Jurnal Pengmas Kestra (JPK)
Vol. 6 No. 1 (2026): Jurnal Pengmas Kestra (JPK)

Workshop on Enhancing Diagnostic Accuracy: Strategies to Mitigate Lipemic Interference in Urea and Creatinine Testing Using Alpha-Cyclodextrin

Siti Ramadhani (Institut Kesehatan Medistra Lubuk Pakam)
Riri Safitri (Institut Kesehatan Medistra Lubuk Pakam)
Nur Afni Heryanti Octavia (Institut Kesehatan Medistra Lubuk Pakam)



Article Info

Publish Date
01 Jul 2026

Abstract

The quality of blood samples dictates the validity of clinical laboratory testing. Lipemic serum conditions frequently cause analytical issues due to high lipid particles that interfere with photometer readings in chemistry analyzers. This community service (PkM) program, formatted as a workshop, was implemented to broaden the knowledge and technical proficiency of laboratory personnel. The event involved 30 students from the Medical Laboratory Technology program as participants. The implementation included interactive lectures, visual demonstrations, in-depth discussions on clinical chemistry principles, and hands-on sample management practices in the laboratory. Educational and training materials were specifically designed to ensure that participants could effectively resolve lipid interference and understand the function of alpha-cyclodextrin as a safe clearing agent that does not alter analyte concentrations. The results demonstrated tangible progress among participants in detecting analytical interference caused by lipemia, evidenced by a 33.5-point average increase in cognitive knowledge scores and a 95.0% participant satisfaction rate. Participants are now capable of executing correct pre-analytical steps using alpha-cyclodextrin and obtaining more accurate urea and creatinine measurements. This program underlines the importance of integrating technical problem-solving into human resource competency enhancement activities in the laboratory. Improving participants' understanding of managing problematic specimens contributes directly to enhancing the quality of clinical chemistry examination results and supports the creation of professional, precise, and reliable healthcare services for the community..

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Journal Info

Abbrev

JPK

Publisher

Subject

Health Professions Nursing Public Health

Description

Publikasi jurnal ini bertujuan untuk menyebarluaskan pemikiran atau gagasan konseptual dan hasil penelitian yang telah dicapai di bidang pengabdian kepada masyarakat. Jurnal Pengmas Kestra (JPK), secara khusus menitikberatkan pada permasalahan pokok dalam pengembangan keilmuan bidang pengabdian ...