang peningkatan kualitas air sungai menggunakan metode slow sand filter (SSF). Desain penelitian adalah observasional analitik dengan pendekatan cross sectional, melibatkan 38 responden secara total sampling. Teknik pengumpulan data dan analisis masalah dilakukan dengan pendekatan PRA (Participation Rural Appraisal). Bahan yang digunakan dalam pengolahan air menggunakan metode SSF seperti pasir, arang aktif, sabut kelapa (Ijuk) dan batu koral/kerikil serta busa penyangga yang tersedia cukup banyak disekitar rumah warga. Hasil pengukuran MPN Coliform pada air sungai Pekapuran Banjarmasin menunjukkan positif terdapat bakteri Coliform sebesar 240/100 ml sampel, sedangkan ambang baku mutu yang dipersyaratkan yaitu 100 sel/100 ml air.Â Â Â Â Â Â Â Â Â Â Â Analisis kualitas air secara fisik menggunakan slow sand filter menunjukkan tingkat kekeruhan air sungai dari berwarna kecokelatan menjadi bening setelah penyaringan, model ini memudahkan masyarakat memanfaatkan air sungai menjadi air bersih karena lebih sederhana, murah, serta aman.

MALARIA PADA KEHAMILAN DAN KONSEKUENSINYA PADA IBU DAN JANIN Rahmah, Zainabur
Journal of Islamic Medicine Vol 1, No 1 (2017): Journal of Islamic Medicine
Publisher : Faculty of Medicine and Health Science, Universitas Islam Negeri Maulana Malik Ibrahim

Malaria is an infectious disease remains a major health problem in the world. Malaria attacks without differentiating individual age and sex of pregnant women are no exception. Pregnant women have a risk of malaria by Plasmodium parasites is more severe in comparison with non-pregnant women. When a pregnancy will occur immunosuppression both humoral and cellular purpose of this paper is to discuss the mechanism of occurrence of malaria in pregnancy and its consequences on the mother and fetus. Parasite adhesion receptors Chondroitin Sulfate A (CSA) and Hyaluronic Acid (HA) in the placenta can trigger an inflammatory process involving the secretion of cytokines. Inflammatory component that appears after the accumulation of parasites in the placenta is associated with immune pathology in the Pregnancy-Associated Malaria (PAM), such as thickening of the membrane cytotrophoblasts that disrupt blood flow, inhibiting the transfer of IgG across the placenta and the exchange of nutrients from mother to fetus, causing lesions in the placenta. Malaria infection during pregnancy is a process of mediation by protein cytoadherence in Plasmodium falciparum erythrocyte membrane protein-1 (PfEMP-1) encoded by genes that bind to receptors on Var2CSA this causes placental sequestration of infected erythrocytes on endothelial cells resulting in anemia in pregnant while on fetus causes low birth weight, premature birth and stillbirth.

Gangguan Tidur pada Lanjut Usia Sunarti, Sri; Helena, Helena
Journal of Islamic Medicine Vol 2, No 1 (2018): Journal of Islamic Medicine
Publisher : Faculty of Medicine and Health Science, Universitas Islam Negeri Maulana Malik Ibrahim

Sekitar 50% orang lanjut usia mengalami kesulitan tidur gangguan tidur memberikan pengaruh negatif yang signifikan pada kesehatan fisik dan mental, terutama pada orang lanjut usia. Gangguan tidur pada orangtua dapat bersifat akut atau kronis, dapat disebabkan karena faktor intrinsik atau gangguan tidur primer atau sekunder akibat penyakit lain, gangguan psikologis atau fisik, faktor lingkungan dan efek samping obat. Gangguan tidur dapat mempengaruhi kualitas hidup pada orangtua, menurunkan status imunologi, gangguan hormonal dan endokrinologi, serta penurunan fungsi kognitif. Manajemen untuk gangguan tidur ini meliputi terapi non-farmakologis dan farmakologis. Perubahan perilaku dan modifikasi diet pada beberapa penyebab gangguan tidur terbukti efektif. Intervensi non-farmakologis seperti sleep hygiene dan terapi perilaku kognitif merupakan terapi lini pertama pada berbagai gangguan tidur.

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Zainabur Rahmah

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Jalan Ir. Soekarno No.34 Dadaprejo, Batu, Jawa Timur, Indonesia

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Jawa timur

INDONESIA

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Home Page

OAI Link

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Contact Name Zainabur Rahmah

Contact Email medicaljournal@uin-malang.ac.id

Phone +6285259506000

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Editorial Address Jalan Ir. Soekarno No.34 Dadaprejo, Batu, Jawa Timur, Indonesia

Location Kota malang, Jawa timur INDONESIA

Abstract

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Abstract

Abstract

Abstract

Abstract

Contact Name
Zainabur Rahmah

Contact Email
medicaljournal@uin-malang.ac.id

Phone
+6285259506000

Journal Mail Official
medicaljournal@uin-malang.ac.id

Editorial Address
Jalan Ir. Soekarno No.34 Dadaprejo, Batu, Jawa Timur, Indonesia

Location
Kota malang,

Jawa timur

INDONESIA