Jurnal Sains Farmasi dan Kesehatan
Vol. 4 No. 1 (2026): Mei-Agustus

Artikel Review : Pengaruh Penyalutan Terhadap Karakteristik Fisikokimia Tablet Salut Gula atau Enterik

Nisful Lailatun Nadiroh (Universitas Anwar Medika)
Dwi Roisiyah (Universitas Anwar Medika)
Salsabiila Wina Delia (Universitas Anwar Medika)
Najwa Firida Rahma (Universitas Anwar Medika)
Adela Gerlani Bria (Universitas Anwar Medika)
Rusdiana Tri Septiarini (Universitas Anwar Medika)
Jihan Fahiroh Nur Arifin (Universitas Anwar Medika)
Dewi Rahmawati (Universitas Anwar Medika)
Yani Ambari (Universitas Anwar Medika)
Dzakiya Zhihrotul Wida (Universitas Anwar Medika)



Article Info

Publish Date
06 Jun 2026

Abstract

Tablet coating is one of the pharmaceutical technologies that plays an important role in improving the physicochemical characteristics and stability of tablet preparations. This study aims to comprehensively review the effect of coating processes on the physicochemical characteristics and stability of tablets, including mechanical properties, dissolution profiles, and active substance stability during storage. The method used is a literature review of 8 scientific journals obtained from Google Scholar, PubMed, PerpusNas, and ResearchGate databases, published within the last 5–10 years. The results showed that the coating process significantly affected physicochemical characteristics including hardness, friability, disintegration time, dissolution profile, and drug release. In terms of stability, coating protected active substances from environmental influences such as humidity, oxidation, and gastric acid degradation. Among the types of coating studied, enteric coating proved to be the most effective method as it provided maximum protection for acid-sensitive drugs and specifically controlled drug release in the intestine, thereby positively impacting bioavailability and therapeutic efficacy. Sugar coating also contributed to improving physical properties and protecting tablets during storage and distribution. Therefore, selection of appropriate coating type and composition is a critical factor in producing quality, stable, and therapeutically effective tablet preparations.

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Journal Info

Abbrev

jfkes

Publisher

Subject

Medicine & Pharmacology Neuroscience Nursing Physics Public Health Veterinary

Description

Jurnal Sains Farmasi dan Kesehatan (JFKES) E-ISSN : 3024-9368 is an open access journal which is a media of research publication and review article on all aspects of pharmaceutical science that is innovative, creative, original and based on scientific. Articles published in this journal include ...