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All Journal Jurnal Ilmu Kedokteran dan Kesehatan JOURNAL OF Pharmacy and Tropical Issues Journal of Medical Surgical Concerns
Mala Kurniati
Fakultas Kedokteran, Universitas Malahayati
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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Pengaruh Pemberian Susu Beras Terhadap Pertumbuhan Mencit Model Stunting Nafa Amalia; Dalfian Dalfian; Arti Febriyani; Mala Kurniati; Zulhafis Mandala
Jurnal Ilmu Kedokteran dan Kesehatan Vol 13, No 2 (2026): Volume 13 Nomor 2
Publisher : Prodi Kedokteran Fakultas Kedokteran Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jikk.v13i2.22203

Abstract

Stunting merupakan masalah gizi kronis yang berdampak pada pertumbuhan dan perkembangan anak. Pemberian susu beras berpotensi menjadi solusi alternatif dan ekonomis untuk menangani stunting. Studi ini dilaksankan untuk mengetahui pengaruh pemberian susu beras terhadap pertumbuhan mencit (Mus musculus) model stunting. Studi ini berjenis eksperimental in vivo dengan desain Randomized Controlled Trial (RCT), pre and post test with control group design, menggunakan 25 ekor mencit jantan strain C57BL/6. Induksi stunting dilakukan melalui pemberian diet rendah protein selama 21 hari dan indometasin selama 7 hari. Subjek dikelompokkan dalam lima kelompok: kontrol normal (KN), kontrol negatif (K-), perlakuan susu beras 1 x sehari (K+), perlakuan susu beras 2 x sehari (KP1), dan perlakuan susu beras 3 x sehari (KP2). Parameter yang diukur ialah berat badan dan panjang ekor sebelum dan sesudah perlakuan. Hasil uji menunjukkan tidak terdapat pengaruh signifikan secara statistik pada peningkatan berat badan untuk kelompok K+ (p = 0,376) dan KP2 (p = 0,376). Demikian pula pada hasil uji panjang ekor, tidak ditemukan pengaruh signifikan pada kelompok K+ (p = 0,796) dan KP2 (p = 0,796). Secara deskriptif, pemberian susu beras menunjukkan tren pertumbuhan linier pada berat badan dan panjang ekor mencit model stunting, meskipun belum menunjukkan bukti statistik yang kuat dalam studi ini.
Comparison of dermatoglyphic patterns between children with and without Down syndrome Nitra Syafa Irzika; Mala Kurniati; Zulhafis Mandala; Astri Pinilih
JOURNAL OF Medical Surgical Concerns Vol. 6 No. 3 (2026): July Edition 2026
Publisher : Published by: Indonesian Public Health-Observer Information Forum (IPHORR) Kerjasama dengan Himpunan Perawat Medikal Bedah Indonesia (HIPMEBI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56922/msc.v6i3.3781

Abstract

Background: Dermatoglyphic patterns develop during embryogenesis and are influenced by genetic and intrauterine factors. Trisomy 21 may alter epidermal ridge formation, making fingerprint patterns a potential non-invasive supportive marker of developmental variation. Purpose: To compare participant-level categorical fingerprint patterns between children with and without Down syndrome. Method: This comparative cross-sectional study included 59 participants: 29 children with Down syndrome and 30 children without Down syndrome. Fingerprint impressions were obtained using an ink pad and fingerprint paper, and each child was assigned one participant-level category (loop, whorl, or arch). Fisher's exact test compared the loop and whorl distributions because no arch patterns were observed; p < 0.05 was considered statistically significant. Results: Loop patterns were reported in 23 children with Down syndrome (79.3%) and 27 children without Down syndrome (90.0%). Whorl patterns were reported in 6 children with Down syndrome (20.7%) and 3 children without Down syndrome (10.0%); no arch patterns were identified. The distribution was not significantly different between groups (p = 0.299). Conclusion: Participant-level loop, whorl, and arch pattern distributions were not significantly different between children with and without Down syndrome in this sample. These broad categories should not be interpreted as a stand-alone diagnostic marker.
Efektivitas biogenik silver nanopartikel (AgNPs) dalam sediaan gel terhadap pertumbuhan Propionibacterium acnes dan bakteri patogen luka Shabina Adinia Yonny; Ratna Purwaningrum; Mala Kurniati; Dwi Marlina Syukri
JOURNAL OF Pharmacy and Tropical Issues Vol. 6 No. 3 (2026): July Edition 2026
Publisher : Indonesian Public Health-Observer Information Forum (IPHORR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56922/pti.v6i3.3749

