Rachmah, Qonita
Departemen Gizi Kesehatan, Fakultas Kesehatan Masyarakat, Universitas Airlangga

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Sensitivity and Specificity of Several Malnutrition Screening Tools for Chronic Kidney Disease Patient: A Narrative Review Qonita Rachmah; Dominikus Raditya Atmaka
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14376

Abstract

Introduction: Malnutrition remains a critical risk factor for morbidity and mortality among CKD patients.However, malnutrition is preventable and treatable. Thus, early malnutrition screening of CKD patients iscrucial. The present paper is a narrative review of the several studies related the use, sensitivity and specificity ofdeveloped malnutrition screening tools for CKD patients.Material and Method: Articles were searched from five electronic databases i.e., PubMed, PMC, Semanticscholar, Science-direct, and Google scholar. Several keywords used for literature searching including“malnutrition screening tools CKD”; “malnutrition CKD”; “malnutrition screening CKD”. Inclusion criteriaof this narrative review was the subject of intervention should be an aged 1 – 64 years old with experimentalrandomized control trial (RCT) or non-RCT study design. The exclusion criteria for this literature studywere research published before 1990, literature studies, meta-analysis, comments, short communication, andeditorial letters. Data then narratively described.Result and Conclusion: Twelve publication were narratively described in final analysis. Development ofmalnutrition screening tools for CKD patient had been done since 1992 and still counting until 2020. At leastthirteen screening tools had been tested for its use, sensitivity and specificity. Among 13 tools we analyzed,Simple Nutrition Screening Tool (SNST) and The Renal Nutrition Screening Tool (R-NST) revealed thehighest sensitivity and specificity value which suitable to be used in adult population, while in children,only Pediatric Digital Scaled MAlnutrition Risk Screening Tool (PeDiSMART) showed a good sensitivityand specificity. Further study should be focusing to look for sensitivity and specificity in other specificpopulation to ensure the right use of malnutrition screening tool.
A SYSTEMATIC REVIEW: ASUPAN ZAT GIZI MAKRO DAN STATUS GIZI PASIEN KANKER YANG MENJALANI KEMOTERAPI A Systematic Review: Macro Nutrient Intake and Nutritional Status of Cancer Patients Undergoing Chemotherapy Sheryll Deby Regyna; Merryana Adriani; Qonita Rachmah
Media Gizi Indonesia Vol. 16 No. 2 (2021): JURNAL MEDIA GIZI INDONESIA (National Nutrition Journal)
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mgi.v16i2.182-193

Abstract

Nutrient intake in cancer patients is diff erent from other disease due to side eff ects of chemotherapy, like nausea, vomit, and appetite loss, which in the long run it have an impact on the nutritional status of patients. The study used systematic reviews to determine side eff ects of chemotherapy on macro nutrient intake and nutritional status of cancer patients in 15 literature. Those literatures were taken from articles published from 2005 to 2019 in PubMed, NCBI, and Google Scholar and all of them were using observational research design. The results of 15 literature showed, there was a decrement in macro nutrient intake including energy, carbohydrates, protein, and fat as a result of chemotherapy side eff ects such as nausea, vomit, and appetite loss. Ten of 15 literature showed the patient nutritional status was underweight, and 5 literature showed overweight and obesity due to the use of corticosteroids as supporting treatment. The future research opportunities that can be carried out a deeper analysis of the relationship of nutritional intake and changes in nutritional status of patients with longer duration for the research, measurement methods by using gold standards which are weighing food record, as well as diff erent types of cancer.
PENINGKATAN PENGETAHUAN DAN SELF-EFFICACY UPAYA PENCEGAHAN COVID-19 MELALUI EDUKASI GIZI KONVENSIONAL Increased Knowledge and Self-Efficacy of COVID-19 Prevention through Conventional Nutrition Education Qonita Rachmah; Triska Susila Nindya; Arif Sabta Aji; Sitti Patimah; Nabilla Rachmah; Nabiil Ikbaar Maulana; Asri Meidyah Agustin; Junaida Astina
Media Gizi Indonesia Vol. 16 No. 3 (2021): JURNAL MEDIA GIZI INDONESIA (NATIONAL NUTITRION JOURNAL)
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mgi.v16i3.273-279

