Jejak digital: Jurnal Ilmiah Multidisiplin
Vol. 2 No. 4 (2026): JUNI-JULI

Disregulasi Respon Imun pada Kanker Payudara: Tinjauan Epidemiologi, Subtipe Molekuler, dan Terapi

Maula Syakira (Universitas Syiah Kuala)
Nisa Ulmafhigrah (Universitas Syiah Kuala)
Firdus Firdus (Universitas Syiah Kuala)
Rosnizar Rosnizar (Universitas Syiah Kuala)



Article Info

Publish Date
07 Jun 2026

Abstract

Breast cancer is the disease with the highest mortality rate in women worldwide. Breast cancer development is influenced not only by the intrinsic characteristics of tumor cells but also by the complex interactions between cancer cells, the immune system, and components of the tumor microenvironment (TME). Dysregulation of the immune response plays a crucial role in disease progression through various mechanisms, including immunosuppression, immune evasion, and altered immune cell function. This article aims to comprehensively examine the mechanisms of immune response dysregulation in breast cancer based on the latest scientific literature. The method used is a literature review by reviewing various relevant research articles and review articles regarding breast cancer molecular subtypes, TME characteristics, the role of immune cells, and factors influencing the immune response in breast cancer. The results of this study indicate that breast cancer molecular subtypes have distinct immunological characteristics that influence disease progression and therapeutic response. A deeper understanding of these mechanisms is expected to support the development of more effective therapeutic strategies, particularly immunotherapy tailored to the patient's biological characteristics.

Copyrights © 2026






Journal Info

Abbrev

jejakdigital

Publisher

Subject

Economics, Econometrics & Finance Education Languange, Linguistic, Communication & Media Social Sciences Other

Description

Jurnal Ilmiah Multidisiplin adalah jurnal elektronik dan cetak Open Access Journal yang diterbitkan oleh Indo Publishing setiap 6 kali dalam setahun menyediakan forum untuk mempublikasikan artikel penelitian asli, artikel review dari kontributor, dan berita teknologi baru mencangkup multidisiplin ...