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All Journal Jurnal Kesmas dan Gizi (JKG) Jurnal Pengmas Kestra (JPK) Medistra Medical Journal (MMJ)
Siti Ramadhani
Institut Kesehatan Medistra Lubuk Pakam
Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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The Role of Quality Management in Ensuring the Accuracy of Clinical Laboratory Teest Result at Grandmed Lubuk Pakam Hospital Siti Ramadhani; Ahmad Hafizullah Ritonga; Basyariah Lubis
JURNAL KESMAS DAN GIZI (JKG) Vol. 8 No. 2 (2026): Jurnal Kesmas dan Gizi (JKG)
Publisher : Fakultas Kesehatan Masyarakat Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/gx956d91

Abstract

Clinical laboratories hold an important role in modern healthcare services because approximately 60–70% of medical decisions depend on laboratory examination results. Therefore, the accuracy of these results becomes a fundamental aspect that must be maintained through the implementation of comprehensive quality management. Laboratory quality is strongly influenced by three main phases, namely the pre-analytic, analytic, and post-analytic phases. Various studies show that most errors occur in the pre-analytic phase, such as incorrect patient identification, improper specimen collection, and unsuitable storage conditions. Thus, the ability of laboratory personnel to apply standard operating procedures (SOPs) becomes a crucial factor in efforts to improve result accuracy. This study aims to analyze the relationship between human resource competence, the implementation of Quality Assurance (QA), and Quality Control (QC) with the accuracy of laboratory examination results at Grandmed Lubuk Pakam Hospital. The research used a quantitative approach with a cross-sectional design and involved 30 laboratory personnel. Data were obtained through structured questionnaires and analyzed using the Spearman’s rho correlation test. The results showed a very strong relationship between human resource competence and examination accuracy (r = 0.938; p < 0.001), QA and accuracy (r = 1.000; p < 0.001), as well as QC and examination accuracy (r = 0.984; p < 0.001). These findings emphasize that good quality management—supported by competent laboratory personnel and consistent implementation of QA and QC—plays a major role in ensuring the accuracy of examination results. Regular quality evaluations are necessary to improve patient safety and support more accurate clinical decision-making.ongoing basis through improving laboratory personnel competence, ensuring consistent application of QA and QC at all stages of laboratory testing, and conducting regular quality evaluations to support patient safety and accurate clinical decision-making.
Analysis Of The Result Of DNA (Deoxyribonucleic Acid) Electrophoresis On Vaginal Mucosal Swabs With Cervical Cancer Patients Siti Ramadhani; Vincentia Ade Rizky; Sa'adah Siregar
Medistra Medical Journal (MMJ) Vol 2 No 1 (2024): Medistra Medical Journal (MMJ)
Publisher : Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/mmj.v2i1.2371

Abstract

Background: Cervical cancer is one of the second-highest sexually transmitted diseases in the world, accounting for 13% of the total 22% of deaths caused by non-communicable diseases. Today there have been many developments about cervical cancer diagnosis methods especially in early detection aimed at recognizing cervical cancer at an earlier stage, including molecular biology detection using PCR tools and electrophoresis. Objective: To identify the results of DNA electrophoresis in vaginal mucosal swabs with cervical cancer. Method : The research method used is experimental. Results: Based on the results of a study using a documentary gel, 2 samples of HPV DNA tape were detected, it was tested positive because there was 450 bp DNA tape and 4 samples of negative results were obtained. Conclusion: The frequency distribution of respondents from 6 samples by using electrophoresis and focumerary gel as readers detected 2 positive samples. A positive result is expressed if a result in the documentary gel is found to be a DNA band. The size of the DNA ribbon produced with the DNA marker markers is at 450 bp, according to the sample target. This shows that the DNA bands in the sample are about 450 bp in size.
Comparison of Urea and Creatinine Levels in Lipemic Serum and Lipemic Serum Treated with Alpha-Cyclodextrin Siti Ramadhani; Vitra Missi Agatha Agatha; Riri Safitri
Medistra Medical Journal (MMJ) Vol 3 No 2 (2026): Medistra Medical Journal (MMJ)
Publisher : Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/nvvhe105

Abstract

Background: Turbid (lipemic) serum is usually caused by an increase in lipoprotein levels so that turbidity can be clearly seen by the eye. The accumulation of lipoprotein particles causes lipemia in serum, but not all types of lipoproteins. The largest particles, namely chylomicrons with a size of 70-1000 nm, are the main cause of turbidity in serum samples. However, the accumulation of small particles, high density lipoprotein (HDL), low density lipoprotein (LDL) does not produce lipemic serum. Objective: To determine the differences in the results of the examination of urea creatinine levels in lipemic serum and lipemic serum given alpha cyclodextrin, and to determine how to properly handle lipemic serum.  Method: The type of research used in this method is a quantitative experiment with a one group pre and post test design plan. one group pre and post test design is quasi experimental. Results: normality test results show that the data is not normally distributed because the sig value. 0.05, then the research continued with the Friedman's ANOVA test. In the Friedman's ANOVA analysis carried out, the Asyms value was obtained. sig. (0.201) 0.05 Conclusion: So it can be concluded that there is no significant difference between lipemic serum and lipemic serum treated with alpha cyclodextrin in checking urea and creatinine using a chemical analyzer. From the analysis obtained through the Friedman ANOVA test, a sig value of 0.05 was obtained, which means there was no difference in the urea creatinine value in lipemic serum with lipemic serum that was given alpha cyclodextrin. Alpha cyclodextrin can be useful for handling lipemic samples, because alpha cyclodextrin is ale to detect lipids that cause lipemic
Workshop on Enhancing Diagnostic Accuracy: Strategies to Mitigate Lipemic Interference in Urea and Creatinine Testing Using Alpha-Cyclodextrin Siti Ramadhani; Riri Safitri; Nur Afni Heryanti Octavia
JURNAL PENGMAS KESTRA (JPK) Vol. 6 No. 1 (2026): Jurnal Pengmas Kestra (JPK)
Publisher : Lembaga Penelitian dan Pengabdian Kepada Masyarakat (LP2M) Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/cn0g6c80

Abstract

The quality of blood samples dictates the validity of clinical laboratory testing. Lipemic serum conditions frequently cause analytical issues due to high lipid particles that interfere with photometer readings in chemistry analyzers. This community service (PkM) program, formatted as a workshop, was implemented to broaden the knowledge and technical proficiency of laboratory personnel. The event involved 30 students from the Medical Laboratory Technology program as participants. The implementation included interactive lectures, visual demonstrations, in-depth discussions on clinical chemistry principles, and hands-on sample management practices in the laboratory. Educational and training materials were specifically designed to ensure that participants could effectively resolve lipid interference and understand the function of alpha-cyclodextrin as a safe clearing agent that does not alter analyte concentrations. The results demonstrated tangible progress among participants in detecting analytical interference caused by lipemia, evidenced by a 33.5-point average increase in cognitive knowledge scores and a 95.0% participant satisfaction rate. Participants are now capable of executing correct pre-analytical steps using alpha-cyclodextrin and obtaining more accurate urea and creatinine measurements. This program underlines the importance of integrating technical problem-solving into human resource competency enhancement activities in the laboratory. Improving participants' understanding of managing problematic specimens contributes directly to enhancing the quality of clinical chemistry examination results and supports the creation of professional, precise, and reliable healthcare services for the community..
Co-Authors Lubis, Basyariah Nur Afni Heryanti Octavia Riri Safitri Sa'adah Siregar Vincentia Ade Rizky Vitra Missi Agatha Agatha