Abstract

The COVID-19 pandemic has impact on various sectors, especially in the health sector. Efforts to prevent COVID- 19 can be done through the application of health protocols and balanced nutrition intake. There were a lot of misinformations related to COVID-19 prevention that might be a risk of increasing positive rate cases. The aim of this study was to determine the effectiveness of conventional nutrition education on knowledge and self-efficacy of COVID-19 prevention efforts. Study subjects of this study were 23 adults aged 19-65 years and taken by total sampling method. Nutritional knowledge data were collected using a questionnaire containing ten questions, while self-efficacy was assessed by creating a structured questionnaire on a scale of 0-100. Conventional education was given in the form of lectures related to the role of balanced nutrition, hoaxes related to food to prevent or treat COVID-19, and other COVID-19 prevention efforts for 90 minutes. Before and after education data were analyzed using paired t-test with SPSS version 23. This study results showed that nutrition education significantly improves nutritional knowledge (mean score before and after = 69.6 + 10.2 and 85.7 + 10.4; p < 0.001), self-efficacy to apply a balanced nutrition pattern (mean scores before and after = 68.2 + 13.0 and 75.5 + 17.5; p = 0.014), and the self-efficacy of implementing the health protocol (mean score before and after = 82.3 + 7.8 and 87.0 + 6.8; p = 0.002). This research can be used as a benchmark for the importance of expanding the coverage of conventional nutrition education to the wider community.
Thirty Days Snail Biscuit Supplementation Improved Height-for-age Z-score (HAZ) of Malnourished Children in Slum Surabaya Trias Mahmudiono; Zeni Firginingtyas; Qonita Rachmah
Amerta Nutrition Vol. 1 No. 1 (2017): AMERTA NUTRITION
Publisher : Universitas Airlangga, Kampus C, Mulyorejo, Surabaya-60115, East Java, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (703.638 KB) | DOI: 10.20473/amnt.v1i1.2017.31-37

