<![CDATA[Hypertension is one of the global public health challenges that reduces patients' quality of life (QoL). Psychosocial determinants such as anxiety, family support, coping mechanisms, perceptions of illness, and motivation to recover play an important role but are often overlooked. Analysing psychosocial determinants of quality of life among hypertensive patients in semi-urban areas. A cross-sectional study was conducted on 938 hypertensive patients in Kotamobagu City, Indonesia (May–July 2025) using stratified random sampling, data were collected using standard instruments: WHOQOL-BREF (QoL), State-Trait Anxiety Inventory (anxiety), Family APGAR (family support), Coping Inventory (coping mechanisms), Brief Illness Perception Questionnaire (illness perception), and Treatment Self-Regulation Questionnaire (motivation). Chi-square analysis and logistic regression were performed using SPSS 27. Adaptive coping mechanisms were the dominant predictor with the largest contribution in the model (OR = 3.10; Wald = 203.68). Motivation to recover was a strong predictor, but not dominant (OR = 3.67; Wald = 49.00). Positive perception of illness can be used as an additional strong predictor (OR = 3.67; Wald = 30.25). Adaptive coping strategies, including task-oriented, cognitive, emotional, social, and spiritual strategies, as well as social support and resilience, play a dominant role in improving quality of life and managing hypertension.]]>
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