This study aims to determine the effectiveness of the use of interactive multimedia based on Google Sites on the learning outcomes of class XI students of SMA Negeri 2 Palopo on the Excretory System material. This study is part of the development research with the ADDIE model. The sample in this study was class XI.3 Avicenna with a total of 33 students. The research instrument used was a learning outcome test. The data analysis technique in this study used an effectiveness test. The results showed that the effectiveness test was in the very valid criteria with a value of 84%. This criterion indicates that interactive multimedia based on Google Sites is effective in improving student learning outcomes so that it can be an alternative learning media for biology, especially on the Excretory System material.
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