<![CDATA[This study developed a science process skills-based electronic student worksheet (E-LKPD) for Grade XI biology and evaluated its validity, practicality, and effectiveness in improving students’ critical thinking skills and scientific literacy. A Research and Development (R&D) approach using the 4-D model (Define, Design, Develop, and Disseminate) was employed. Product validity was assessed by subject-matter, instructional design, and layout design experts, while practicality was evaluated through individual (n = 3), small-group (n = 9), and limited-group (n = 21) trials. Effectiveness was tested using experimental and control groups, each consisting of 26 students. Validation scores were 87.5%, 92.8%, and 95.0% for subject matter, instructional design, and layout, respectively, all categorized as very good. Practicality scores were 90.0%, 91.7%, and 93.0% across the three trial stages. In the experimental group, the mean critical thinking and scientific literacy scores were 86.31 and 87.58, respectively. The N-Gain was 0.72 in the experimental group and 0.40 in the control group, indicating high and moderate improvement, respectively. The independent-samples t-test showed a significant difference between groups (t = 5.80, p < 0.05). These findings indicate that the developed E-LKPD is valid, practical, and effective in improving students’ critical thinking skills and scientific literacy.]]>
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