Efficacy of Breast Milk Booster Supplement (BBS) on Breast Milk Volume and Nutrient Content: A Single-Blind Randomized Controlled Trial

Trias Mahmudiono (Department of Nutrition, Faculty of Public Health, Universitas Airlangga, Surabaya, Indonesia)
Qonita Rachmah (Department of Nutrition, Faculty of Public Health, Universitas Airlangga, Surabaya, Indonesia)
Azizah Ajeng Pratiwi (Department of Nutrition, Faculty of Public Health, Universitas Airlangga, Surabaya, Indonesia)
Dayinta Annisa Syaiful (Department of Occupational Health and Safety, Faculty of Public Health, Universitas Airlangga, Surabaya, Indonesia)
Alinda Rahmani (Research Group Center of Health and Nutrition Education, Counselling, and Empowerment (CHeNECE), Surabaya, Indonesia)
Eka Anisah Yusryana (Research Group Center of Health and Nutrition Education, Counselling, and Empowerment (CHeNECE), Surabaya, Indonesia)
Natasya Ayu Andamari (Bunda General Hospital, Jakarta, Indonesia)
Asri Meidyah Agustin (Department of Nutrition, Faculty of Public Health, Universitas Airlangga, Surabaya, Indonesia)

Jurnal Media Gizi Indonesia (MGI)
Vol. 21 No. 3 (2026): MEDIA GIZI INDONESIA

Background: Natural galactagogues are widely used to support lactation, but evidence for their effectiveness remains limited. This study evaluated the effects of a breast milk booster supplement (BBS) containing Moringa oleifera, Channa striata, and Sauropus androgynus on breast milk volume and nutrient composition. Methods: In this single-blind randomized controlled trial, 77 lactating mothers were assigned to receive either BBS or a placebo. Expressed breast milk volume and nutrient composition were assessed at baseline, day 7, and day 28. Nutrient analyses included energy, protein, carbohydrate, calcium, and omega-3 fatty acids, including docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA). Data were analyzed using the Mann-Whitney and Greenhouse-Geisser repeated-measures tests. Results: The intervention group showed a greater increase in expressed breast milk volume than the control group (348.6 vs. 281.8 mL; p=0.016). EPA concentration was significantly higher at day 28 (3.2 mg/100 g; p=0.027). Although DHA and calcium increased to a greater extent in the intervention group, the differences were not statistically significant. Infants in the intervention group also had significantly greater increases in mid-upper arm circumference (MUAC). Conclusion: Twenty-eight days of BBS supplementation increased expressed breast milk volume and EPA content, supporting its potential as a lactation supplement.