JOURNAL OF Pharmacy and Tropical Issues
Vol. 6 No. 3 (2026): July Edition 2026

Hubungan antara kepatuhan penggunaan obat dengan keberhasilan terapi pada pasien hipertiroid usia produktif

Neng Widiyah Hikmah Syaripah (Fakultas Kedokteran, Universitas Malahayati)
Mala Kurniati (Fakultas Kedokteran, Universitas Malahayati)
Veronica Ela Rimawati (Fakultas Kedokteran, Universitas Malahayati)
Toni Prasetia (Fakultas Kedokteran, Universitas Malahayati)



Article Info

Publish Date
25 Jul 2026

Abstract

Background: Hyperthyroidism is an endocrine disorder caused by the excessive production of thyroid hormones, which can lead to complications if not properly managed. Treatment success in patients with hyperthyroidism is influenced by medication adherence. Purpose: To determine the relationship between medication adherence and treatment success in patients of productive age with hyperthyroidism. Method: This was an analytic observational study with a cross-sectional design. The study sample consisted of 54 respondents selected using purposive sampling. Adherence levels were measured using the Morisky Medication Adherence Scale-8 (MMAS-8) questionnaire, while treatment success was assessed based on thyroid hormone test results and clinical symptom improvement recorded in patient medical records. Data analysis was conducted using univariate and bivariate methods, employing the chi-square test. Results: The results show that the respondents' mean TSH levels decreased from 6.87 mIU/L to 3.21 mIU/L following therapy. The majority of respondents demonstrated adherence levels ranging from low to high and achieved successful therapeutic outcomes. There is an association between medication adherence and therapeutic success in patients with hyperthyroidism. Conclusion: Medication adherence is associated with therapeutic success in hyperthyroid patients of working age. The higher the level of patient adherence to treatment, the greater the therapeutic success achieved. Suggestion: Ongoing education, monitoring, and support from healthcare professionals are required to improve patient adherence.   Keywords: Health Belief Model; Hyperthyroidism; Medication Adherence; MMAS-8; Treatment Success.

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Journal Info

Abbrev

pti

Publisher

Subject

Medicine & Pharmacology

Description

Jurnal penelitian dibidang kesehatan meliputi ilmu keparmasian. Penelitain sesuai tren pengobatan sesuai sumber alam di negara tropis. Pengembangan obat dan pendistribusian kepada pelanggan, dan sesuai aturan Badan Pengawas Obat dan Makanan (BPOM) - Republik ...