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All Journal Obat: Jurnal Riset Ilmu Farmasi dan Kesehatan Jurnal Sains Farmasi dan Kesehatan
Salsabiila Wina Delia
Universitas Anwar Medika
Health Professions Medicine & Pharmacology Neuroscience Nursing Physics Public Health Veterinary

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Artikel Review : Pengaruh Penyalutan Terhadap Karakteristik Fisikokimia Tablet Salut Gula atau Enterik Nisful Lailatun Nadiroh; Dwi Roisiyah; Salsabiila Wina Delia; Najwa Firida Rahma; Adela Gerlani Bria; Rusdiana Tri Septiarini; Jihan Fahiroh Nur Arifin; Dewi Rahmawati; Yani Ambari; Dzakiya Zhihrotul Wida
Jurnal Sains Farmasi Dan Kesehatan Vol. 4 No. 1 (2026): Mei-Agustus
Publisher : CV. ITTC INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62379/jfkes.v4i1.4596

Abstract

Tablet coating is one of the pharmaceutical technologies that plays an important role in improving the physicochemical characteristics and stability of tablet preparations. This study aims to comprehensively review the effect of coating processes on the physicochemical characteristics and stability of tablets, including mechanical properties, dissolution profiles, and active substance stability during storage. The method used is a literature review of 8 scientific journals obtained from Google Scholar, PubMed, PerpusNas, and ResearchGate databases, published within the last 5–10 years. The results showed that the coating process significantly affected physicochemical characteristics including hardness, friability, disintegration time, dissolution profile, and drug release. In terms of stability, coating protected active substances from environmental influences such as humidity, oxidation, and gastric acid degradation. Among the types of coating studied, enteric coating proved to be the most effective method as it provided maximum protection for acid-sensitive drugs and specifically controlled drug release in the intestine, thereby positively impacting bioavailability and therapeutic efficacy. Sugar coating also contributed to improving physical properties and protecting tablets during storage and distribution. Therefore, selection of appropriate coating type and composition is a critical factor in producing quality, stable, and therapeutically effective tablet preparations.
Artikel Review Fitokimia : Efektivitas Maserasi Soxhletasi sebagai Metode Ekstraksi Miftakhul Rokhmah; Amanda Rafina Modesty; Auliya Ika Putri; Salsabiila Wina Delia; Adelia Girlani Bria; Maria Delsiana Ndun; Elsa Tectona Zuliyanti; Renata Setya Agustin; Petrus Paulus Bria; A’Yunil Hisbiah; Ivan Charles S.Klau; Arista Wahyu Ningsih
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 4 No. 1 (2026): Januari: OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v4i1.2060

Abstract

The Soxhlet extraction method uses repeated heating and solvent circulation to separate substances from mixtures, producing more extract faster than maceration with less solvent. However, this method requires pure solvents and is not suitable for thermolabile compounds as they can be degraded by heat. Soxhlet extraction is more effective for limited quantities of dry and fine herbal materials. This method is widely used to extract phytochemical compounds such as flavonoids, tannins, and curcumin, and has potential in cosmetic raw materials, herbal medicines, and antioxidant products. Although it uses more energy, this technique is efficient and continuous. Modern innovations such as combining it with Ultrasonic Assisted Extraction (UAE) or environmentally friendly microextraction are expected to increase extraction efficiency while reducing the use of organic solvents. Modifications to Soxhlet, including automation and assistive technologies such as high pressure, ultrasound, and microwaves, open up opportunities for commercialization and further research with more optimal results and more practical operations. The modified Soxhlet is considered a “panacea” in extraction due to the significant performance improvements achieved.
Co-Authors Adela Gerlani Bria Adelia Girlani Bria Amanda Rafina Modesty ARISTA WAHYU NINGSIH Auliya Ika Putri A’Yunil Hisbiah Dewi Rahmawati Dwi Roisiyah Dzakiya Zhihrotul Wida Elsa Tectona Zuliyanti Ivan Charles S.Klau Jihan Fahiroh Nur Arifin Maria Delsiana Ndun Miftakhul Rokhmah Najwa Firida Rahma Nisful Lailatun Nadiroh Petrus Paulus Bria Renata Setya Agustin Rusdiana Tri Septiarini Yani Ambari