Abstract

Background: Acne and wound infections are health issues frequently caused by pathogenic bacteria such as Propionibacterium acnes, Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli, Klebsiella pneumoniae, and Acinetobacter baumannii. Rising antibiotic resistance is driving the development of alternative antibacterial agents. Purpose: To determine the effectiveness of biogenic silver nanoparticles (AgNPs) in gel preparations synthesized using Eucalyptus pellita leaf extract against the growth of Propionibacterium acnes and wound pathogenic bacteria. Method: This was an experimental laboratory study using a post-test-only control group design. Antibacterial activity was tested using the well-diffusion method. The results showed that the AgNP gel inhibited the growth of all tested bacteria. The largest inhibition zone diameter was observed against Propionibacterium acnes, measuring 26.67 ± 2.309 mm. Results: The two-way ANOVA test showed a significant difference between bacterial types and treatment groups (p<0.001). Conclusion: Biogenic silver nanoparticles (AgNPs) in gel formulations exhibit antibacterial activity and have the potential to be developed as alternative antibacterial agents.   Keywords: AgNPs; Antibacterial; Eucalyptus Pellita; Propionibacterium Acnes; Wound Pathogenic Bacteria.
Hubungan antara kepatuhan penggunaan obat dengan keberhasilan terapi pada pasien hipertiroid usia produktif Neng Widiyah Hikmah Syaripah; Mala Kurniati; Veronica Ela Rimawati; Toni Prasetia
JOURNAL OF Pharmacy and Tropical Issues Vol. 6 No. 3 (2026): July Edition 2026
Publisher : Indonesian Public Health-Observer Information Forum (IPHORR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56922/pti.v6i3.3786

Abstract

Background: Hyperthyroidism is an endocrine disorder caused by the excessive production of thyroid hormones, which can lead to complications if not properly managed. Treatment success in patients with hyperthyroidism is influenced by medication adherence. Purpose: To determine the relationship between medication adherence and treatment success in patients of productive age with hyperthyroidism. Method: This was an analytic observational study with a cross-sectional design. The study sample consisted of 54 respondents selected using purposive sampling. Adherence levels were measured using the Morisky Medication Adherence Scale-8 (MMAS-8) questionnaire, while treatment success was assessed based on thyroid hormone test results and clinical symptom improvement recorded in patient medical records. Data analysis was conducted using univariate and bivariate methods, employing the chi-square test. Results: The results show that the respondents' mean TSH levels decreased from 6.87 mIU/L to 3.21 mIU/L following therapy. The majority of respondents demonstrated adherence levels ranging from low to high and achieved successful therapeutic outcomes. There is an association between medication adherence and therapeutic success in patients with hyperthyroidism. Conclusion: Medication adherence is associated with therapeutic success in hyperthyroid patients of working age. The higher the level of patient adherence to treatment, the greater the therapeutic success achieved. Suggestion: Ongoing education, monitoring, and support from healthcare professionals are required to improve patient adherence.   Keywords: Health Belief Model; Hyperthyroidism; Medication Adherence; MMAS-8; Treatment Success.
Co-Authors Arti Febriyani Astri Pinilih Dalfian Dalfian Dwi Marlina Syukri Nafa Amalia Neng Widiyah Hikmah Syaripah Nitra Syafa Irzika Ratna Purwaningrum Shabina Adinia Yonny Toni Prasetia Veronica Ela Rimawati Zulhafis Mandala