Type 2 diabetes is a major cause of illness and death. Long suffering from diabetes is often associated with complications such as neuropathy. Complications usually begin to arise after the client has suffered from DM for more than 10 years. Lifestyle modification is a fundamental management approach that can prevent or delay the development of prediabetes into diabetes, as well as reduce the risk of microvascular and macrovascular diseases. The purpose of this study was to review the effectiveness of some interventions on minimizing progression to diabetes in high-risk patients or progression to clinical outcomes (such as cardiovascular disease and death) in patients with type 2 diabetes. Data Sources in tihis study was from research on lifestyle interventions in type 2 diabetes mellitus published between 2007-2022 in online article databases PubMed, Proquest, Geogle Schoolar, Sci Hub and Sciencedirect. The data collection technique was by entering keywords into the database, the keywords used were: interventions AND Type 2 Diabetes Melitus; Lifestyle Diabetes Melitus AND Prevent Complications, Interventions AND Modification Lifestyle. Several interventions were found to prevent complications in patients with type 2 diabetes mellitus, starting from self-empowerment interventions, family empowerment, health belief models, cultural approaches, and others. Comprehensive lifestyle interventions effectively decrease the incidence of type 2 diabetes in high-risk patients and its complications. In patients who already have type 2 diabetes, there is no evidence of reduced all-cause mortality and insufficient evidence to suggest benefit on cardiovascular and microvascular outcomes
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