Abstract

Background: Indonesia is now still suffering from malnutrition. It was reported that at least 1.39% out of 136,155 children under-five in Surabaya were severely. Severe malnutrition caused by direct factors including infectious diseases and food intake. Therefore, an alternative to overcome that problem is crucial, such as using snail flour for a weaning food. Snail is known as one of the good protein source with complete essential amino acid.Objective: This research aims to determine the effect of snail biscuit (Achatina fulica) toward z-score improvement in severely malnourished children under five according weight for age and height for age index in Ujung sub-district, Surabaya.Methods: This was an experimental research which divided into two groups; case group that given snail biscuit for a month and control group that given coconut biscuit in a same time period. Paired t-test was done to analyze the different between before and after treatment.Results: The result showed that there was no effect of snail biscuit to weight-for-age z-score (WAZ) improvement in children under five (p-value>0.05). However, a month snail biscuit intervention improved height-for-age z-score (HAZ) in children under five (p-value=0.02); while the control group did not show significant result (p-value=0.84). The strength of intervention shown by Exp(B) value=1.02 means that children under five who consume snail biscuit for a month had 1.02 higher height-for-age z-score improvement compared to those who consumed coconut biscuit.Conclusion: It can be concluded that snail biscuit give better improvement of nutritional status based on height-for-age z-score compared to coconut biscuit in malnourished children under five. It is suggested for the intervention study to expand intervention period to 90 days similar to government supplementary feeding intervention. ABSTRAK Latar belakang: Malnutrisi masih menjadi masalah gizi utama yang dialami di Indonesia. Dinas Kesehatan Kota Surabaya pada tahun 2009 melaporkan sebesar 1,888 (1.39%) dari 136,155 balita mengalami gizi buruk. Penyebab gizi buruk terdiri dari faktor langsung dan tidak langsung, dimana faktor langsung terdiri dari penyakit infeksi dan asupan makanan. Salah satu alternatif yang dapat digunakan adalah penggunaan tepung bekicot sebagai makanan pendamping. Bekicot diketahui sebagai salah satu sumber protein dengan kandungan asam amino esensial yang lengkap.Tujuan: Penelitian ini bertujuan untuk mengetahui efek pemberian biskuit bekicot  (Achatina fulica) pada perbaikan z-score berat badan menurut usia dan tinggi badan menurut usia balita gizi buruk di Kelurahan Ujung, Surabaya.Metode: Penelitian ini menggunakan desain studi eksperimental dengan pembagian dua kelompok; kelompok intervensi yang diberikan biskuit bekicot selama 30 hari dan kelompok kontrol yang diberikan biskuit kelapa dalam jangka waktu yang sama. Uji statistik yang digunakan yaitu paired t-test.Hasil: Hasil analisis menunjukkan tidak ada efek pemberian biskuit bekicot selama satu bulan pada indeks status gizi berat badan menurut umur (BB/U) (P-value>0,05). Namun, intervensi pemberian biskuit bekicot secara statistik mempengaruhi perbaikan status gizi tinggi badan menurut usia (TB/U) pada balita gizi buruk, sedangkan biskuit kelapa tidak mempengaruhi TB/U balita gizi buruk (P-value=0.84). Kekuatan pengaruh intervensi berdasarkan perhitungan Exp(B)=1.02, artinya bahwa balita gizi buruk yang mengonsumsi biskuit bekicot memiliki 1.02 kali perbaikan yang lebih baik pada status gizi TB/U dibandingkan balita yang mengonsumsi biskuit kelapa.Kesimpulan: Dapat disimpulkan bahwa biskuit bekicot dapat menjadi alternatif perbaikan status gizi balita gizi buruk. Penelitian selanjutnya disarankan dapat memperpanjang durasi intervensi hingga 90 hari seperti anjuran pemerintah dalam pemberian makan tambahan.
Pendidikan Gizi Gemar Makan Ikan Sebagai Upaya Peningkatan Pengetahuan Ibu tentang Pencegahan Stunting Di Desa Gempolmanis Kecamatan Sambeng Kabupaten Lamongan Provinsi Jawa Timur Qonita Rachmah; Diah Indriani; Susi Hidayah; Yurike Adhela; Trias Mahmudiono
Amerta Nutrition Vol. 4 No. 2 (2020): AMERTA NUTRITION
Publisher : Universitas Airlangga, Kampus C, Mulyorejo, Surabaya-60115, East Java, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (303.87 KB) | DOI: 10.20473/amnt.v4i2.2020.165-170

