<![CDATA[The development of neuroscience has significantly influenced contemporary educational studies, particularly in understanding brain development and learning processes. However, studies integrating neuroembryology and Islamic education remain limited, especially in constructing a neuro-pedagogical framework based on brain development. This study aims to analyze the integration of neuroembryology and Islamic education in developing a brain development-based neuro-pedagogical framework. This research employed a qualitative approach using a Systematic Literature Review (SLR) method guided by the PRISMA framework. Data were collected from scientific articles indexed in Scopus, ScienceDirect, SpringerLink, DOAJ, and Google Scholar published between 2019 and 2025. A total of 42 relevant articles were analyzed using content analysis and thematic synthesis techniques. The findings reveal that neuroembryology has a significant relationship with learning readiness, emotional regulation, cognitive development, and character formation. The study also found that the principles of brain-based learning are substantially aligned with Islamic educational values such as fitrah, tarbiyah, ta’dib, tazkiyah, and akhlaq development. Based on the synthesis results, this study proposes a conceptual framework of Islamic neuro-pedagogy integrating neuroembryology, brain-based learning, and Islamic educational values into a holistic learning model. This research contributes theoretically to the integration of neuroscience and Islamic education and practically to the development of curriculum design, learning strategies, and neuroscience-based Islamic educational practices.Keyword: Neuroembryology, Islamic education, neuroscience, brain-based learning, neuro-pedagogy.]]>
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