CRJIM (Clinical and Research Journal in Internal Medicine)
Vol. 7 No. 1: Volume 7 No 1, May 2026

The Comparative Value of MLR And NLR to CIMT Between HD and CAPD Patients

Baridwan, Fakhri (Unknown)
Samsu, Nur (Unknown)
Winoto, Eden Suryoiman (Unknown)



Article Info

Publish Date
29 May 2026

Abstract

Background: Research about the comparison of monocyte lymphocyte ratio (MLR) and neutrophil lymphocyte ratio (NLR) on Carotid Intima-Media Thickness (CIMT) between Hemodialysis (HD) and Continuous Ambulatory Peritoneal Dialysis (CAPD) patients is still very limited, therefore further research is needed. Aim: This study aims to investigate the relationship between MLR and NLR values and CIMT in HD and CAPD patients. Method: A cross-sectional observational study was conducted on 97 dialysis patients (52 HD and 45 CAPD patients) at Saiful Anwar General Hospital, Indonesia. Participants were over 18 years old, on dialysis for at least three months (HD at least twice weekly), and physically independent. Critically ill and pregnant patients were excluded. Statistical analysis was performed using Mann-Whitney test to see the difference of NLR and MLR between the two groups, Spearman test was used to analyse the correlation of NLR and MLR to CIMT in HD and CAPD. Results: This study revealed that CAPD patients had higher NLR values compared to HD patients (MD: 0.63; 95%CI: 0.07 - 1.15; p: 0.0253) and there was a significant association between MLR and increased Carotid Intima-Media Thickness (CIMT) in CKD patients undergoing CAPD (r: 0.3543; 95%CI: 0.05896 - 0.5927; p: 0.0169).   Conclusion: Our study underscores higher NLR values were found in CAPD patients compared to HD patient and the significant association between MLR values and CIMT in CAPD patients.

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Journal Info

Abbrev

crjim

Publisher

Subject

Education Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Other

Description

Clinical and Research Journal in Internal Medicine is the official open access journal of Internal Medicine Research Center, Department of Internal Medicine, Faculty of Medicine, Universitas Brawijaya, Malang, Indonesia. It publishes articles two times per year. It is a peer reviewed publication of ...