Abstract

Background: Stunting is one of nutritional problem that causes long-term health problems. Based on the result of Riskesdas, there has been an increase in stunting prevalence from 35,6% in 2010 to 37,2% in 2013 which means that 1 in 3 indonesian children are stunting. Lamongan was one of hundred’s stunting priority regency in Indonesia. This study aims to analyze the effect of nutrition education to incerase mother’s knowledge related stunting.Objective: The method used in this research is Quasi Experiment by designing one group pre-test and post-test design. The sampling technique used was total sampling method in which all mothers with children aged 0 - 59 months in Gempolmanis village, Sambeng District, Lamongan Regency. The Gempolmanis village was purposively chosen.Methods: The dependent T test was used to determine the effect of nutrition education on maternal knowledge. The response rate of this study was 86.4%.Results: The results showed at the beginning of the session, the majority of mothers still had sufficient knowledge (57.9%) and less (36.8%). Only 5.3% have good nutrition knowledge, but after nutrition education, 68.4% of mothers have a good level of knowledge related to stunting. The mean score before nutrition education was 60.5 + 18.9 and increased to 88.4 + 13.8 after nutrition education (p <0.05).Conclusion: It can be concluded that nutrition education can significantly increase maternal knowledge related to the prevention of stunting in children at the golden age. Regular nutrition education by the nutrition officer or posyandu cadre needs to be done as an effort to improve stunting. ABSTRAK Latar belakang : Stunting merupakan salah satu permasalahan gizi dengan dampak kesehatan yang serius. Hasil riskesdas terbaru di tahun 2018 menunjukkan prevalensi stunting sebesar 30,8%, yang artinya 1 dari 3 anak indonesia masih mengalami stunting.  Kabupaten Lamongan merupakan satu dari 100 kabupaten prioritas stunting di Indonesia.Tujuan : Tujuan dari penelitian ini adalah untuk menganalisis pengaruh pemberian pendidikan gizi terhadap pengetahuan ibu tentang Pencegahan Stunting. Metode : Metode yang digunakan dalam penelitian ini adalah Quasi Eksperimen dengan rancangan one group pre-test and post-test design. Teknik pengambilan sampel menggunakan metode total sampling yaitu mengambil semua ibu dengan balita usia 0 – 59 bulan di desa Gempolmanis, Kecamatan Sambeng, Kabupaten Lamongan sebanyak 22 ibu balita. Pemilihan desa Gempolmanis dipilih secara purposive. Uji T dependen digunakan untuk mengukur perbedaan tingkat pengetahuan ibu setelah diberikan pendidikan gizi. Response rate penelitian ini sebesar 86,4%.Hasil : Hasil penelitian menunjukkan pada awal sesi sebelum diberikan pendidikan gizi tentang stunting, mayoritas ibu masih memiliki pengetahuan yang cukup (57,9%) dan kurang (36,8%). Hanya 5,3% yang memiliki pengetahuan gizi baik, namun setelah edukasi gizi, 68,4% ibu memiliki tingkat pengetahuan baik. Rerata skor sebelum edukasi sebesar 60,5 + 18,9 dan meningkat menjadi 88,4 + 13,8 setelah edukasi gizi (P<0.05).Kesimpulan : Dapat disimpulkan bahwa pendidikan gizi secara signifikan dapat meningkatkan pengetahuan ibu terkait pencegahan stunting pada anak di usia golden period. Pemberian edukasi gizi secara berkala baik oleh petugas gizi puskesmas maupun kader posyandu perlu dilakukan sebagai upaya pencegahan stunting.
Gambaran Sisa Makanan Pasien Rawat Inap RSUD Kabupaten Sidoarjo Chusnul Fadilla; Qonita Rachmah; Juwariyah Juwariyah
Amerta Nutrition Vol. 4 No. 3 (2020): AMERTA NUTRITION
Publisher : Universitas Airlangga, Kampus C, Mulyorejo, Surabaya-60115, East Java, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/amnt.v4i3.2020.198-204

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ABSTRACTBackground: The quality of nutrition services can be seen through the patient's leftovers as the result of hospital food system management. High food waste could impact on increasing the risk of malnutrition in hospitalized patients.Objective: This study aimed to determine the food waste description among patients in Sidoarjo General Hospital. Method: This was a descriptive study used a cross-sectional design with a total sample of 150 patients selected by proportional sampling in each in patient room during September 2019. Data was taken using the comstock form and then translated into percent of food waste and lost of food costs.Results: The highest percentage of leftovers from hospitalized patients was found in vegetable side dishes (30.72%) and the lowest was in animal side dishes (21.81%). The higher class of inpatient room, the lower the percentage of food waste. Foods that were intact by patients were highest during dinner (38.0%). The highest loss due to costs lost from whole food came from inpatient class I which amounted to IDR 1,680,000.Conclusion: The food waste of inpatients at Sidoarjo General Hospital was still quite high. Evaluation of factors causing high food waste in inpatients can be done to reduce percent of food waste and food cost efficiency.ABSTRAK Latar Belakang: Kualitas mutu pelayanan gizi dapat dilihat melalui sisa makanan pasien hasil manajemen penyelenggaraan makanan rumah sakit. Tingginya sisa makanan dapat berdampak pada peningkatan risiko malnutrisi pada pasien rawat inap.Tujuan: Penelitian ini bertujuan untuk mengetahui gambaran sisa makanan pasien rawat inap di RSUD Kabupaten Sidoarjo.Metode: Penelitian deskriptif ini menggunakan desain potong lintang dengan jumlah sampel sebanyak 150 pasien dipilih secara proportional sampling di masing-masing ruangan rawat inap pada bulan September 2019. Data diambil menggunakan formulir comstock lalu diterjemahkan dalam bentuk persen sisa makanan dan foodcost yang hilang. Tingginya persentase makanan ditentukan dengan standar Depkes 2013 yaitu apabila melebihi 20%.Hasil: Persentase sisa makanan pasien rawat inap tertinggi ditemukan pada lauk nabati (30,72%) dan terendah pada lauk hewani (21,81%). Semakin tinggi kelas rawat inap, maka semakin rendah persentase sisa makanan. Makanan yang utuh atau tidak tersentuh oleh pasien paling tinggi terjadi saat makan sore (38,0%). Kerugian tertinggi akibat biaya yang hilang dari makanan utuh berasal dari rawat inap kelas I yaitu sebesar Rp. 1.680.000,00.Kesimpulan: Sisa makanan pasien rawat inap di RSUD Kabupaten Sidoarjo masih tergolong cukup tinggi. Evaluasi faktor penyebab tingginya sisa makanan pada pasien rawat inap dapat dilakukan untuk menurunkan persen sisa makanan dan efisiensi foodcost.
The Effectiveness of Mobile Device-Based Digital Interventions on the Risk Factors of Diabetes Mellitus Control in the Industrial Revolution 4.0 Ratna Kuatiningsari; Fatqiatul Wulandari; Ade Lia Ramadani; Qonita Rachmah
Amerta Nutrition Vol. 5 No. 4 (2021): AMERTA NUTRITION
Publisher : Universitas Airlangga, Kampus C, Mulyorejo, Surabaya-60115, East Java, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/amnt.v5i4.2021.320-325

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ABSTRACTBackground: Diabetes mellitus is a chronic disease which if not done properly, can cause microvascular and macrovascular disorders. Indicators of the accuracy of diabetes management in this scientific article include education, self-management (improving diet, increasing physical activity, and self-efficacy), and monitoring of HbA1c levels. Mobile devices have the potential as a tool for diabetes mellitus management in the era of the industrial revolution 4.0.Purpose: to provide the latest information regarding the effectiveness of using mobile devices in controlling risk factors for diabetes mellitus.Method: This study is a literature review study. The electronic databases used are Google Scholar, Science Direct, and Directory of Access Journals (DOAJ). Inclusion criteria: original research, a journal of at least 80% indexed by Sinta (Indonesian journal) and indexed by Scopus (international journal), published year 2010-2020, intervention using a mobile device, has an output of HbA1c levels, self management (diet, physical activity, and self efficacy), and the level of knowledge. Exclusion criteria: reference with secondary data.Result: This study used 16 scientific articles. A number of 12 studies (75%) reported the use of mobile device applications in controlling risk factors for diabetes mellitus had significant measurement results in controlling HbA1c levels in 10 studies (83%) and 2 studies were not significant (17%). Outcomes in the form of self-management were reported by 9 studies with details of the significant results of dietary improvement in 5 studies (83%), increased physical activity in 5 studies (63%), and self-efficacy in 4 studies (67%). The increase in knowledge was reported by 4 studies with significant results (100%).Conclusion: Mobile device-based digital intervention is quite effective in controlling diabetes mellitus risk factors to control HbA1c levels, increasing self-management (improving diet, increasing physical activity, and self-efficacy) and knowledge. 
The Relationship Habits of Through Breakfast and Physical Activity with Abdominal Obesity in Nutrition Students Martha Ria Wijayanti; Sri Adiningsih; Qonita Rachmah
Amerta Nutrition Vol. 5 No. 2 (2021): AMERTA NUTRITION
Publisher : Universitas Airlangga, Kampus C, Mulyorejo, Surabaya-60115, East Java, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/amnt.v5i2.2021.115-120

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Background : Abdominal obesity is obesity characterized by the accumulation of excess fat in the abdominal area. The risk of metabolic and cardiovascular disease may increase due to abdominal obesity. One of the factors associated with abdominal obesity is imbalance between energy intake and physical activity. Several studies have stated that skipping breakfast is associated with an increased risk of obesity with the tendency to consume high calorie foods to provide energy for activities.Objectives : The purpose of this study is to analyze the relationship between skipping breakfast, level of physical activity and obesity in nutrition students at Public Health Faculty, Airlangga University.Methods : This research is observational analytic with cross sectional design. The population in this study were nutrition students at Public Health Faculty, Airlangga University. The number of samples was 60 people which selected by proportional random sampling method. Data were collected include the measurements of waist circumference, interviews using respondent's identity questionnaire and physical activity recall 3 x 24 hours. Data were analyze with Spearman correlation test.Results : Based on the results, it was found that 33.3% of the respondents were obese. The results of statistical tests shows a negative correlation between skipping breakfast and abdominal obesity (p = 0.000). The results of this study also showed that there is no significant correlation between the level of physical activity and obesity (p = 0.618).Conclusions : Skipping breakfast was significantly associated with abdominal obesity in the young adult students group. Therefore, it is better if the habits of skipping breakfast can be replaced with breakfast habits to prevent abdominal obesity. 
“Apakah Tubuhku Terlihat Baik?” Analisis Fenomena Swafoto pada Social Networking Sites dengan Eating Disorders : Systematic Review Qonita Rachmah; Dominikus Raditya Atmaka, S.Gz, MPH; Stefania Widya Setyaningtyas; Mahmud Aditya Rifqi; Rian Diana; Nila Reswari Haryana; Aliffah Nurria Nastiti; Asri Meidyah Agustin
Amerta Nutrition Vol. 6 No. 3 (2022): AMERTA NUTRITION
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/amnt.v6i3.2022.306-314

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Latar Belakang: Penggunaan sosial media dapat membawa dampak negatif kaitannya dengan ketidakpuasan akan bentuk tubuh dan arahan menuju ke kekurusan (drive to thinness) terutama pada perempuan muda, perhatian belebih pada citra tubuh (body image concern), dan berbagai isu terkait kebiasaan makan yang salah. Tujuan: Penelitian ini bertujuan untuk mengetahui hubungan kebiasaan mengunggah swafoto pada Social Networking Sites (SNS) dengan kejadian eating disorders pada sejumlah negara serta faktor-faktor yang mungkin mempengaruhi. Ulasan:  Kondisi eating disorders sering tidak disadari oleh individu, terutama pada kelompok remaja dan dewasa muda. Data terkait prevalensi eating disorders di Indonesia juga sangat terbatas, padahal, penggunaan media sosial di kalangan remaja dan dewasa muda Indonesia semakin meningkat seiring dengan mudahnya akses internet dan perkembangan platform media sosial. Dari review sistematik yang dilakukan, hanya satu studi yang mendapatkan keterkaitan antara unggahan swafoto (selfie) dengan eating disorders, yaitu bulimia. Namun, hampir semua memiliki kesimpulan bahwa penggunaan sosial media berkaitan dengan rendahnya kepercayaan diri,   ketidakpuasan terhadap bentuk tubuh, citra diri negatif, serta berkaitan dengan karakteristik restriksi pola makan berlebihan. Kesimpulan: Telaah sistematik ini dapat menjadi acuan untuk pengembangan penelitian kedepan dengan memperhatikan fenomena sosial, penggunaan sosial media dan kaitannya dengan eating disorders maupun status gizi remaja dan dewasa awal.
Roles of Vitamins in Immunity and COVID-19: A Literature Review Nila Reswari Haryana; Qonita Rachmah; Mahmud Aditya Rifqi; Rian Diana; Dominikus Raditya Atmaka; Stefania Widya Setyaningtyas; Aliffah Nurria Nastiti; Asri Meidyah Agustin
Media Gizi Indonesia Vol. 17 No. 3 (2022): JURNAL MEDIA GIZI INDONESIA (NATIONAL NUTRITION JOURNAL)
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mgi.v17i3.224-233

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SARS-CoV-2 is a severe acute respiratory virus that causes Coronavirus Disease-19 (COVID-19). Even before the COVID-19 pandemic, diet was undeniably important in immunity. In order to be more resilient during and after the pandemic, understanding the role of vitamins is crucial. This review aims to explore the role of vitamins in supporting the immune system and its correlation to COVID-19. The article search was done using five electronic databases (i.e., Google Scholar, Semantic Scholar, ScienceDirect, PubMed, and PMC). Some of the keywords utilized in the literature search were “vitamin A and immunity” OR “vitamin B and immunity” OR “vitamin C and immunity” OR “vitamin D and immunity” OR “vitamin E and immunity”. A total of 51 articles was assessed in this literature review. Research finds vitamin A plays a role in both innate immune system cell function and humoral immunity by regulating, differentiating, and maturing immune system cells. Vitamin B complex primarily reduces inflammation by lowering serum C-reactive protein levels (CRP), while vitamin C strengthens epithelial barriers, phagocytes, T and B lymphocytes, and inflammatory mediators, to improve the immune system. Vitamin D acts as a mediator in the vitamin D receptor (VDR), an inner immune system component that regulates the humoral and adaptive immune systems through unique genetic transcriptions. Finally, vitamin E acts as an antioxidant, lowering the production of reactive oxygen and nitrogen species (ROS and RNS). In conclusion, all vitamins are essential in improving individual’s immune system that prevent from infectious diseases including COVID-19.
Co-Authors Adamina Dinda Roseprilla Ade Lia Ramadani Adila, Yulia Agustin Asri Meidyah Agustin, Asri Meidyah Alifah Nurria Nastiti Aliffah Nurria Nastiti Amila Nurdin Andamarai, Natasya Ayu Anisa Lailatul Fitria Anisa Lailatul Fitria Anisa Lailatul Fitria Aprilia Durotun Nasikhah Arif Sabta Aji Arum Damar Aditya Bayu Sukma Asri Meidyah Agustin Asri Meidyah Agustin Asri Meidyah Agustin Asri Meidyah Agustin Asri Meidyah Agustin Asri Meidyah Agustin Avilla Arsa Azizah Ajeng Pratiwi Azizah Ajeng Pratiwi Azizah Ajeng Pratiwi Chusnul Fadilla Diah Indriani Dominikus Raditya Atmaka Endah Sarworini Erwanda Anugrah Permatasari Farapti Farapti Fatqiatul Wulandari Fatqiatul Wulandari Fermeza, Ratu Dien Prima Hario Megatsari Haryana, Nila Reswari Hedianti, Diah Riski Ismayani Junaida Astina Juwariyah Juwariyah Khoridah Annabila Lailatul Muniroh Lilis Sulistyorini Mahmud Aditya Rifqi Maris Mumtaza Martha Ria Wijayanti Merryana Adriani Mohammad Fahmi Rasyidi Muhammad Ziddan Zaelani Nabiil Ikbaar Maulana Nabila Mutia Rahma Nabilla Rachmah Nabilla Rachmah Nandia Firsty Dhorta Nastiti, Aliffah Nurria Nastiti, Aliffah Nurria Nila Reswari Haryana Nor, Norfezah Md Nurul Qomariyah Pratiwi Azizah Ajeng Pratiwi, Azizah Ajeng Purnomo, Muhammad andy Dwi Rahmani, Alinda Ratna Kuatiningsari Rian Diana Rian Diana Rian Diana Riris Diana Rachmayanti Rochmah, Thini Nurul Sabrina, Hasna Nur Salsabila Meivitama Arsanti Sheryll Deby Regyna Shrimarti Rukmini Devy Sianturi, Olivia Siti Helmyati Siti Rahayu Nadhiroh Sitti Patimah Sri Adiningsih Sri Andari, Sri Stefania Widya Setyaningtyas Susi Hidayah Tia Eka Novianti Tiara Tivany Simangunsong Trias Mahmudiono Triska Susila Nindya Ulya, Rufaida Adya Nur Avianti Varera, Yolanda Eggy Wigati Maria Wuri Diah Handayani Yurike Adhela Yusryana, Eka Anisah Zeni Firginingtyas